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Effects of Perilla frutescens L. on anti-oxidant and anti-inflammation activity  

Son, Hyeong-U (Department of Food Science & Technology, Kyungpook National University)
Heo, Jin-Chul (Department of Food & Bio-Industry Research Institute, Kyungpook National University)
Seo, Myung-Sun (SongKwangMaeWon Co., Ltd.)
Lee, Sang-Han (Department of Food Science & Technology, Kyungpook National University)
Publication Information
Food Science and Preservation / v.17, no.5, 2010 , pp. 757-761 More about this Journal
Abstract
It is recognized that Perilla frutescens L. (PfL) are useful for various diseases, including allergic disorders. To evaluate whether the PfL extract have potential in alleviating oxidant and inflammatory process, some in vitro antioxidant assays and in vivo DNFB-induced atopic assay were investigated. Extracts of PfL have potent anti-oxidant activity by DPPH or FRAP assay. By treatment of high temperature / high pressure extraction process of PfL seed, the activity was increased. Using a mouse animal model, we found that PfL extract reduces ear thickness and epithelial thickening and infiltration of immune cells inhibition. Collectively, the present results suggest that PfL can be used as an antioxidant and/or anti-inflammatory biomaterial, that should be proved to evaluate on mechanistic study and development of functional food.
Keywords
Perilla frutescens L.; anti-oxidant; anti-inflammation; atopy mouse model;
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Times Cited By KSCI : 4  (Citation Analysis)
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