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http://dx.doi.org/10.3746/jkfn.2009.38.12.1779

Monitoring of Ergosterol Biosynthesis Inhibitor (EBI) Pesticide Residues in Commercial Agricultural Products and Risk Assessment  

Lee, Hee-Jung (Test & Analatical Laboratory, Busan Regional Food & Drug Administration)
Choe, Won-Jo (Test & Analatical Laboratory, Busan Regional Food & Drug Administration)
Lee, Ju-Young (Test & Analatical Laboratory, Busan Regional Food & Drug Administration)
Cho, Dae-Hyun (Test & Analatical Laboratory, Gyeongin Regional Food & Drug Administration)
Kang, Chan-Soon (Test & Analatical Laboratory, Busan Regional Food & Drug Administration)
Kim, Woo-Seong (Test & Analatical Laboratory, Busan Regional Food & Drug Administration)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.38, no.12, 2009 , pp. 1779-1784 More about this Journal
Abstract
Establishment of simultaneous analysis method and monitoring for individually analyzing residual eight ergosterol biosynthesis inhibitors, EBI (difenoconazole, diniconazole, fenarimol, fenbuconazole, hexaconazole, myclobutanil, nuarimol and paclobutrazol) pesticides in commercial agricultural products, were conducted. The simultaneous analysis method for the pesticides was established using a GC/MS/MS for EBI pesticides. Residual amount of those pesticides were investigated in 989 commercial agricultural products (fifteen kinds of cereal grains, vegetables, beans, nuts, fruits and mushrooms) from seven metropolitan cities and eight provinces. In EBI pesticides analysis, linearity of GC/MS/MS analysis was 0.9974-0.9992, and that of recoveries were 86-135% with relative standard deviations (RSD) <20%. The limit of quantification (LOQ) of the method ranged from 0.5 to 5.0 mg/kg for eight EBI pesticides. According to the monitoring of the EBI pesticides in commercial agricultural products, difenoconazole, fenarimol, hexaconazole showed various residual levels (total frequency of 8/989 detection, 0.8%). Paclobutrazole showed in excess levels of the MRLs (maximum residue limits) for pesticides in one chard sample by the Korea Food Code. As a result of exposure assessment on the detected 8 individual pesticides, all pesticides (difenoconazole, fenarimol, hexaconazole, paclobutrazole) were evaluated as safe level in comparison to toxicologically acceptable daily intake.
Keywords
EBI (ergosterol biosynthesis inhibitor) pesticides; pesticide residue; exposure assessment;
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1 Kishorekumar A, Abdul Jaleel C, Manivannan P, Sankar B, Sridharan R, Murali PV, Panneerselvam R. 2007. Comparative effects of different triazole compounds on growth, photosynthetic pigments and carbohydrates metabolism of Solenostemon rotundifolius. Colloids Surf B Biointerfaces 60: 207-212   DOI   ScienceOn
2 Nguyen TD, Han EM, Seo MS, Kim SR, Yun MY, Lee DM, Lee GH. 2008. A multi-residue method for the determination of 203 pesticides in rice paddies using gas chromatography/mass spectrometry. Analytica Chimica Acta 619: 67-74   DOI   ScienceOn
3 Park HR, Kim SS, Ham HJ, Park DS, Hur JH. 2006. Residual analysis and establishment of standard for safe use of myclobutanil in the pear. Inst Agr Sci Kangwon Nat'l Univ J Agric Sci 17: 95-100
4 Manclus JJ, Moreno MJ, Plana E, Montana A. 2008. Development of monoclonal immunoassays for the determination of triazole fungicides in fruit juices. J Agric Food Chem 56: 8793-8800   DOI   ScienceOn
5 Tomlin C. 2007. The Pesticide Manual. 14th ed. Britsh Crop Protection Council, Surrey, UK
6 Wolf DC, Allen JW, George MH, Hester SD, Sun G, Moore T, Thai SF, Delkor D, Winkfield E, Leavitt S, Nelson G, Roop BC, Jones C, Thibodeaux J, Nesnow S. 2006. Toxicity profiles in rats treated with tumorigenic and nontumorigenic triazole conazole fungicides: propiconazole, triadimefon and myclobutanil. Toxicol Pathol 34: 895-902   DOI   ScienceOn
7 Kishorekumar A, Abdul Jaleel C, Manivannan P, Sankar B, Sridharan R, Murali PV, Panneerselvam R. 2008. Comparative effects of different triazole compounds on antioxidant metabolism of Solenostemon rotundifolius. Colloids Surf B Biointerfaces 62: 307-311   DOI   ScienceOn
8 Manivannan P, Abdul Jaleel C, Kishorekumar A, Sankar B, Somasundaram R, Panneerselvam R. 2008. Protection of Vigna unguiculata (L.) Walp. plants from salt stress by paclobutrazol. Colloids Surf B Biointerfaces 61: 315-318   DOI   ScienceOn
9 Kyung KS, Lee BM, Lee JK. 2004a. Behavior of the soil residues of the fungicide hexaconazole in a rice plants- grown microsystem (pot). Kor J Pesticide Sci 8: 198-209   과학기술학회마을
10 Kyung KS, Lee BM, Ihm YB, Lee YD, Han SS, Choi JH, Kim JH, Ryu GH, Lee JK. 2004b. Adsorption and leaching characteristics of fungicide hexaconazole. Kor J Pesticide Sci 8: 46-53   과학기술학회마을
11 Han SS, Kim IK. 1996. Gas chromatographic analysis on residual difenoconazole in apple and soil. Anal Sci Technol 9: 123-133
12 Oliva J, Barba A, Vela N, Melendreras F, Navarro S. 2000. Multiresidue method for the rapid determination of organophosphorus insecticides in grapes, must and wine. J Chromatogr A 882: 213-220   DOI   ScienceOn
13 Correia M, Delerue-Matos C, Alves A. 2001. Development of a SPME-GC-ECD methodology for selected pesticides in must and wine samples. Fresenius J Anal Chem 369: 647-651   DOI
14 KFDA. 2008. Korea Food Code. Korean Food and Drug Administration. Seoul, Korea. No. 71 p 10-9-71-1-10-9-72-1
15 Nguyen TD, Lee BS, Lee BR, Lee DM, Lee GH. 2007. A multiresidue method for the 5 determination of 109 pesticides in rice using the Quick Easy Cheap Effective Rugged and Safe (QuEChERS) sample preparation method and gas chromatography/mass spectrometry with temperature control and vacuum concentration. Rapid Commun Mass Spectrom 21: 3115-3122   DOI   ScienceOn