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http://dx.doi.org/10.3746/jkfn.2008.37.8.1044

The Stabilization of Lactic Acid Bacteria, Bacillus polyfermenticus KJS-2  

Kim, Kang-Min (Dept. of Pharmaceutical Engineering, Inje University)
Lee, Jin-Young (Dept. of Pharmaceutical Engineering, Inje University)
Hong, Yong-Geun (Dept. of Physical Therapy, Inje University)
Lee, Sang-Kil (Dept. of Pharmaceutical Engineering, Inje University)
Kang, Jae-Seon (Dept. of Pharmaceutical Engineering, Inje University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.37, no.8, 2008 , pp. 1044-1048 More about this Journal
Abstract
Bacillus polyfermenticus KJS-2 (Bp2) was isolated from $Bispan^{(R)}$, a commercially available probiotics consisting of more than 4 strains. The objective of this study was to investigate the effect of three-layer coating on the stabilty of Bp2. Bp2 was microencapsulated with sodium alginate using an air atomizer. The Bp2 loaded pellets were also coated with HFP-chitosan and HPMCP for oral delivery system. When compared to the uncoated Bp2, the survival of the three-layer coated Bp2 increased to approximately 63% (p<0.01) in a 30% ethanol solution, 54% (p<0.05) in an artificial gastric juice (pH 2), and 53% (p<0.05) in the bile acid (pH 5). When coated beads were stored at $100^{\circ}C$ and $130^{\circ}C$, Bp2 in coated beads was very stable (p<0.01) compared to uncoated Bp2.
Keywords
Bacillus polyfermenticus KJS-2; three-layer coating; alginate; stability;
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Times Cited By KSCI : 4  (Citation Analysis)
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