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http://dx.doi.org/10.11002/kjfp.2015.22.2.290

Antioxidant and α-glucosidase inhibition activity of seaweed extracts  

Kim, Jin-Hak (Department of Food Science and Technology, Catholic University of Daegu)
Kang, Hye-Min (Department of Food Science and Technology, Catholic University of Daegu)
Lee, Shin-Ho (Department of Food Science and Technology, Catholic University of Daegu)
Lee, Ju-Young (Department of Food Science and Technology, Catholic University of Daegu)
Park, La-Young (Department of Food Science and Technology, Catholic University of Daegu)
Publication Information
Food Science and Preservation / v.22, no.2, 2015 , pp. 290-296 More about this Journal
Abstract
The antioxidant and ${\alpha}$-glucosidase inhibition activities of 10 kinds of seaweeds Ecklonia cava (EC), Ecklonia stolonifera (ES), Eisenia bicyclis (EB), Capsosiphon fulvescens (CF), Sargassum fulvellum (SF), Undaria pinnatifida (UP), Sargassum thunbergii (ST), Codium fragile (CFr), Hizikia fusiformis (HF), and Enteromorpha prolifera (EP) were investigated. Among all the tested seaweed extracts, the total polyphenol and flavonoid contents of the EB extract were highest 150.81 mg/g and 77.02 mg/g, respectively. The DPPH and ABTS radical scavenging abilities of the EB ethanol extract (1 mg/mL) were 86.26% and 99.71%, respectively, and its SOD-like activity and reducing power were 21.34% and 1.710 ($OD_{700}$). The ${\alpha}$-glucosidase inhibition activities of the EC, EB, and ST were above 98% at the 0.1 mg/mL concentration. These results suggest that seaweed extracts effectively prevent the what of antioxidants and decrease the blood glucose level, and may be used to develop various functional products.
Keywords
seaweed extract; antioxidant; ${\alpha}$-glucosidase; physiological functionalities;
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1 Cowburn R, Hardy J, Roberts P, Briggs R (1988) Regional distribution of pre- and postsynaptic glutamatergic function in Alzheimer's disease. Brain Res, 452, 403-407   DOI
2 Reiter RJ (1995) Oxidative process and antioxidative defense mechanism in the aging brain. FASEB J, 9, 526-533
3 Cai L, Kang YJ (2001) Oxidative stress and diabetic cardiomyopathy: a brief review. Cardiovasc Toxicol, 1, 181-193   DOI
4 Drews G, Krippeit-Drews P, Dufer M (2010) Oxidative stress and beta-cell dysfunction. Pflugers Arch, 460, 703-718   DOI
5 Ahn BS, Kim JW, Kim HT, Lee SD, Lee KW (2010) Antioxidant effects of Hovenia dulcis in the streptozotocininduced diabetic rats. J Veterinary Clinics, 27, 366-373
6 Branen AL (1975) Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene. J Am Oil Chem Soc, 52, 59-63   DOI
7 Mooradian AD, Thurman JE (1999) Drug therapy of postprandial hyperglycaemia. Drugs, 57, 19-29
8 Joo DS, Lee JK, Choi YS, Cho SY, Je YK, Choi JW (2003) Effect of sea tangle oligosaccharide drink on serum and hepatic lipids in rats fed a hyperlipidemic diet. J Korean Soc Food Sci Nutr, 32, 1364-1369   DOI
9 Choi IW, Kim SU, Seo DC, Kang BH, Sohn BK, Rim YS, Heo JS, Cho JS (2005) Biosorption of heavy metals biomass of seaweeds, Laminaria species, Ecklonia stolonifera, Gelidium amansii, and Undaria pinnatifida. Korean J Environ Agri, 24, 370-378   DOI
10 Oh JK, Shin YO, Sohn HS, Seo RM (2003) Effect of functional food including seaweeds extracts supplementation on hematological variables and antioxidant system. Korean J Physical Education, 42, 895-903
11 Kong CS, Um YR, Lee JI, Kim YA, Lee JS, Seo YW (2008) Inhibition effects of extracts and its solvent fractions isolated from Limonium tetragonum on growth of human cancer cells. Korean J Biotechnol Bioeng, 23, 177-182
12 Lim JH, Jung KS, Lee JS, Jung ES, Kim DK, Kim YS, Kim YW, Park DH (2008) The study on antimicrobial and antifungal activity of the wild seaweeds of Jeju island. J Soc Cosmet Sci Korean, 34, 201-207
13 Cha MH, Kim YK (2008) Analysis of consumption values of a seaweed functional food. Korean J Food Culture, 23, 462-468
14 Lee EH, Ham J, Ahn HR, Kim MC, Kim CY, Pan CH, Um BH, Jung SH (2009) Inhibitory effects of the compounds isolated from Sargassum yezoense on ${\alpha}$-glucosidase and oxidative stress. Korean J Pharmacogn, 40, 150-154
15 Folin O, Denis W (1912) On phosphotungsticphosphomolybdic compounds as color reagents. J Biol Chem, 12, 239-249
16 Abdel-Hameed ESS (2008) Total phenolic contents and free radical scavenging activity of certain Egyptian Ficus species leaf samples. Food Chem, 114, 1271-1277
17 Blois MS (1958) Antioxidant determination by the use of a stable free radical. Nature, 181, 1199-1200   DOI
18 Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C (1999) Antioxidant activity applying an improved ABTS radial cation decolorization assay. Free Radic Biol Med, 26, 1231-1237   DOI
19 Marklund S, Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem, 47, 469-474   DOI
20 Oyaizu M (1986) Studies on products of browning reaction prepared from glucose amine. Jpn J Nutr, 44, 307-315   DOI
21 Buege JA, Aust SD (1978) Microsomal lipid peroxidation. Method Enzymol, 52, 302-310   DOI
22 Kim KY, Nam KA, Kurihara H, Kim SM (2008) Potent ${\alpha}$-glucosidase inhibitors purified from the red alga Grateloupia elliptica. Phytochem, 69, 2820-2825   DOI
23 Ahn SM, Hong YK, Kwon GS, Sohn HY (2010) Evaluation of in-vitro anticoagulation activity of 35 different seaweed extracts. J Life Sci, 20, 1640-1647   DOI
24 Middleton E, Kandaswami C (1994) Potential healthpromoting properties of citrus flavonoids. Food Technol, 48, 115-119
25 Seo YH, Kim IJ, Yie AS, Min HK (1999) Electron donating ability and contents of phenolic compounds, tocopherols and carotenoids in waxy corn (Zea mays L.). Korean J Food Sci Technol, 31, 581-585
26 Nakamura K, Ogasawara Y, Endou K, Fujimori S, Koyama M, Akano H (2010) Phenolic compounds responsible for the superoxide dismutase-like activity in high-brix apple vinegar. J Agric Food Chem, 58, 10124-10132   DOI
27 Choudhary RK, Swarnkar PL (2011) Antioxidant activity of phenolic and flavonoid compounds in some medical plants of India. Nat Prod Res, 25, 1101-1109   DOI
28 Osawa T (1994) Novel natural antioxidant for utilization in food and biological system. In : Postharvest Biochemistry of Plant Food Material in the Tropics, Uritani I, Garcia VV, Mendoza EM(editor), Japan Scientific Societies Press, Tokyo, Japan, p 241-251
29 Lee BB, Park SR, Han CS, Han DY, Park EJ, Park HR, Lee SC (2008) Antioxidant activity and inhibition activity against ${\alpha}$-amylase and ${\alpha}$-glucosidase of Viola mandshurica extracts. J Korean Soc Food Sci Nutr, 37, 405-409   DOI
30 Cojocaru IM, Cojocaru M, Musuroi C, Botezat M, Lazar L, Druta A (2004) Lipid peroxidation and catalase in diabetes mellitus with and without ischemic stroke. Rom J Intern Med, 42, 423-429
31 Kim HY, Lim SH, Park YH, Ham HJ, Lee KJ, Park DS, Kim KH, Kim S (2011) Screening of ${\alpha}$-amylase, ${\alpha}$-glucosidase and lipase inhibitory activity with Gangwon-do wild plants extracts. J Korean Soc Food Sci Nutr, 40, 308-315   DOI   ScienceOn
32 Xu ML, Wang L, Hu JH, Wang MH (2009) Antioxidant and ${\alpha}$-glucosidase inhibitory activities of some wild vegetable extracts. J Agric Food Chem, 47, 4121-4125