• Journal of the Korean Society of Radiology
• /
• v.8 no.3
• /
• pp.123-136
• /
• 2014

In this paper, we study to classify molecular imaging and applications to predict future. Molecular imaging in vivo at the cellular level and the molecular level changes taking place to be imaged, that is molecular cell biology and imaging technology combined with the development of the new field. Molecular imaging is used fluorescence, bioluminescence, SPECT, PET, MRI, Ultrasound and other imaging technologies. That is applied to monitoring of gene therapy, cell tracking and monitoring of cell therapy, antibody imaging, drug development, molecular interaction picture, the near-infrared fluorescence imaging of cancer using fluorescence, bacteria using tumor-targeting imaging, therapeutic early assessment, prediction and therapy. The future of molecular imaging would be developed through fused interdisciplinary research and mutual cooperation, which molecular cell biology, genetics, chemistry, physics, computer science, biomedical engineering, nuclear medicine, radiology, clinical medicine, etc. The advent of molecular imaging will be possible to early diagnosis and personalized treatment of disease in the future.

• The Korean Journal of Applied Statistics
• /
• v.28 no.6
• /
• pp.1075-1091
• /
• 2015

This paper reviews the developments of econometric analysis and seeks a statistical applicability to current economic phenomena. During the last half century, economic analysis has progressed continuously, analyzing and predicting a broad variety of economic phenomena. In the center of this progress lies the remarkable contribution of econometrics and mathematical statistics. New economic research environment has been recently created via developments of IT and the spread of internet and SNSs. Economic phenomena has become increasingly complicated along with more volatile and sophisticated economic analysis. In that context, it can be suggested that there is a need to move beyond current economic paradigms and adapt new approaches such as complex theory and econophysics, all of which posits as a challenge for econometrics and statistics.

• Journal of the Korean Society for information Management
• /
• v.26 no.2
• /
• pp.195-210
• /
• 2009

This study explores knowledge structures of science and technology disciplines using a cocitation analysis of journal subject categories with the publication data of a science & technology oriented university in Korea. References cited in the articles published by the faculty of the university were analyzed to produce MDS maps and network centralities. For the whole university research domain, six clusters were created including clusters of Biology related subjects, Medicine related subjects, Chemistry plus Engineering subjects, and multidisciplinary sciences plus other subjects of multidisciplinary nature. It was found that subjects of multidisciplinary nature and Biology related subjects function as central nodes in knowledge communication network in science and technology. Same analysis procedure was applied to two natural science disciplines and another two engineering disciplines to present knowledge structures of the departmental research domains.

• The Korean Journal of Applied Statistics
• /
• v.29 no.5
• /
• pp.859-872
• /
• 2016

Land cover classification is an important tool for preventing natural disasters, collecting environmental information, and monitoring natural resources. Hyperspectral imaging is widely used for this task thanks to sufficient spectral information. However, the curse of dimensionality, spatiotemporal variability, and lack of labeled data make it difficult to classify the land cover correctly. We propose a novel classification framework for land cover classification of hyperspectral data based on convolutional neural networks. The proposed framework naturally incorporates full spectral features with the information from neighboring pixels and has advantages over existing methods that require additional feature extraction or pre-processing steps. Empirical evaluation results show that the proposed framework provides good generalization power with classification accuracies better than (or comparable to) the most advanced existing classifiers.

• Progress in Medical Physics
• /
• v.25 no.2
• /
• pp.116-121
• /
• 2014

Next future, The bio technology will be a rapidly developing. This paper is the scattering beam measurement of the red blood cell (RBC) and the fabrication of the micro cell biochip using the bio micro electro mechanical system (Bio-MEMS) process technology. The Major process method of Bio-MEMS technology was used the buffered oxide etchant (BOE), electro chemical discharge (ECD) and ultraviolet sensitive adhesives (UVSA). All experiments were the 10 times according to the process conditions. The experiment and research are required the ultraviolet expose, the micro fluid current, the cell control and the measurement of the output voltage Vpp (peak to peak) waveform by scattering angles. The transmitting and receiving of the laser beam was used the single mode optical fiber. The principles of the optical properties are as follows. The red blood cells were injected into the micro channel. The single mode optical fiber was inserting in the guide channel. The He-Ne laser beam was focusing in the single mode optical fiber. The transmission He-Ne laser beam is irradiating to the red blood cells. The manufactured guide channel consists of the four inputs and the four outputs. The red blood cell was allowed with the cylinder pump. The output voltage Vpp waveform of the scattering beam was measured with a photo detector. The receiving angle of the output optical fiber is $0^{\circ}$, $5^{\circ}$, $10^{\circ}$, $15^{\circ}$. The magnitude of the output voltage Vpp waveform was measured in the decrease according to increase of the reception angles. The difference of the output voltage Vpp waveform is due differences of the light transmittance of the red blood cells.

• Progress in Medical Physics
• /
• v.20 no.4
• /
• pp.199-207
• /
• 2009

It is important to initialize Image Plate (IP) completely for removing residual latent image by sodium lamp for reliability and repeatability of computed radiography (CR) system. The purpose of this study was to evaluate latent images of computed radiography (CR) images respect to delay time after erasure of foregone latent image and its effect, and erasure level. Erasure thoroughness for CR acceptance test from American Association of Physicist in Medicine (AAPM) Report 93 (2006) was also evaluated. Measurements were made on a CR (Agfa CR 25; Agfa, BELGIUM) system. Chest postero-anterior (PA), Hand PA, L-spine lateral radiographs were chosen for evaluation. Chest phantom (3D-torso; CIRS, USA) was used for Chest PA and L-spine lateral radiography. For Hand PA radiography, projections was done without phantom. Except Hand PA radiographs, noise was increased with delay time, and ghost image was appeared on overexposed area. Effect of delay after erasure on latent image was not seen on naked eye, but standard deviation (SD) of pixel value on overexposed area was relatively higher than that of other areas. On Hand PA and Chest PA radiographs, noise were not occurred by adjustment of erasure level. On L-spine lateral images at lower erasure level than standard level, noise including ghost image were occurred because of high tube current. Erasure thoroughness of CR system in our department was to be proved by these evaluation. The results of this study could be used as a baseline for IP initialization and reliability of CR images.

• Journal of the Korean Data and Information Science Society
• /
• v.27 no.2
• /
• pp.381-394
• /
• 2016

Graphical model represents conditional dependencies between variables as a graph with nodes and edges. It is widely used in various fields including physics, economics, and biology to describe complex association. Conditional dependencies can be estimated from a inverse covariance matrix, where zero off-diagonal elements denote conditional independence of corresponding variables. This paper proposes a efficient BCDR (block coordinate descent with random permutation) algorithm using graphics processing units and random permutation for the CONCORD (convex correlation selection method) based on the BCD (block coordinate descent) algorithm, which estimates a inverse covariance matrix based on pseudo-likelihood. We conduct numerical studies for two network structures to demonstrate the efficiency of the proposed algorithm for the CONCORD in terms of computation times.

• Journal of The Korean Association For Science Education
• /
• v.9 no.1
• /
• pp.53-67
• /
• 1989

General Physics CAI Program was developed for university science and engineering student. The program was restricted in the field of mechanics and was mainly aimed for individual tutorial. This project was supported by Government. Department of Education, physics attending their general physics classes in university. The program was written in BASIC and constructed by frame, 4 professors and 6 graduate students were involved in the project. Summary of this study is as follows. 1. The theory of CAI was illuminated from a new point of view to enhance usefullness of CAI. Also the structure of frame type CAI was studied. 2. The program was developed as follows 1) The program consisted of main program, pretest routine, tutorial routine, final test routine, and several other routines for program control. Whole program was written in BASIC. 2) 20 problems for pretest, 90 problems and subsequent hints and solutions for tutorial, 20 problems for final test were developed. 3) According to student's pretest result, tutorial course was routed through several different courses which contain different number of problems 4) The expected rate of achievment for final test was set to 75%. 5) Data of students response to problems including number of tries and time used were recorded for the purpose of achievment analisys 3. 22 students went through whole course and the results were as follows. 1) Pretest marks were widly distributed from 20 points to 100. It means that achievement of high school physics course were not enough. 2) Throughout tutorial course, students who had got higher mark in pretest answered correctly in the first trial at a higher rate of 78 %. Overall rate of correct answer in the second trial was distributed appropriatly. 3) Average mark of final test was 78.8 points, rather a higher rate of achievement than expected. This means that the program was constructed well.

• 한국해양학회지
• /
• v.5 no.2
• /
• pp.41-51
• /
• 1970

Periodic characters of water temperature in the regions of the Mishima and the Okinoshima were derived through the analysis of the five days interval data during 1914 to 1970 mainly. In terms of ten days mean temperatures, annual variation function of the Mishima region, Korea Strait, is F($\theta_d$)=17.45-5.34 cos $\theta_d$-3.77 sin $\theta_d$+0.62 sin $2\theta_d$ -0.52 sin $3\theta_d$, where $\theta_d$=$\frac{\pi}{18}$(d-2), d is the order of ten days period 1 to 36. And in the region of Okinoshima, Tsushima Strait, we find F($\theta_d$)=18.88-5.39 cos $\theta_d$-3.60 sin $\theta_d$+0.52 sin $2\theta_d$. The annual mean temperature is 17.4$^{\circ}C$ in the Mishima region, 18.9$^{\circ}C$ in the Okinoshima region, and the amplitudes of annual variation functions are 7$^{\circ}C$ in both regions with minimum temperature in the middle ten days of February, maximum in the middle ten days of August. The long term variations of surface water temperature with 12 5 years period were observed in the annual mean temperature, monthly mean temperatures and the fixed day temperatures of every year. In addition to these, relatively short term variations were also found significant periods of 3 years, 4 years and 2 years, respectively.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
• /
• v.19 no.4
• /
• pp.405-414
• /
• 2001

Plate tectonics is a dominant paradigm in modern geophysics. Because of its geological mechanism, Korea has a possibility of earthquake according to plate motion. Besides the disaster of earthquake grows rapidly, the importance of recognition for earthquake has been emphasized. This study attempts to decide crustal movement parameters with GPS data, analysed baseline after processing data with GIPSY-OASIS II S/W, observed from 6 stations in and around the Korean peninsula, and obtained from selected 11 stations in Korea. As a results, maximum shear strain was $0.04{\mu}/yr$ and the mean azimuth of the maximum compression axes$(A_{z2})$ is estimated as $97.75^{\circ}$ in and around the Korean peninsula. The average rate of the maximum shear strain($({\gamma}_max)$) is $0.17{\mu}/yr$. The mean azimuth of the maximum compression axes$(A_{z2})$ is estimated as $70.25^{\circ}$ in Korea. Such a pattern of strain distribution is harmonious with that of seismic activity in Korea both historically as well as today.