• 대한한의학원전학회지
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• 제23권6호
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• pp.97-108
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• 2010

Salt is a vital inorganic substance to human body and is seasoning in food. It is an absolute alternating factor on fermented food. What's more, in the oriental medicine, it is widely used to raise the pharmacological effect as a component of a prescription when processing a medicine, and when taking the medicine. Though, Importance of salt is often unaware and it is not used in the right way. focusing on "東醫寶鑑 內景篇 Donguibogam-Naegyeong" I categorized the methods of salt's prescription, dose, processing, seasoning, etc. The contents were compared and studied as well. When salt is used as a medicine, It is used as a main medicine, complimentary(aid) medicine, Jjim-Jil(hot towel or bath etc), vomiting medicine and gargling water. when taking the salt water with other medicine, depending on the type of the medicine, boiled salt water, warm alcohol or salt water, mixing powder medicine with salt water etc The methods are diverse. The reason to process medicine with salt or salt water is to bring the pharmacological Qi(energy) down to increase remedial value. When processing a medicine, kneading dough with salt water and the case using food ingredient as medicine salt was used as seasoning. Kneaded mud with salt were used to cover medicine or on the outer surface. This proves that it prevents the dryness and helps the medicine cooked even. Like this, salt is vital and highly-valued medicine in the oriental medicine. learning the right method of using salt and if it were used properly It is considered that it would increase the Pharmacological effect.

• 대한한의학방제학회지
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• 제14권1호
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• pp.11-29
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• 2006

This report describes 71 studies related to the use of Radix Saposhnikoviae main blended prescription from Donguibogam. The following conclusion were reached through investigations on the prescriptions that use Radix Saposhnikoviae as a main ingredient. Prescriptions that Radix Saposhnikoviae was taken as a monarch drug are utilized for 20 therapeutic purposes, for example, eye disease, wind disease, head disease and Sang Han syndromes. In particular, 28.1% of prescriptions appear in the chapter of eye, and 25.3% of those appear in the chapter of head. Prescriptions that utilize Radix Saposhnikoviae as the main ingredient are used in the treatment of eye disease. paralysis and tetanus. Radix Saposhnikoviae is used in pathogenic factors such as wind. wind with cold. and used in pathology related to liver system. The dosage of Radix Saposhnikoviae in prescriptions is 7 li(about 0.26 gram) to 2.5 jeon(about 9.38 gram), however 1 jeon(about 3.75 gram) has been taken the most for clinical application. Bangpungtang is the most useful base prescription which use the Radix Saposhnikoviae as the main ingredient.

• 대한한의학방제학회지
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• 제28권1호
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• pp.15-27
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• 2020

Objectives : We selected three herb-combined remedies, Bigihwan (BGH), Daechilgitang (DCGT) and Mokwhyangbinranghwan (MHBRH), through Donguibogam text-mining analysis, and evaluated their anti-cancer effects on human hepatocellular carcinoma Hep3B cells. Methods : Cytotoxicity was assessed by an MTT assay. Apoptosis rate, autophagy and ROS level were detected by flow cytometry. The autophagy was also observed by Cyto-ID staining fluorescence microscopy. The expression of autophagy, mitophagy and pexophagy regulatory proteins was detected by Western blot analysis. Results : BGH showed the strongest effect among the three prescriptions in inhibiting Hep3B cell viability, which was associated with the induction of apoptosis and autophagy. Autophagy blockers improved cell viability and reduced apoptosis after BGH and DCGT treatments, indicating that autophagy by these prescriptions enhanced Hep3B cells against their cytotoxicity. However, MHBRH enhanced the reduction of cell viability and apoptosis by autophagy blockers. Induction of autophagy by BGH treatment was associated with mitophagy due to mitochondrial dysfunction than DCGT and MHBRH-treated cells. In addition, induction of apoptosis by BGH treatment was ROS-dependent and showed the possibility of pexophagy involvement. Conclusion : Although further studies need to be conducted to study the efficacy and mechanism of accurate anticancer activity, the present results will serve as important sources of understanding the mechanism of action of herbal remedies prescribed for liver disease as documented in Donguibogam.

• 대한한의학원전학회지
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• 제31권4호
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• pp.17-26
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• 2018

Objectives : This paper studies Zhushang, which is the name of a disease found in excavated books. Zhusang is the first disease listed in Wushierbingfang, which is a medical textbook excavated at Mawangdui, and Zhusang was followed by diseases such as Jinshang and Renshang. The paper studies what disease each of the word is refering to in terms of graphonomy, and compared the difference of their treatment from other classical texts. Methods : The scope of the study of this paper includes the excavated textbooks that seem to contain any disease related to Zhusang, and the two major text books of these are Wushierbingfang and Wuweihandaiyijian. Then Shennongbencao jing, which is the one of the earlier books on herbology, and Bencao gangmu, which was written based on the former, wer used to make comparisons. Parts in Donguibogam that seem to be related to the parts in the excavated texts were also compared. The study was done by first performing historical research on the names of the diseases in the excavated books, and compared them with the contents of the classical texts. Results : The Zhushang discovered in Wushierbingfang refers to wounds caused by metal or wood. It was interesting how they created a word for diseases depending on the cause. Only Jinshang is found in Wuweihandaiyijian, and the fact that different causes gave way to different names tells us that they had corresponding treatment. The categorization of Zhushang, Jinshang, and Renshang is corresponded better in Donguibogam than Chinese medical books.

• 동의생리병리학회지
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• 제19권4호
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• pp.848-859
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• 2005

The following conclusions are drawn, through studying of referring literature, of contents of the prescription and of clinical applications in Hyungsang Medicine. Insamyangyung-tang(인삼양영탕) was appeared first in Taepunghyemin-whajegugbang(태평혜민화제국방) which was written by Jin and others at Song Dynasty. This prescription is applied to senility and long lasting weakness, little strength of spleen and lung(비폐기허), and insufficiency of blood. The Insamyangyung-tang is composed of medical stuffs which Rhizoma Cnidii is taken out from Sipjiendaebotang and Pericarpium Citri Nobilis, Fructus Schizandrae, Radix Polygalae are added to it. This prescription is used in China up to the present. In korea, according to Donguibogam, Rhizoma Cnidii and Poria are taken out from Sipjiendaebotang and Pericarpium Citri Nobilis, Fructus Schizandrae, Radix Polygalae are added to it, and Ramulus Cinnamomi is changed to Cortex Cinnamomi, and also Radix Ledebouriellae is newly added to it. This is reorganized to fit for Korean physical conditions and to be useful for deficiency of blood, and also to be efficacious for coming and going of chillness and fever and running with sweat due to weakness of Liver. In the point of view of Hyunsang medicine, Insamyangyung-tang is applied to shapes and symptoms as follows : This prescription becomes more efficacious to women than to men. At the age of fifties when liver grows weak it effects a cure. It takes effect to the shape of going easily into the deficiency of blood, that is, to the Hyul Kwa with an oval face. It effects a cure on the man who has wrinkles on the bridge of the nose, who has marks of being choked up on the central area between two brows, or who has distinctive size of eyes and nose. It is efficacious against symptoms which are to be exhausted, to be weak, to lose flesh, to be coming and going of chillness and fever and running with sweat.

• 동의생리병리학회지
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• 제20권3호
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• pp.516-521
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• 2006

The following conclusions are drawn from Hyungsang medicinal review on th globs hystericus through Donguibogam and other literatures. The globs hystericus appears in the throat and the epigastric region. It is a subjective sensation as if a plum pit is stick in the throat and is compressed, usually ac companied by stuffiness in chest, depression, nausea, and hiccup. But the throat is not marked with redness and swelling. Because Gi stagnation due to seven emotions is the main cause, the globs hystericus is usually followed by Seven Gi injuries, Pain and depressive syndrome due to disorder of Gi, palpitation due to fright, continuous violent palpitation, Gi phlegm, precordial pain with palpitation, epigastric pain due to seven emotions, cough and dyspnea due to disorder of Gi, and six kinds of stagnations. When head and body or chest and abdomen is compared to heaven and earth, the blockage of Gi between heaven and earth is common to the persons with the following charcteristics in Hyungsang; Dam type rather than Bankwang type, Gi type and Shin type rather than deer type and fish type, Taeum and Yangmyeong meridian types out of six meridian types, manly women, womanly man, too long or short neck, and signs of stagnation between the eyebrows. The globus hystericus needs, distinguishing from aphonia, acute tonsilitis, goiter, and pectorial pain with stuffiness. The affected area of aphonia and acute tonsilitis is the throat but they are not cause by the disturbance of seven emotions. Goiter can be distinguished by the changes in the appearance of neck. Even though the symptoms are similar, globus hystericus is caused by the stagnation of Gi, but the pectorial pain with stuffiness, by the insufficiency of the Heart blood. The general prescriptions are Chilgitang, Sachiltang, Gamisachiltang, Gamiijintang, and Sinihwan.

• 사상체질의학회지
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• 제21권2호
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• pp.72-78
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• 2009

1. Objectives : This paper was written in order to understand the origin and changes of Galgeunhaegi-tang. 2. Methods : We analysis Galgeunhaegi-tang through pathology and new prescription in "Donguibogam(東醫寶鑑)", "Chobongwon(草本卷)", "Gabobon(甲午本)" and "Sinchukbon(辛丑本)" of "Dongyi Suse Bowon". 3. Results and Conclusions : We can find the first origin of Galgeunhaegi-tang in "Sinchukbon(辛丑本)" in "Donguibogam(東醫寶鑑)" which invelves Galgeunhaegi-tang in the categories of pestilence(瘟疫) and Yangmyeonggyeongbyeong(陽明經病). Also, we can find the origin in Jugoeng(朱肱)' Jojung-tang. Seungeumgalgeun-tang in the "Chobongwon(草本卷)" developed by a Galgeunhaegi-tang of "Gabobon(甲午本)", and Galgeunnabokja-tang in the "Chobongwon(草本卷)" developed by a Galgeunhaegi-tang of "Sinchukbon(辛丑本)". It is considered that Galgeunhaegi-tang of "Gabobon(甲午本)" solves heat depression(鬱熱), due to not throwing off, by using Galgeun(葛根) and Daehwang(大黃), and accompanied dryness(燥) by using Hangin(杏仁) and Sanjoin(酸棗仁) which moisten dryness(燥). It is considered that Galgeunhaegi-tang of "Sinchukbon(辛丑本)" solves heat depression(鬱熱) by using Galgeun(葛根) and accompanied dryness(燥) by using Gobon(藁本) which sets free dryness(燥).

• 한국의사학회지
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• 제30권1호
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• pp.51-59
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• 2017

Shihosamul-tang (柴胡四物湯, Bupleurum Four Substances Decoction) is a very effective and widely utilized prescription in Korean medicine. However, there has not been a clinical example written in the classical literature of Korean medicine that deals with Shihosamul-tang and the delicate and changeable clinical use of Shihosamul-tang remains unknown. This study tries, for the first time, to show the clinical practice of Shihosamul-tang through review of KyungBoSinPyun (輕寶新篇). KyungBoSinPyun is a medical book containing 143 case records in the tradition of the East Asian practice of describing clinical encounters and the therapies employed. This study examines eight examples of case records within KyungBoSinPyun highlighting use of Shihosamul-tang. The purpose is to understand how Shihosamul-tang is applied in clinical practice compared to the description of Shihosamul-tang in Donguibogam (東醫寶鑑). Different descriptions about the symptoms and transformation methods of the prescription have been found in the eight examples of Shihosamul-tang case records contained in KyungBoSinPyun. This paper concludes that the difference between clinical practice and a typical description in medical books should be overcome by medical virtuosity and the potential for change for each clinical case, which is gained when seeing beyond the text of medical books.

• 대한한의학원전학회지
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• 제20권1호
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• pp.103-111
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• 2007

1. "Regulation for about kind of formularies of Korean traditional herbaland preparation method"(Ministry of Health and Welfare No. 1995-15, 95. 3. 15) and "Regulation for review safety and efficacy of drugs. Article 2. 1 Clause 10." should revise "Sasanguihak(四象醫學)" by "Donguisusebowon(東醫壽世保元)" that is the name of book. 2. "Regulation for review safety and efficacy of drugs. Article 2. 1 Clause 10." was defining 'The 11 established formularies of Korean traditional herbal medicine volumes' "Donguisusebowon" that is defined as "The 11 established formularies of Korean traditional herbal medicine volumes" is "Susebowon(壽世保元)" that the Ming period Gong jung-hyun writes. Otherwise, mistake that "Donguisusebowon" of Lee Jema(李濟馬) was recorded 2 times occurs. Therefore, "Susebowon" of "The 11 established formularies of Korean traditional herbal medicine volumes" is that "Susebowon" of the Ming period Gong Jung-hyun writes 3. "yaksungga(藥性歌)" is nonbook in "The 11 established formularies of Korean traditional herbal medicine volumes" and should be erase. Because basis is ambiguous. 4. "The 11 established formularies of Korean traditional herbal medicine volumes" must revise by 10 kinds in "Regulation for about kind of formularies of Korean traditional herbaland preparation method" and "Regulation for review safety and efficacy of drugs. Article 2." The kinds should be revised by "Donguibogam(東醫寶鑑)", "jejungsinpyeon(濟衆新編)", "Euihakipmoon(醫學入門)", "kyungakjeonse(景岳全書)", "Susebowon", "Bonchogangmok(本草鋼目)", "Bangyakhappyeon(方樂合編)", "Hyangyakjipseongbang(鄕樂集成方)", "Gwangjebigeup" and "Donguisusebowon".

• 한국의사학회지
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• 제34권2호
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• pp.109-116
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• 2021

Uihagipmun was a medical book published by Leecheon during the Ming Dynasty of China in the 16th century and was introduced to Korea during the mid-Joseon Period. This text greatly influenced the establishment of the Donguibogam, an important work in Korean medicine. This study confirms that many medical professionals of the Joseon Dynasty loved the Uihagipmun and that the Uihagipmun was very important during the Joseon Dynasty. Since then, the status of the Uihagipmun in Korean medicine continued to be emphasized by Korean medicine doctors throughout the Japanese colonial era. The translation of the Uihagipmun began in the 1970s as part of the classical Korean medicine translation project under the leadership of the Korean medicine group "Hanbanguiuhoe". However, due to a lack of funds, the translation was delayed and the first edition was published on October 10, 1974. Writings of those who led the translation at that time show that the translation of the Uihagipmun thought that the exact translation of the Uihagipmun in Korean medicine could lead to the scientific and modernization of Korean medicine. Therefore, Gugyeok pyeonjuuihagipmun should not be regarded as a mere translation, but as a medical book of important value in Korean medical history.