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Screening of Biological Activities of Extracts from Rhododendron mucronulatum Turcz. Flowers (진달래꽃(Rhododendron mucronulatum Turcz. Flower) 추출물의 생리활성 탐색)

  • Cho, Young-Je;Ju, In-Sik;Chun, Sung-Sook;An, Bong-Jeun;Kim, Jeung-Hoan;Kim, Myung-Uk;Kwon, Oh-Jun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.3
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    • pp.276-281
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    • 2008
  • Extracts from Rododendron mucronulatum Turcz. flowers were tested for antioxidant and their inhibitory activities of ${\alpha}$-amylase, ${\alpha}$-glucosidase and angiotensin converting enzyme (ACE). Total contents of phenolics were found as $30.6{\pm}0.14mg/g$ (60% EtOH extract) and $23.2{\pm}0.21mg/g$ (water extract). Electron donation ability (EDA), ABTS [2,2azinobis(3-ethylbenzothiazoline-6-sulfonic acid)] radical decolorization, Antioxidant protection factor (PF) and thiobarbituric acid reactive substance (TBARs) were measured for the antioxidative activity of the extracts from Rododendron mucronulatum Turcz. flowers. The water extract were determined as 97.5% at ethanol extract showed 83.2% and 60% EtOH extract were 89.7% in EDA. The water extract showed higher antioxidant activity than 60% EtOH extract when evaluated by ABTS radical decolorization and antioxidant PF. The TBARS of water extracts and 60% EtOH extracts were shown as $0.29{\times}10^2{\mu}M\;and\;0.28{\times}10^2{\mu}M$, respectively, and were lower than control. ACE inhibitory activity in water extract (67.6% inhibition) was higher than that of 60% EtOH extract (46.7% inhibition) at $200{\mu}g/mL$. Water extracts had higher inhibitory activities on ${\alpha}$-amylase and ${\alpha}$-glucosidase than 60% EtOH extracts. The result suggests that the water extract from Rododendron mucronulatum Turcz. flowers will be useful as natural antioxidants and functional foods.

Association between Oral Health Behavior and Oral Health Status in Adolescent (청소년의 구강건강행태와 구강보건상태와의 관련요인)

  • Oh, Jungsuk
    • Journal of The Korean Society of Integrative Medicine
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    • v.5 no.4
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    • pp.103-112
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    • 2017
  • Purpose : This study was conducted to improve cognitive oral healthcare care by analyzing the correlation between oral health behavior and oral health status Korean adolescents. The subjects were 65,528 youths in 798 schools monitored in the Twelfth Korea Youth Risk Behavior Web-based Survey in 2016. Methods : The general characteristics consisted of 9 items including sex, grade, and academic performance. The academic performance and economic status were restructured into "upper, middle, lower". Subjective health perception and subjective oral health perception were reorganized as "health", "normal", "no health". The sub-areas of oral health behavior include five times of daily brushing during the day yesterday. The number of brushing times was "0", "1-2", "3", "more than 4" After lunch at school, brushing was restructured as "always," "sometimes," "not." The oral health status subscale consisted of 6 items including tooth breakage and toothache at the time of eating. Result : Tooth fracture(43.7 %), pain in mastication(43.7 %), tooth tingling(47.4 %), gum pain and bleeding(45 %), pain in buccal mucosa(43.8 %) and halitosis(46.6 %) were rare in adolescent having healthy oral health status cognitively(P<.001). Nosymptom adolescents without dental sealant showed low tooth fracture(0.64 times), pain in mastication(0.67 times), tooth tingling(0.59 times), gum pain and bleeding(0.84 times), pain in buccal mucosa(0.76 times), and halitosis(0.90 times). Nosymptom adolescents without scaling showed low tooth fracture(0.88 times), pain in mastication(1.03 times), tooth tingling(0.82 times), gum pain and bleeding(0.64 times), pain in buccal mucosa(0.70 times) and halitosis(0.82 times). Conclusion : This study revealed that oral health status is correlated with oral health behavior. Development of educational media and program, and aggressive promotion required to establish oral health Korean adolescent.

Evaluation of Seismic Performance in Relation to Beam-Panel Zone Strength Ratio of CFT Column to H-beam Endplate Connections (CFT 기둥-H형강보 엔드플레이트 접합부의 보-패널존 강도비에 따른 내진성능 평가)

  • Kim, Young Ju;Kim, Jae Keon;Oh, Young Suk;Moon, Tae Sup
    • Journal of Korean Society of Steel Construction
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    • v.12 no.6
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    • pp.769-777
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    • 2000
  • This paper presents the results of cyclic seismic performance in relation to beam-panel zone strength ratio of CFT Column to H-beam steel moment connections. Each test specimen consisted of $H-350{\times}175{\times}7{\times}11$ beam(SS400) and ${\boxe}-250{\times}250{\times}9$, ${\boxe}-250{\times}250{\times}12$ column(SPSR400). Main parameter is a column panel zone strength relative to beam strength. Energy absorption capacity available in the specimens ranged from 5.2 to 12.7(tm). If panel zone strength relative to beam strength is too strong or weak, the energy absorption capacity tended to be inferior. About steel moment-resisting frame, the test results of this experiment seem to support the investigation that permitting panel zone yielding shall be more advantageous to enhancing total seismic performance.

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Antimuscarine-like Action of Licorice Alkaloidal Fraction on Intestinal Smooth Muscle -Studies of Alkaloid of Glycyrrhiza glabra L. III- (감초(甘草) Alkaloidal Fraction 의 평활근(平滑筋)에 대(對)한 Acetylcholine 길항작용(拮抗作用) -감초 알카로이드에 관한 연구 (제 3 보)-)

  • Kim, Myung-Suk;Oh, Jin-Sup;Hong, Sa-Ack
    • The Korean Journal of Pharmacology
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    • v.5 no.2
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    • pp.121-127
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    • 1969
  • Antimuscarinic agent like antispasmodic actions of licorice alkaloidal fraction, obtained from the Glycyrrhiza glabra L., was compared with that of atropine quantitatively. For this purpose, the author calculated the kinetic constants and $ED_{50}$ for acetylcholine antagonism by these drugs on rat ileum and guinea-fig ileum longitudinal muscle according to Paton's theoretical equations describing the combination of an antagonist drug with its receptors. The results are as follows. 1. On rat ileum. a) Licorice alkaloidal fraction $K_1$ (association rate constant)=$4.078{\times}10^2\;(s^{-1}\;gm^{-1}\;ml)$ $K_2$ (dissociation rate constant)=$6.986{\times}10^{-4}\;(s^{-1})$ $ED_{50}(K_2/K_1)=1.772{\times}10^{-6}(gm/ml)$ b) Atropine $K_1=5.136{\times}10^6$, $K_2=7.714{\times}10^{-4}$, $ED_{50}=1.408{\times}10^{-10}$ 2. On guinea-pig ileum longitudinal muscle a) Licorice alkaloidal fraction $K_1=1.30{\times}10^2$, $K_2=1.25{\times}10^{-3}$ $ED_{50}=9.58{\times}10^{-6}$ b) Atropine $K_1=5.75{\times}10^6$, $K_2=1.54{\times}10^{-3}$ $ED_{50}=2.68{\times}10^{-10}$ Above results present that 1 r of licorice alkaloidal fraction has equal fotency of acetylcholine antagonism with $8.5{\times}10^{-5}r$ of atropine on rat ileum, $2.8{\times}10^{-5}r$ on guinea-pig ileum longitudinal muscle. This facts suggest that the site and numbers of licorice alkaloid receptors of guinea-pig ileum are different from that of rat ileum. Besides, it also gives a suggestion that licorice alkaloidal fraction may be a partial antagonist on guinea-pig ileum in this experimental conditions.

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Formation of Mixed Oxidants and Inactivation of E. coil by the Electrochemical Process using a Grid Shape Pt/Ti Electrode (Pt/Ti 격자형 평판 전극을 이용한 혼합 산화제 생성 및 E. coli 불활성화)

  • Jung, Yeon Jung;Oh, Byung Soo;Park, Sang Yeon;Baek, ko Woon;Kang, Joon-Wun
    • Journal of Korean Society on Water Environment
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    • v.22 no.5
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    • pp.851-855
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    • 2006
  • The aim of this study was to investigate characteristics of formation of mixed oxidants and some aspects of the performance of electrochemical process as an alternative disinfection strategy for water purification. The study of electrochemical process has shown free chlorine to be produced, but smaller amounts of stronger oxidants, such as ozone, hydrogen peroxide and OH radicals, were also generated. The formation of ozone and hydrogen peroxide increased with increasing electric conductivity, but was limited at conductivities greater than 0.6 mS/cm. Also, formation of OH radical was enhanced as electric conductivity was increased to 0.9 mS/cm and The stead-state concentrations of OH radical were calculated at $1.1{\sim}6.4{\times}10^{-14}M$. Using E. coti, inactivation kinetic studies were performed. With the exception of free chlorine, the role of mixed oxidants, especially OH radical, was investigated for enhancement of the inactivation rate.

Establishment of Optimum Condition for the Coagulation and Antimicrobial Activity of Konjac Jelly (곤약의 최적 응고 및 항미생물 활성을 위한 조건 확립)

  • Sim, Jae-In;Choi, Seon-Jeong;Jeong, Jae-Hyun;Choi, Ung-Kyu
    • Journal of the Korean Society of Food Culture
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    • v.29 no.5
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    • pp.415-420
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    • 2014
  • This study was conducted to establish optimum conditions for coagulation of konjac jelly as well as antimicrobial activity by concentration of $Ca(OH)_2$. Hardness, gumminess, and chewiness of konjac jelly increased according to concentration of konjac powder, the key material of konjac jelly. The highest sensory evaluation score was acquired with konjac jelly made with 3% konjac powder. A $Ca(OH)_2$ concentration of 0.4-0.6% as a coagulation agent was optimum for coagulation of konjac jelly. Further, sensory score was highest at a $Ca(OH)_2$ concentration of 0.6%. All populations of bacteria, yeast, and mold in konjac jelly were restrained by $Ca(OH)_2$ in a concentration- dependent manner. Furthermore, all tested microorganisms were strictly restrained at $1.0{\times}10^{-2}$ N of $Ca(OH)_2$.

Orthostatic Hypotension and Cognitive Function in Parkinson's Disease (파킨슨병에서 기립저혈압과 인지 기능의 관계)

  • Kim, Sooyoung;Lee, Juyoun;Oh, Eungseok;Sohn, Eun Hee;Lee, Ae Young
    • Journal of the Korean neurological association
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    • v.36 no.4
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    • pp.302-309
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    • 2018
  • Background: Although orthostatic hypotension (OH) and cognitive impairment (CI) are common non- motor symptoms of Parkinson's disease (PD), the relationship between OH and CI remains to be clarified. This study was aimed to investigate the relationship between OH and CI in PD. Methods: We recruited 192 patients who were diagnosed as PD based on the UK Brain Bank diagnostic criteria. The Hoehn & Yahr stages were ranged I to III and patients underwent extensive clinical evaluation, including brain magnetic resonance imaging (MRI) for cerebral white matter hyperintensity (WMH), tilt table test, the Korean version of Montreal Cognitive Assessments and the Korean version of Mini-Mental Status Examination in one month from the first clinic visit. The participants were divided into two groups according to the presence of OH (OH+ vs. OH-) and cognitive function (cognitive normal, CN vs. CI), respectively. Results: Significant relationship between OH and cognitive function (p=0.04) was found in our patients. The patients with OH+ had higher risk of CI by 2.6 times than that of OH- patients. Maximum heart rate change during tilt table test was correlated with cognitive function and white matter changes, whereas blood pressure change during tilt table test showed no correlation with those parameters. Conclusions: There was significant relationship between OH and CI in PD. Therefore, PD patients with either symptom may need periodic evaluation and proper management for OH and cognitive functions.

Gelation of Chitosan by Sol-Gel Method (졸-겔법에 의한 키토산의 겔화)

  • Kim, Tae-Young;Lee, Dong Il;Moon, Hee;Yang, Jai-Ho
    • Applied Chemistry for Engineering
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    • v.9 no.3
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    • pp.399-403
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    • 1998
  • The gelation characteristics of chitosan of different molecular weight were investigated in terms of concentration and temperature of alkari aqueous solution. The average molecular weights and the degrees of deacetylation of the chitosan used were $2.0{\times}10^5$, $5.2{\times}10^5$, $8.2{\times}10^5$ and 85%, respectively. Sodium hydroxide solution was used as a gelation agent. A simple diffusion model was applied to study the gelation rate. The diffusion coefficients of the gelation agent in the chitosan gel increased with increasing its concentration, temperature of the casting solution, and molecular weight of the chitosan.

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MDT-based Compression Scheme in H.264/AVC (H.264/AVC에서 다차원 변환 기반의 동영상 압축 방법)

  • Jo, J.K.;Lee, Y.S.;Jeong, S.Y.;Lee, J.H.;Oh, S.J.
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2009.11a
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    • pp.285-289
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    • 2009
  • 본 논문에서는 현재 비디오 코덱 표준인 H.264/AVC 에서 사용하고 있는 정수형 변환을 두 번 사용하는 다차원 변환 즉, MDT(Multi-Dimensional Transform) 을 제안한다. 제안하는 알고리듬은 H.264/AVC 7가지 인터 모드중에서 $16{\times}16$, $8{\times}16$, $16{\times}8$블록 모드에 적용된다. H.264/AVC에서 사용하는 정수형 변환을 $4{\times}4$블록 단위로 적용하고 인접하는 4개의 $4{\times}4$블록으로부터 같은 주파수 위치의 계수값을 모아서 16개의 $4{\times}1$벡터 변환을 추가로 수행하는 방법이다. MDT를 수행함으로써 H.264/AVC 표준에서 사용되는 변환이 가지는 예측오차를 유지하면서 공간적 중복도를 추가로 줄일 수 있다. MDT 된 계수들을 정수형으로 양자화하고 양자화된 계수값을 효율적으로 주사하는 방법을 제안하여 압축효율을 높였다. 제안된 알고리듬의 제안하는 MDT 기반 방법은 H.264/AVC High profile 표준보다 평균 3.00%의 비트 절감을 보였다.

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Effect of electron-beam irradiation on leakage current of AlGaN/GaN HEMTs on sapphire

  • Oh, Seung Kyu;Song, Chi Gyun;Jang, Taehoon;Kwak, Joon Seop
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.13 no.6
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    • pp.617-621
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    • 2013
  • This study examined the effect of electron-beam (E-beam) irradiation on the electrical properties of n-GaN, AlGaN and AlGN/GaN structures on sapphire substrates. E-beam irradiation resulted in a significant decrease in the gate leakage current of the n-GaN, AlGaN and HEMT structure from $4.0{\times}10^{-4}A$, $6.5{\times}10^{-5}A$, $2.7{\times}10^{-8}A$ to $7.7{\times}10^{-5}A$, $7.7{\times}10^{-6}A$, $4.7{\times}10^{-9}A$, respectively, at a drain voltage of -10V. Furthermore, we also investigated the effect of E-beam irradiation on the AlGaN surface in AlGaN/GaN heterostructure high electron mobility transistors(HEMTs). The results showed that the maximum drain current density of the AlGaN/GaN HEMTs with E-beam irradiation was greatly improved, when compared to that of the AlGaN/GaN HEMTs without E-beam irradiation. These results strongly suggest that E-beam irradiation is a promising method to reduce leakage current of AlGaN/GaN HEMTs on sapphire through the neutralization the trap.