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Biological Activities of Crude Polysaccharides and Crude Saponins from Salicornia herbacea  

Jung, Sung-Hee (Department of Food and Nutrition, Sunchon National University)
Park, Kyung-Uk (Department of Food and Nutrition, Sunchon National University)
Kim, Jae-Yong (Department of Food Science and Technology, Kyungpook National University)
Park, Chae-Kyu (Division of Ginseng Research, KT&G Central Research Institute)
Choi, Kap-Seong (Department of Food Science and Technology, Sunchon National University)
Seo, Kwon-Il (Department of Food and Nutrition, Sunchon National University)
Publication Information
Food Science and Preservation / v.16, no.1, 2009 , pp. 109-114 More about this Journal
Abstract
To develop Salicornia herbacea as a functional food material, crude polysaccharides and saponins were isolated from 80% ethanolic extracts of Salicornia herbacea using Diaion HP-20 column chromatography, and biological activities including anti-oxidation, anti-proliferation of cancer cells, and immune activities were investigated. The hydrogen-donating properties of crude polysaccharides and saponins were above 20% at $500{\mu}g/mL$ concentration. The reducing power of fractions increased in a dose-dependent manner. Crude polysaccharides and saponins at $500{\mu}g/mL$ inhibited more than 20% and 50% of proliferation by PC-3 and HT-29 human cancer cells, respectively. The anti-oxidative and anti-cancer properties of crude saponins were higher than those of crude polysaccharides. Also, proliferation in spleen cells and (nitric oxide) NO production in RAW264.7 macrophages treated with crude polysaccharides increased in a dose-dependent manner compared with the untreated control cells. However, crude saponins at concentration greater than $500{\mu}g/mL$ resulted in decreases in immune activities. Immune activities of crude polysaccharide were greater than those of crude saponins. These results indicate that Salicornia herbacea may be used as functional food materials.
Keywords
Salicornia herbacea; crude polysaccharides; crude saponins; biological activity;
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