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http://dx.doi.org/10.3746/jkfn.2010.39.5.677

Effect of Young Phragmites communis Leaves Powder on Lipid Metabolism and Erythrocyte Antioxidant Enzyme Activities in High-Fat Diet Fed Mice  

Lee, Jin (Dept. of Food and Nutrition, Sunchon National University)
Jeong, Joo-Yong (Dept. of Nutrition Education, Graduate School of Education, Sunchon National University)
Cho, Young-Sook (Dept. of Food and Nutrition, Sunchon National University)
Park, Seok-Kyu (Dept. of Food and Nutrition, Sunchon National University)
Kim, Kwang-Jin (Gardaenara Agricultural Co. Ltd., Sunchon National University)
Kim, Myung-Joo (Faculty of Hotel Cuisine, Daegu Polytechnic College)
Lee, Mi-Kyung (Dept. of Food and Nutrition, Sunchon National University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.39, no.5, 2010 , pp. 677-683 More about this Journal
Abstract
This study investigated the effect of young Phragmites communis (Pc) leaves on lipid profiles, lipid metabolism and erythrocyte antioxidant defense system in high-fat diet fed mice. Three groups of mice were fed different diets for 8 weeks: normal diet (Normal), high-fat diet (High-fat; 37% calories from fat) and high-fat diet supplemented with 1% Pc (wt/wt, HF-Pc). Body weight, daily food intake and energy intake tended to decrease by Pc supplement in high-fat fed mice. Pc supplementation significantly lowered plasma triglyceride and total cholesterol concentrations compared to the high-fat control group. Pc also lowered hepatic and heart cholesterol contents, whereas it significantly increased fecal excretion of triglyceride and cholesterol compared to the high-fat control group. Pc significantly inhibited fatty acid synthase, 3-hydroxy-3-methylglutaryl CoA reductase and acyl-CoA:cholesterol acyltransferase activities compared to the high-fat control group. Erythrocyte superoxide dismutase and catalase activities were also significantly higher in the high-fat group than in the normal group, however Pc supplementation reversed these changes. The Pc supplementation significantly lowered erythrocyte lipid peroxidation level compared to the high-fat control group. Accordingly, these results suggest that Pc improves lipid metabolism and erythrocyte antioxidant defense system in high-fat diet fed mice.
Keywords
Phragmites communis leaves; lipid profile; lipid metabolism; antioxidant defense system; erythrocyte;
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Times Cited By KSCI : 5  (Citation Analysis)
Times Cited By SCOPUS : 2
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