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A Tyrosinase Inhibitor Isolated from the Seeds of Eriobotrya japonica  

Kim, Tae-Hoon (Department of Herbal Medicinal Pharmacology, Daegu Haany University)
Shin, Seung-Ryeul (Faculty of Herbal Food & Nutrition, Daegu Haany University)
Kim, Tae-Wan (Faculty of Food Science & Biotechnology, Andong National University)
Lee, In-Chul (Senior Industry Cluster Agency, Youngdong University)
Park, Moon-Young (Subtropical Fruit Crops Experiment Station, Jeonnam Agricultural Research & Extension Services)
Jo, Cheo-Run (Department of Animal Science and Biotechnology, Chungnam National University)
Publication Information
Food Science and Preservation / v.16, no.3, 2009 , pp. 435-441 More about this Journal
Abstract
Activity-guided isolation from the ethylacetate (EtOAc)-soluble portion of a methanolic extract of the seeds of Eriobotrya japonica, using several bioassays, led to the isolation and identification of six phenolic compounds of previously known structure: benzaldehyde (1), chlorogenic acid (2), caffeic acid (3), benzoic acid (4), ferulic acid (5), and amygdalin (6). Of these, benzaldehyde (1) exhibited tyrosinase inhibitory activity in a bioassay. In addition, chlorogenic acid (2) and caffeic acid (3) were found to have strong antioxidative effects on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and superoxide dismutase (SOD)-like activity.
Keywords
Eriobotrya japonica; tyrosinase inhibition; antioxidant; phenolic compounds;
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