1 |
Musi N, Hirshman MF, Nygren J, Svanfeldt M, Bavenholm P, Rooyackers O, Zhou G, Williamson JM, Ljunqvist O, Efendic S, Moller DE, Thorell A, Goodyear LJ. 2002. Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes 51: 2074-2081.
DOI
|
2 |
Carling D. 2004. The AMP-activated protein kinase cascade -a unifying system for energy control. Trends Biochem Sci 29: 18-24.
DOI
|
3 |
Kuo YH, Lin CH, Shih CC. 2015. Ergostatrien--ol from Antrodia camphorata inhibits diabetes and hyperlipidemia in high-fat-diet treated mice via regulation of hepatic related genes, glucose transporter 4, and AMP-activated protein kinase phosphorylation. J Agric Food Chem 63: 2479-2489.
DOI
|
4 |
Lu J, Wu DM, Zheng YL, Hu B, Cheng W, Zhang ZF, Shan Q. 2011. Ursolic acid improves high fat diet-induced cognitive impairments by blocking endoplasmic reticulum stress and kinase /nuclear factor--mediated inflammatory pathways in mice. Brain Behav Immun 25: 1658-1667.
DOI
|
5 |
Reynolds TH IV, Cinquino N, Anthony M, Phelps CB, Zachary Berk E. 2009. Insulin resistance without elevated mammalian target of rapamycin complex 1 activity in muscles of mice fed a high-fat diet. J Appl Physiol 107: 1479-1485.
DOI
|
6 |
Dasuri K, Zhang L, Kim SOKF, Bruce-Keller AJ, Keller JN. 2016. Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain. Biochim Biophys Acta 1862: 274-283.
DOI
|
7 |
Gao Y, Zhang M, Wu T, Xu M, Cai H, Zhang Z. 2015. Effects of D-pinitol on insulin resistance through the PI3K/Akt signaling pathway in type 2 diabetes mellitus rats. J Agric Food Chem 63: 6019-6026.
DOI
|
8 |
Choi CS, Park SW. 2002. The mechanism of development of insulin resistance in type 2 diabetes mellitus. Korean J Med 63: 613-625.
|
9 |
Jo YH, Choi KM, Liu Q, Kim SB, Ji HJ, Kim M, Shin SK, Do SG, Shin E, Jung G, Yoo HS, Hwang BY, Lee MK. 2015. Anti-obesity effect of 6,8-diprenylgenistein, an isoflavonoid of Cudrania tricuspidata fruits in high-fat diet-induced obese mice. Nutrients 7: 10480-10490.
DOI
|
10 |
Ministry for Health, Welfare and Family Affairs; Korea Centers for Disease Control and Prevention. 2014. National Health Nutrition Examination Survey Report. Korea Centers for Disease Control and Prevention, Cheongju, Korea.
|
11 |
Tanabe K, Nakamura S, Omagari K, Oku T. 2011. Repeated ingestion of the leaf extract from Morus alba reduces insulin resistance in KK-Ay mice. Nutr Res 31: 848-854.
DOI
|
12 |
Kaushik G, Satya S, Khandelwal RK, Naik SN. 2010. Commonly consumed Indian plant food materials in the management of diabetes mellitus. Diabetes Metab Syndr 4: 21-40.
DOI
|
13 |
Van Gaal L, Scheen A. 2015. Weight management in type 2 diabetes: current and emerging approaches to treatment. Diabetes Care 38: 1161-1172.
DOI
|
14 |
Publishing Committee of Pharmacognosy. 2000. Pharmacognosy. Dongmyongsa, Seoul, Korea. p 257.
|
15 |
Jang MJ, Rhee SJ. 2004. Hypoglycemic effects of pills made of mulberry leaves and silkworm powder in streptozotocininduced diabetic rats. J Korean Soc Food Sci Nutr 33: 1611-1617.
DOI
|
16 |
Krol E, Jeszka-Skowron M, Krejpcio Z, Flaczyk E, Wojciak RW. 2016. The effects of supplementary mulberry leaf (Morus alba) extracts on the trace element status (Fe, Zn and Cu) in relation to diabetes management and antioxidant indices in diabetic rats. Biol Trace Elem Res 174: 158-165.
DOI
|
17 |
Ann JY, Eo H, Lim Y. 2015. Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice. Genes Nutr 10: 46.
DOI
|
18 |
Wu T, Tang Q, Gao Z, Yu Z, Song H, Zheng X, Chen W. 2013. Blueberry and mulberry juice prevent obesity development in C57BL/6 mice. PLoS One 8: e77585.
DOI
|
19 |
Park JH, Lee KW, Sung KS, Kim SS, Cho KD, Lee BH, Han CK. 2012. Effect of diets with Job's tears and Cudrania tricuspidata leaf mixed-powder supplements on body fat and serum lipid levels in rats fed a high-fat diet. J Korean Soc Food Sci Nutr 47: 943-949.
|
20 |
Andallu B, Suryakantham V, Lakshmi Srikanthi B, Reddy GK. 2001. Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes. Clin Chim Acta 314: 47-53.
DOI
|
21 |
Kim OK, Nam DE, Jun W, Lee J. 2015. Cudrania tricuspidata water extract improved obesity-induced hepatic insulin resistance in db/db mice by suppressing ER stress and inflammation. Food Nutr Res 59: 29165.
DOI
|
22 |
Folch J, Lees M, Sloane Stanley GH. 1957. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226: 497-509.
|
23 |
Omodeo Sale F, Marchesini S, Fishman PH, Berra B. 1984. A sensitive enzymatic assay for determination of cholesterol in lipid extracts. Anal Biochem 142: 347-350.
DOI
|
24 |
Lee JS, Lee MK, Ha TY, Bok SH, Park HM, Jeong KS, Woo MN, Do GM, Yeo JY, Choi MS. 2006. Supplementation of whole persimmon leaf improves lipid profiles and suppresses body weight gain in rats fed high-fat diet. Food Chem Toxicol 44: 1875-1883.
DOI
|
25 |
Park SH, Jang MJ, Hong JH, Rhee SJ, Choi KH, Park MR. 2007. Effects of mulberry leaf extract feeding on lipid status of rats fed high cholesterol diets. J Korean Soc Food Sci Nutr 36: 43-50.
DOI
|
26 |
Kim AJ, Kim SY, Choi MK, Kim MH, Han MR, Chung KS. 2005. Effects of mulberry leaves powder on lipid metabolism in high cholesterol-fed rats. Korean J Food Sci Technol 37: 636-641.
|
27 |
Cha JY, Kim HJ, Cho YS. 2000. Effects of water-soluble extract from leaves of Morus alba and Cudrania tricuspidata on the lipid peroxidation in tissues of rats. J Korean Soc Food Sci Nutr 29: 531-536.
|
28 |
Do SG, Park JH, Nam H, Kim JB, Lee JY, Oh YS, Suh JG. 2012. Silk fibroin hydrolysate exerts an anti-diabetic effect by increasing pancreatic cell mass in C57BL/KsJdb/db mice. J Vet Sci 13: 339-344.
DOI
|
29 |
Cho YS, Shon MY, Lee MK. 2007. Lipid-lowering action of powder and water extract of mulberry leaves in C57BL/6 mice fed high-fat diet. J Korean Soc Food Sci Nutr 36: 405-410.
DOI
|
30 |
Lim HH, Yang SJ, Kim Y, Lee M, Lim Y. 2013. Combined treatment of mulberry leaf and fruit extract ameliorates obesity-related inflammation and oxidative stress in high fat diet-induced obese mice. J Med Food 16: 673-680.
DOI
|
31 |
Kim SH, Kang JS, Lee SJ, Chung YJ. 2008. Antidiabetic effect of Korean red ginseng by puffing process in streptozotocin-induced diabetic rats. J Korean Soc Food Sci Nutr 37: 701-707.
DOI
|
32 |
O'Meara NMG, Devery RAM, Owens D, Collins PB, Johnson AH, Tomkin GH. 1990. Cholesterol metabolism in alloxan-induced diabetic rabbits. Diabetes 39: 626-633.
DOI
|
33 |
Nikkila EA, Kekki M. 1973. Plasma triglyceride transport kinetics in diabetes mellitus. Metabolism 22: 1-22.
DOI
|
34 |
Biddinger SB, Almind K, Miyazaki M, Kokkotou E, Ntambi JM, Kahn CR. 2005. Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome. Diabetes 54: 1314-1323.
DOI
|
35 |
Konner AC, Bruning JC. 2012. Selective insulin and leptin resistance in metabolic disorders. Cell Metab 16: 144-152.
DOI
|
36 |
Guo J, Jou W, Gavrilova O, Hall KD. 2009. Persistent dietinduced obesity in male C57BL/6 mice resulting from temporary obesigenic diets. PLoS One 4: e5370.
DOI
|
37 |
Chiu CY, Chan IL, Yang TH, Liu SH, Chiang MT. 2015. Supplementation of chitosan alleviates high-fat diet-enhanced lipogenesis in rats via adenosine monophosphate (AMP)-activated protein kinase activation and inhibition of lipogenesis-associated genes. J Agric Food Chem 63: 2979-2988.
DOI
|
38 |
Yang X, Yang L, Zheng H. 2010. Hypolipidemic and antioxidant effects of mulberry (Morus alba L.) fruit in hyperlipidaemia rats. Food Chem Toxicol 48: 2374-2379.
DOI
|
39 |
Holt RIG, Cockram C, Flyvbjerg A, Goldstein BJ. 2010. Textbook of diabetes. 4th ed. Wiley-Blackwell, West Sussex, UK. p 56-60.
|
40 |
Kulkarni RN, Bruning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. 1999. Tissue-specific knockout of the insulin receptor in pancreatic cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 96: 329-339.
DOI
|
41 |
Harrington LS, Findlay GM, Lamb RF. 2005. Restraining PI3K: mTOR signalling goes back to the membrane. Trends Biochem Sci 30: 35-42.
DOI
|
42 |
Lee YS, Cha BY, Saito K, Yamakawa H, Choi SS, Yamaguchi K, Yonezawa T, Teruya T, Nagai K, Woo JT. 2010. Nobiletin improves hyperglycemia and insulin resistance in obese diabetic ob/ob mice. Biochem Pharmcol 79: 1674-1683.
DOI
|
43 |
Chakraborty A, Koldobskiy MA, Bello NT, Maxwell M, Potter JJ, Juluri KR, Maag D, Kim S, Huang AS, Dailey MJ, Saleh M, Snowman AM, Moran TH, Mezey E, Snyder SH. 2010. Inositol pyrophosphates inhibit Akt signaling, regulate insulin sensitivity and weight gain. Cell 143: 897-910.
DOI
|