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http://dx.doi.org/10.3746/jkfn.2010.39.1.071

Effect of Water Extracts from Phellinus linteus on Lipid Composition and Antioxidative System in Rats Fed High Fat High Cholesterol Diet  

Song, Won-Young (School of Food Science, International University of Korea)
Sung, Byoung-Hun (Kumhwangbio., LTD)
Kang, Sin-Kwon (School of Food Science, International University of Korea)
Choi, Jeong-Hwa (School of Food Science, International University of Korea)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.39, no.1, 2010 , pp. 71-77 More about this Journal
Abstract
The purpose of the present study was to examine the effect of water extracts from Phellinus linteus on lipid composition and antioxidative system in rats fed high fat high cholesterol diet. Rats were divided into four experimental groups which are composed of normal diet group, high fat high cholesterol diet group, high fat high cholesterol diet with 50 mg/kg b.w water extracts from Phellinus linteus supplemented group (PA group), high fat high cholesterol diet with 100 mg/kg b.w water extracts from Phellinus linteus supplemented group (PB group). The serum TG and cholesterol contents of the water extracts from Phellinus linteus supplemented groups (PA and PB groups) were decreased compared to the high fat high cholesterol diet group. The serum HDL-cholesterol contents of the water extracts from Phellinus linteus supplemented groups were increased compared to the high fat high cholesterol diet group. The serum LDL-cholesterol and AI of the water extracts from Phellinus linteus supplemented groups were significantly decreased compared to the high fat high cholesterol diet group. Supplementation of water extracts from Phellinus linteus groups (PA and PB groups) resulted in increased activities of superoxide dismutase. Hepatic glutathione peroxidase (GSH-px) were increased compared to the high fat high cholesterol diet group. TBARS values in liver and plasma were reduced in water extracts from Phellinus linteus supplemented groups. These result suggest that supplementation of water extracts from Phellinus linteus may have a pronounced impact on lipid composition and antioxidative system in the rats fed high fat high cholesterol diet.
Keywords
Phellinus linteus; lipid composition; antioxidative system; cholesterol;
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