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http://dx.doi.org/10.3746/jkfn.2009.38.8.1032

The Macro Mineral Contents in High Fat Diet-Induced Obese Rats Fed Various Amounts of Zinc  

Kim, Hyun-Sook (Dept. of Food and Nutrition, Sookmyung Women's University)
Sung, Chung-Ja (Dept. of Food and Nutrition, Sookmyung Women's University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.38, no.8, 2009 , pp. 1032-1036 More about this Journal
Abstract
This study was conducted to investigate the effect of dietary zinc on macro mineral contents of high fat diet-induced obese rats. The obese group was divided into three groups by zinc levels of diet, such as low (50% requirement), adequate (100%) and high (200%) levels of dietary zinc. The calcium, magnesium, sodium and potassium contents in serum and organs were measured by ICP. There were no significant differences in the food intake, weight gain and feed efficiency ratio among the different dietary zinc levels. Also, the liver, kidney and spleen weight did not show the significant differences among each level of dietary zinc. However, serum sodium and potassium concentrations in the low zinc diet group were significantly higher than in the other diet groups. In high zinc diet group, the calcium contents of liver was significantly higher than in the other diet groups, magnesium and potassium contents of liver were higher than in the low zinc diet group. The sodium contents of liver and magnesium and potassium contents of spleen were significantly lower in the low zinc diet group than in the other diet groups. In conclusion, the macro mineral contents of serum, liver and spleen in obese rats were changed by dietary zinc levels. Especially, the low zinc diet group considerably changed of macro mineral contents in organs. Therefore, it may be suggested that adequate level of dietary zinc in obese individuals should be required.
Keywords
obese; zinc; macro mineral; adequate level;
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1 Lind L, Lithell H, Hvarfner A, Pollar T, Ljunghall S. 1993. On the relationships between mineral metabolism, obesity and fat distribution. Eur J Clin Invest 23: 307-310   DOI   ScienceOn
2 Kenney ML, Failla ML, Smith JC. 1987. Influence of genetic obesity in tissue concentrations of zinc, copper, manganese and iron in mice. J Nutr 116: 1432-1441
3 Wallwork JC, Fosmire GJ, Sandstead HH. 1981. Effect of zinc deficiency on appetite and plasma amino acid concentrations in the rat. Br J Nutr 45: 127-136   DOI   ScienceOn
4 Seaborn CD, Stoecker BJ. 1989. Effect of starch, sucrose, fructose and glucose on chromium absorption and tissue concentrations in obese and lean mice. J Nutr 119: 1444-1451   DOI
5 Gupta RP, Verma PC, Sadana JR, Gupta VK. 1989. Effect of experimental zinc deficiency and repletion on sodium, potassium, copper and iron concentrations in guinea-pigs. Br J Nutr 62: 407-414   DOI   ScienceOn
6 Luque-Diaz MJ, Dean-Guelbenzu M, Culebras-Poza JM. 1982. Changes in the metabolism of iron, copper and zinc in obesity. Rev Esp Fisiol 38S: 155-158
7 Larsson B. 1990. Obesity, fat distribution and cardiovascular disease. In Progress in Obese Research. Oomura Y, ed. John Libbey & Comp. Ltd., London, UK. p 375-379
8 Chen MD, Lin PY, Lin WH, Cheng V. 1988. Zinc in hair and serum of obese individuals in Taiwan. Am J Clin Nutr 48: 1307-1309   DOI
9 Luque-Diaz MJ, Dean-Guelbenzu M, Culebras-Poza JM. 1982. Changes in the metabolism of iron, copper and zinc in obesity. Rev Esp Fisiol 38S: 155-158
10 Foldes J, Shih MS, Levy J. 1992. Bone structure and calcium metabolism in obese Zucker rats. Int J Obese Relat Metab Disorb 16: 95-102
11 Chandra RK, Kutty KM. 1997. Immuocompetence in obesity. Acta Paediatr Scand 69: 25-30
12 Yakinci C, Pac A, Kucukaby FZ, Tayfun M, Gul A. 1997. Serum zinc, copper and magnesium levels in obese children. Acta Paediatr Jpn 39: 339-441   DOI   ScienceOn
13 Sherman AR, Guthrie HA, Woklinsky I. 1977. Interrelationships between dietary iron and tissue zinc and copper levels and serum lipids in rats. Proc Soc Exp Biol Med 156: 396-401   DOI
14 Taneja SK, Mahajan M, Arye P. 1996. Excess bioavailability of zinc may cause obesity in humans. Experientia 52: 31-33   DOI   ScienceOn
15 Failla ML, Kennedy ML, Chen ML. 1988. Iron metabolism in genetically obese (ob/ob) mice. J Nutr 118: 46-51   DOI
16 Sherman AR, Tissue NT. 1981. Tissue iron, copper and zinc levels in offspring of iron-sufficient and iron-deficient rats. J Nutr 111: 266-275   DOI
17 Jun YS. 1998. Effect of iron intakes on macromineral utilization in rats. J Korean Soc Food Sci Nutr 27: 1273-1278   과학기술학회마을
18 Jun YS, Choi MK, Kim AJ, Kim MH, Sung CJ. 2002. Effect of iron supplementation on mineral utilization in rats. J Korean Soc Food Sci Nutr 31: 1658-1663   과학기술학회마을   DOI   ScienceOn
19 Choi MK, Jun YS. 1999. Effect of copper supplementation on mineral utilization in rats. J Korean Soc Food Sci Nutr 28: 1124-1130   과학기술학회마을
20 Fisher PW, Giroux A, L'Abbe MR. 1981. The effect of diet ary zinc on intestinal copper absorption. Am J Clin Nutr 34: 1670-1675   DOI
21 Begin-Heick N, Dalpe-Scott M, Rowe J, Heick HM. 1985. Zinc supplementation attenuates insulin secretory activity in pancreatic islets of the ob/ob mouse. Diabetes 34: 179-184   DOI   ScienceOn
22 Boquist L, Lernmak A. 1989. Effect of the endocrine pancreas in Chinese hamsters fed zinc deficient diet. Acta Path Microbiol Scand 76: 215-228
23 Prasad AS. 1993. Biochemistry of zinc. Plenum Publishing, New York, USA. p 193-218
24 Kang HK, Harvey PW, Valentine JL, Swendseid ME. 1977. Zinc, iron, copper and magnesium concentrations in tissues of rats fed various amounts of zinc. Clin Chem 23: 1834-1837
25 O'Dell BL. 1989. Mineral interactions relevant to nutrient requirement. J Nutr 119: 1832-1838   DOI
26 Song MK. 1987. Influence of dietary zinc on sodium and potassium metabolism in the rat. Miner Electrolyte Metab 13: 178-182