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http://dx.doi.org/10.3746/jkfn.2017.46.1.010

Effects of Mixed Scutellaria baicalensis Extracts as Natural Preservative on Efficacy and Storage of Lactic Acid-Fermented Garlic Extract  

Lee, Hee-Seop (Department of Food and Biotechnology, Korea University)
Lee, Sun-Jin (Department of Food and Biotechnology, Korea University)
Sohn, Johann (Food R&D Center, SKbioland Co., Ltd.)
Yu, Heui-Jong (Food R&D Center, SKbioland Co., Ltd.)
Cho, Hong-Yon (Department of Food and Biotechnology, Korea University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.46, no.1, 2017 , pp. 10-17 More about this Journal
Abstract
The natural preservative "complex Scutellaria baicalensis extract (BHC)" contains Scutellaria baicalensis, Glycyrrhiza uralensis (liquorice), Zizyphus jujube (jujube), and Astragalus propinquus (milk vetch root). BHC has been used as a natural preservative for more than 10 years to increase storage duration and quality of food with strong antibacterial activity. BHC has been added into functional foods as a subsidiary ingredient. However, no studies have been performed to test whether or not BHC affects the activity of main functional ingredients. In this study, we tested whether or not BHC has any effect on the hepatoprotective activity of lactic acid-fermented garlic extract (LAFGE) when formulated in a clinical test supplement. $H_2O_2-induced$ oxidative damage in HepG2 cells was not attenuated by BHC, indicating that BHC had no influence on the protective effect of LAFGE against oxidative damage. Furthermore, BHC had no effect on the hepatoprotective effect of LAFGE against acetaminophen-induced acute liver injury in rats, as indicated by no changes in alanine transaminase and aspartate transaminase levels. In conclusion, BHC, formulated in the clinical test supplement with LAFGE, had no effect on hepatoprotective activity, indicating BHC could be considered as a suitable natural preservative for liquefied functional food materials.
Keywords
lactic acid-fermented garlic; mixed Scutellaria baicalensis extracts; liver-protective; efficacy; storage;
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