Isolation and Purification of Decursin and Decursinol Angelate in Angelica gigas Nakai
![]() ![]() |
Kim, Kang-Min
(Dept. of Smart Foods and Drugs, Inje University)
Jung, Jae-Yeon (Dept. of Smart Foods and Drugs, Inje University) Hwang, Sung-Woo (Dept. of Smart Foods and Drugs, Inje University) Kim, Myo-Jeong (Dept. of Smart Foods and Drugs, Inje University) Kang, Jae-Seon (Dept. of Pharmacy, Kyungsung University) |
1 | Ahn MJ, Lee MK, Kim YC, Sung SH. 2008. The simultaneous determination of coumarins in Angelica gigas root by high performance liquid chromatography-diode array detector coupled with electrospray ionization/mass spectrometry. J Pharmaceut Biomed 46: 258-266 DOI ScienceOn |
2 | Yook CS. 1990. Coloured medicinal plants of Korea. Academy Book Co., Seoul. p 390 |
3 | Kang SY, Lee KY, Sung SH, Park MJ, Kim YC. 2001. Coumarins isolated from Angelica gigas inhibit acetylcholinesterase structure-activity relationships. J Nat Prod 64: 683-685 DOI ScienceOn |
4 | Lee JH, Choi YS, Kim JH, Jeong HG, Kim DH, Yun MY, Kim JS, Lee SH, Cho SH, Shen GN, Kim EG, Jin WY, Song GY. 2006. A mass preparation method of (+)-decursinol from the roots of Angelica gigas. Yakhakhoeji 50: 172-176 |
5 | Bae EA, Han MJ, Kim NJ, Kim DH. 1998. Anti-Helicobacter pylori activity of herbal medicines. Biol Pharm Bull 21: 990-992 DOI ScienceOn |
6 | Lee SH, Shin DS, Kim JS, Oh KB, Kang SS. 2003. Antibacterial courmins from Angelica gigas roots. Arch Pharm Res 26: 449-452 DOI ScienceOn |
7 | Yim DS, Singh RP, Agarwal C, Lee SY, Chi HJ. 2005. A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells. Cancer Res 65: 1035-1044 |
8 | Ahn KS, Sim WS, Kim IH. 1996. Decursin: a cytotoxic agent and protein kinase C activator from the root of Angelica gigas. Planta Med 62: 7-9 DOI ScienceOn |
9 | Ryu KS, Yook CS. 1967. Studies on the coumarins of the root of Angelica gigas Nakai. Yakhakhoeji 11: 22-26 |
10 | Kim HH, Ahn KS, Han H, Choung SY, Choi SY, Kim IH. 2005. Decursin and PDBu: two PKC activators distinctively acting in the megakaryocytic differentiation of K562 human erythroleukemia cells. Leuk Res 29: 1407-1413 DOI ScienceOn |
11 | Yim D, Singh RP, Agarwal C, Lee S, Chi H, Agarwal R. 2005. A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells. Cancer Res 65: 1035-1044 |
12 | Park KW, Choi SR, Shon MY, Jeong IY, Kang KS, Lee ST, Shim KH, Seo KI. 2007. Cytotoxic effects of decursin from Angelica gigas Nakai in human cancer cells. J Korean Soc Food Sci Nutr 36: 1385-1390 과학기술학회마을 DOI ScienceOn |
13 | Lim JD, Kim IH, Kim HH, Ahn KS, Han HG. 2001. Enantioselective synthesis of decursinol angelate and decursin. Tetrahedron Lett 42: 4001-4003 DOI ScienceOn |
14 | Lee SH, Lee YS, Jung SH, Shin KH, Kim BK, Kang SS. 2003. Anti-tumor activities of decursinol angelate and decursin from Angelica gigas. Arch Pharm Res 26: 727-730 DOI ScienceOn |
![]() |