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http://dx.doi.org/10.3746/jkfn.2010.39.2.237

Effect of Antioxidative Vitamin Supplementation on Mineral Contents in the Hair and Autistic Related Behaviors in Autistic Children  

Song, Won-Young (School of Food Science, International University of Korea)
Hong, Jung-Hee (Samsung Biomedical Research Institute)
Park, Eun-Ju (Dept. of Food Science and Nutrition, Kyungnam University)
Lee, Han-Woo (School of Social Welfare, International University of Korea)
Choi, Jeong-Hwa (School of Food Science, International University of Korea)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.39, no.2, 2010 , pp. 237-243 More about this Journal
Abstract
This study was investigated the effect of antioxidative vitamin supplementation ($\beta$-carotene 175 mg, vitamin C 200 mg, vitamin E 33.5 mg) for 12 weeks on antioxidant status and autistic related behaviors in autistic children. The antioxidative vitamin-supplemented children had significantly lower concentrations of toxic mineral, such as cadmium (Cd), mercury (Hg) and lead (Pb) in hair, while they had higher concentration of antioxidant minerals (Se, Zn, Fe) in hair. Antioxidant vitamin supplementation for 12 weeks reduced free radical while it increased the hair levels of serotonin compared to the beginning of the study. Additionally, antioxidative vitamin supplementation resulted in significant improvement in social age. These results indicate that the consumption of antioxidative vitamin supplementation for 12 weeks in autistic children may increase plasma antioxidant mineral concentration, resulting in reduced toxic mineral and free radical and improved autistic behavior.
Keywords
autistic children; antioxidative vitamin; toxic mineral; antioxidant mineral; free radical;
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Times Cited By KSCI : 3  (Citation Analysis)
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