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http://dx.doi.org/10.3746/jkfn.2009.38.12.1707

Effects of the Ethanol Extract from Lycii folium Leaves on Obesity and Blood Biochemical Indices in High-fat Diet Induced Obese Rats  

Choi, Mi-Kyeong (Dept. of Food and Nutrition, Kongju National University)
Lee, Jae-Soon (Dept. of Food Science and Nutrition, Hoseo University)
Park, Won-Jong (Dept. of Food Science and Technology, Kongju National University)
Kim, Mi-Hyun (Dept. of Food and Nutrition, Kangwon National University)
Kang, Myung-Hwa (Dept. of Food Science and Nutrition, Hoseo University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.38, no.12, 2009 , pp. 1707-1711 More about this Journal
Abstract
This study was conducted to investigate the effects of ethanol extract from Lycii folium (L. folium) leaves on obesity index, serum lipids, homocysteine, leptin, ghrelin, and glucose in obese rats. Sprague-Dawley rats were administrated high-fat diets to induce obesity. Then, obese rats were divided into three diet groups: a basal-diet obese group (BO group), high-fat diet obese group (FO group), and high-fat diet plus L. folium extract obese group (FLEO group). Three groups were each fed experimental diet for 8 weeks. There were no significant differences in body weight and FER among the groups. However, obesity index such as Ro？hrer index, Lee index, and T.M. index of FLEO group was significantly decreased as compared to FO group. While serum triglyceride of BO group was significantly decreased as compared to FO group, there were no significant differences in serum lipids, homocysteine, leptin, ghrelin and glucose between FLEO group and FO group. In conclusion, these results indicated that ethanol extract from L. folium leaves might be beneficial with anti-obese effect by reduction of obesity indices in obese rats.
Keywords
Lycii folium; lipids; homocysteine; leptin; ghrelin; obese; rats;
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Times Cited By KSCI : 6  (Citation Analysis)
Times Cited By SCOPUS : 1
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