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http://dx.doi.org/10.3746/jkfn.2013.42.4.556

Effects of Water-Soluble Polysaccharides from Tott on Lipid Absorption and Animal Body Weight  

Baek, Gu (Dept. of Pharmaceutical Science, Gachon University)
Goo, Bon Geun (Dept. of Pharmaceutical Science, Gachon University)
Ahn, Byung Jae (Jeonnam Marine Bio-industry Center)
Park, Jae Kweon (Dept. of Life Science, Gachon University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.42, no.4, 2013 , pp. 556-562 More about this Journal
Abstract
We examined the anti-obesity effects of water-soluble polysaccharides (WSP-A) extracted from the seaweed Hijikia fusiforme (Tott in Korean). The extracted alginate-like polysaccharide (verified by FT-IR and HPAEC-PAD analysis) was examined in a lipase inhibition assay and animal experiments. WSP-A inhibited lipase up to 30%, with over 80% of the initial activity retained until the 1 hour reaction in vitro. There was a 30% loss in the rate of weight gain in rats fed a high-fat diet. WSP-A therefore seems to serve as a healthy weight loss agent by inhibiting lipases, thus preventing the absorption of fat in the body.
Keywords
seaweed; Tott (Hijikia fusiforme); polysaccharides; anti-obesity; lipase inhibitor;
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