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http://dx.doi.org/10.3746/jkfn.2013.42.2.168

The Effects of Extraction Conditions on the Antioxidative Effects of Extracts from Campbell Early and Muscat Bailey A Grapevine Leaves  

Choi, Soo-Kyong (Dept. of Food and Nutrition, Yeungnam University)
Yu, Qi-Ming (Dept. of Food and Nutrition, Yeungnam University)
Lim, Eun-Ji (Dept. of Food and Nutrition, Yeungnam University)
Seo, Jung-Sook (Dept. of Food and Nutrition, Yeungnam University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.42, no.2, 2013 , pp. 168-174 More about this Journal
Abstract
We investigated the physiological activities of extracts from Campbell Early and Muscat Bailey A (MBA) grapevine leaves. Total phenol and flavonoid contents were highest in ethanol extracts from MBA grapevine leaves compared to extracts from Campbell Early grapevine leaves. Specific polyphenols higher in ethanol extracts from MBA grapevine leaves include gallic acid, epicatechin, caffeic acid, naringin, and resveratrol. Resveratrol content from MBA grapevine leaves increased when extracted for more than two hours in ethanol and water. The hydroxyl radical scavenging ability of ethanol extracts was higher than the water extract from both strains of grapevine leaves. DPPH and total antioxidants were highest in ethanol extracts from MBA grapevine leaves among the other extracts. Therefore, these results suggest that ethanol extracts from MBA grapevine leaves are a highly valuable resource for the development of natural functional foods.
Keywords
grapevine leaves; resveratrol; polyphenol; antioxidant; extraction time;
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1 Iacopini P, Baldi M, Storchi P, Sebastiani L. 2008. Catechin, epicatechin, quercetin, rutin and resveratrol in red grape: content, in vitro antioxidant activity and interactions. J Food Compos Anal 21: 589-598.   DOI   ScienceOn
2 Dercks W, Creasy LL. 1989. The significance of stilbene phytoalexins in the Plasmopara viticola-grapevine interaction. Physiol Mol Plant Pathol 34: 189-202.   DOI
3 O'Byme DJ, Devaraj S, Grundy SM, Jialal I. 2002. Comparison of the antioxidant effects of Concord grape juice flavonoids and ${\alpha}$-tocopherol on markers of oxidative stress in the healthy adults. Am J Clin Nutr 76: 1367-1374.
4 Aggarwal BB, Chanda M, Shishodia S. 2006. Sources and chemistry of resveratrol. In Resveratrol in Health and Disease. Aggarwal BB, Shishodia S, eds. CRC Press, New York, NY, USA. p 17-32.
5 Bishayee A. 2009. Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials. Cancer Prev Res (Phila) 2: 409-418.   DOI   ScienceOn
6 Bai Y, Mao QQ, Qin J, Zheng XY, Wang YB, Yang K, Shen HF, Xie LP. 2010. Resveratrol induces apoptosis and cell cycle arrest of human T24 bladder cancer cells in vitro and inhibits tumor growth in vivo. Cancer Sci 101: 488-493.   DOI   ScienceOn
7 Lee SM, Yang H, Tartar DM, Gao B, Luo X, Ye SQ, Zaghouani H, Fang D. 2011. Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes. Diabetologia 54: 1136-1146.   DOI
8 Azorin-Ortuno M, Yanez-Gascon MJ, Pallares FJ, Rivera J, Gonzalez-Sarrias A, Larrosa M, Vallejo F, Garcia-Conesa MT, Tomas-Barberan F, Espín JC. 2012. A dietary resveratrol-rich grape extract prevents the developing of atherosclerotic lesions in the aorta of pigs fed an atherogenic diet. J Agric Food Chem 60: 5609-5620.   DOI   ScienceOn
9 Kang JH, Kim KA, Han JS. 2004. Korean diet and obesity. J Korean Soc Study Obes 13: 34-41.
10 Jeong HS, Song YM, Lee KS. 2007. Aging and health care expenditure. Korean J Health Econ Policy 13: 95-116.
11 Kennedy A, Overman A, Lapoint K, Hopkins R, West T, Chuang CC, Martinez K, Bell D, McIntosh M. 2009. Conjugated linoleic acid-mediated inflammation and insulin resistance in human adipocytes are attenuated by resveratrol. J Lipid Res 50: 225-232.   DOI
12 Baxter RA. 2008. Anti-aging properties of resveratrol: review and report of a potent new antioxidant skin care formulation. J Cosmet Dermatol 7: 2-7.   DOI   ScienceOn
13 Cho CH, Kim SY, Yoo GJ, Son MH, Park KH, Lim BL, Kim DC, Chae HJ. 2008. Resveratrol extraction from grape fruit stem and its antioxidant activity. J Korean Soc Appl Biol Chem 51: 11-16.   과학기술학회마을
14 Lee NR, Choi SJ. 2009. Content of resveratrol in different parts of various grape cultivars. Korean J Food Preserv 16: 959-964.
15 Lee OS, Moon SW, Kim EJ, Kang BS. 2008. Studies on physicochemical and sensory characteristics of new grape leaves tea by roasting treatment. Int J Integrative Alter Med 4: 17-24.
16 Chang SW, Shin NS, Song JH, Kim HJ, Lee KY, Rho YT. 2009. Production of high-level polyphenol powders from young grape leaves. Korean J Food Preserv 16: 714-718.
17 Simopoulos AP. 2004. The traditional diet of Greece and cancer. Eur J Cancer Prev 13: 219-230.   DOI   ScienceOn
18 Choi SY, Lee Y, Lee P, Kim KT. 2011. Comparison of the antioxidative effects and content of anthocyanin and phenolic compounds in different varieties of Vitis vinifera ethanol extract. J Food Sci Nutr 16: 24-28.   과학기술학회마을   DOI   ScienceOn
19 Delmas D, Jannin B, Latruffe N. 2005. Resveratrol: preventing properties against vascular alterations and ageing. Mol Nutr Food Res 49: 377-395.   DOI   ScienceOn
20 Su HC, Hung LM, Chen JK. 2006. Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin- induced diabetic rats. Am J Physiol Endocrinol Metab 290: E1339-E1346.   DOI   ScienceOn
21 Zhang XH, Choi SK, Seo JS. 2009. Effect of dietary grape pomace on lipid oxidation and related enzyme activities in rats fed high fat diet. Korean J Nutr 42: 415-422.   과학기술학회마을   DOI   ScienceOn
22 Lee SJ, Choi SK, Seo JS. 2009. Grape skin improves antioxidant capacity in rats fed a high fat diet. Nutr Res Pract 3: 279-285.   DOI   ScienceOn
23 Pari L, Suresh A. 2008. Effect of grape (Vitis vinifera L.) leaves extract on alcohol induced oxidative stress in rats. Food Chem Toxicol 46: 1627-1634.   DOI   ScienceOn
24 Moreno MI, Isla MI, Sampietro AR, Vattuone MA. 2000. Comparison of the free radical-scavenging activity of propolis from several regions of Argentina. J Ethnopharmacol 71: 109-114.   DOI   ScienceOn
25 Kang YH, Park YK, Oh SR, Moon KD. 1995. Studies on the physiological functionality of pine needle and mugwort extracts. Korean J Food Sci Technol 27: 978-984.   과학기술학회마을
26 Korea Agro-Fisheries & Food Trade Corporation. 2011. Grape. In Agricultural Products Consumption Actual Condition. Seoul, Korea. Vol 2, p 655-666.
27 Singleton VL, Rossi Jr JA. 1965. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am J Enol Vitic 16: 144-158.
28 Taware PB, Dhumal KN, Oulkar DP, Patil SH, Banerjee K. 2010. Phenolic alterations in grape leaves, berries and wines due to foliar and cluster powdery mildew infections. Int J Pharma Bio Sci 1: 1-14.
29 Gutteridge JM. 1984. Reactivity of hydroxyl and hydroxyl- like radicals discriminated by release of thiobarbituric acid-reactive material from deoxy sugars, nucleosides and benzoate. Biochem J 224: 761-767.   DOI
30 Blois MS. 1958. Antioxidant determinations by the use of a stable free radical. Nature 181: 1199-1200.   DOI   ScienceOn
31 Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. 1999. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 26: 1231-1237.   DOI   ScienceOn
32 Lee J, Lee SR. 1994. Some physiological activity of phenolic substances in plant foods. Korean J Food Sci Techol 26: 317-323.   과학기술학회마을
33 Bogs J, Downey MO, Harvey JS, Ashton AR, Tanner GJ, Robinson SP. 2005. Proanthocyanidin synthesis and expression of genes encoding leucoanthocyanidin reductase and anthocyanidin reductase in developing grape berries and grapevine leaves. Plant Physiol 139: 652-663.   DOI   ScienceOn
34 Ahn MS, Kim HJ, Seo MS. 2007. A study on the antioxidative and antimicrobial activities of the citrus Unshju peel extracts. Korean J Food Culture 22: 454-461.   과학기술학회마을
35 Oh YS, Lee JH, Yoon SH, Oh CH, Choi DS, Choe E, Jung MY. 2008. Characterization and quantification of anthocyanins in grape juices obtained from the grapes cultivated in Korea by HPLC/DAD, HPLC/MS, and HPLC/MS/MS. J Food Sci 73: C378-C389.
36 Choi Y, Lee SM, Chun J, Lee HB, Lee J. 2006. Influence of heat treatment on the antioxidant activities and polyphenolic compounds of Shiitake (Lentinus edodes) mushroom. Food Chem 99: 381-387.   DOI   ScienceOn
37 Ahn JB. 2006. Development of red wine containing high level of trans-resvertrol with domestic grape. Food Engineering Progress 10: 226-232.
38 Wang W, Tang K, Yang HR, Wen PF, Zhang P, Wang HL, Huang WD. 2010. Distribution of resveratrol and stilbene synthase in young grape plant (Vitis vinifera L. cv. Cabernet Sauvignon) and the effect of UV-C on its accumulation. Plant Physiol Biochem 48: 142-152.   DOI   ScienceOn
39 Yusuke O, Kyohei T, Hirosane I. 2006. Composition for bleaching food. JP 18296394.
40 Yoshihide H. 2009. Grape-leaves tea and method for producing the same. JP 21165410.