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http://dx.doi.org/10.11002/kjfp.2011.18.3.407

Effect of Alcohol Detoxification Beverage that Contained Bulnesia sarmienti on Alcohol-metabolizing Enzymes and Antioxidant Enzyme Activities  

Lim, Ae-Kyung (Daegu Bio Industry Center)
Jung, Mee-Jung (Department of Food Science & nutrition, Pukyong National University)
Lee, Jae-Wook (Daegu Bio Industry Center)
Hong, Joo-Heon (Department of Food Science and Technology, Catholic University of Daegu)
Kim, Kil-Soo (College of Veterinare Medicine, Kyungpook National University)
Jung, Seok-Bang (Lucky medicine company of limited)
Kim, Dae-Ik (Daegu Bio Industry Center)
Publication Information
Food Science and Preservation / v.18, no.3, 2011 , pp. 407-413 More about this Journal
Abstract
This study was carried out to investigate the effect of a beverage that contained Bulnesia sarmienti(BSP, 2.5%) on rats to which alcohol was administered. The treatment of the BSP group reduced the serum alcohol concentration to 52%, compared to 47% in the positive control(PC) group. Similar pattell1s were observed in the enhancement of alcohol dehydrogenase(ADH), acetaldehyde dehydrogenase(ALDH), alkaline phosphate(ALP), alanine aminotransferase(ALT), asparate aminotransferase(AST), total cholesterol(CHOL), ${\gamma}$-glutamyltrasferase(GGT), glucose(GLU), total bilirubin, and total protein(TP) in the serum. Also, in the BSP group, the lipoxidase(LPO), glutathion-S-transferase(GST), XO, catalase(CAT), and superoxide dismutase(SOD) were significantly reduced, compared to the CO and PC groups in the liver. The glutathione(GSH) activity increased in the BSP group, though. These results indicate that Bulnesia sarmienti extract can enhance alcohol metabolization activity.
Keywords
Bulnesia sarmienti; alcohol dehydrogenase; acetaldehyde dehydrogenase; alkaline phosphate; alanine aminotransferase; asparate aminotransferase;
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Times Cited By KSCI : 2  (Citation Analysis)
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