1 |
Yeh KY, Yeh M, Glass J. 2004. Hepcidin regulation of ferroportin 1 expression in the liver and intestine of the rat. Am J Physiol Gastrointest Liver Physiol 286: 385-394
DOI
ScienceOn
|
2 |
Dallalio G, Fleury T, Means RT. 2003. Serum hepcidin in clinical specimens. Br J Haematol 122: 996-1000
DOI
ScienceOn
|
3 |
Chaston T, Chung B, Mascarenhas M, Marks J, Patel B, Srai SK, Sharp P. 2008. Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells. Gut 57: 374-382
DOI
ScienceOn
|
4 |
Park CH, Valore EV, Waring AJ, Ganz T. 2001. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 276: 7806-7810
DOI
ScienceOn
|
5 |
Nicolas G, Bennoun M, Porteu A, Mativet S, Beaumont C, Grandchamp B, Sirito M, Sawadogo M, Kahn A, Vaulont S. 2002. Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci U S A 99: 4596-4601
DOI
ScienceOn
|
6 |
Pigeon C, Ilyin G, Courselaud B, Leroyer P, Turlin B, Brissot P, Loreal O. 2001. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 276: 7811-7819
DOI
ScienceOn
|
7 |
Frazer DM, Wilkins SJ, Becker EM, Vulpe CD, McKie AT, Trinder D, Anderson GJ. 2002. Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats. Gastroenterology 123: 835-844
DOI
ScienceOn
|
8 |
Jumarie C, Malo C. 1991. Caco-2 cells cultured in serum- free medium as a model for the study of enterocytic differentiation in vitro. J Cell Physiol 149: 24-33
DOI
|
9 |
Yamaji S, Sharp P, Ramesh B, Srai SK. 2004. Inhibition of iron transport across human intestinal epithelial cells by hepcidin. Blood 104: 2178-2180
DOI
ScienceOn
|
10 |
Chua AC, Graham RM, Trinder D, Olynyk JK. 2007. The regulation of cellular iron metabolism. Crit Rev Clin Lab Sci 44: 413-459
DOI
ScienceOn
|
11 |
Papanikolaou G, Pantopoulos K. 2005. Iron metabolism and toxicity. Toxicol Appl Pharmacol 202: 199-211
DOI
ScienceOn
|
12 |
Weinberg ED. 2008. Iron out-of-balance: A risk factor for acute and chronic diseases. Hemoglobin 32: 117-122
DOI
ScienceOn
|
13 |
Roy CN, Enns CA. 2000. Iron homeostasis: new tales from the crypt. Blood 96: 4020-4027
|
14 |
Montosi G, Donovan A, Totaro A, Garuti C, Pignatti E, Cassanelli S, Trenor CC, Gasparini P, Andrews NC, Pietrangelo A. 2001. Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J Clin Invest 108: 619-623
DOI
|
15 |
Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J. 2004. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306: 2090-2093
DOI
ScienceOn
|
16 |
Ganz T. 2005. Hepcidin: a regulator of intestinal iron absorption and iron recycling by macrophages. Best Pract Res Clin Haematol 18: 171-182
DOI
ScienceOn
|
17 |
Abboud S, Haile DJ. 2000. A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem 275: 19906-19912
DOI
ScienceOn
|
18 |
Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, Kingsley PD, Palis J, Fleming MD, Andrews NC, Zon LI. 2000. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 403: 776-781
DOI
ScienceOn
|
19 |
McKie AT, Marciani P, Rolfs A, Brennan K, Wehr K, Barrow D, Miret S, Bomford A, Peters TJ, Farzaneh F, Hediger MA, Hentze MW, Simpson RJ. 2000. A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell 5: 299-309
DOI
ScienceOn
|
20 |
Ganz T. 2004. Hepcidin in iron metabolism. Curr Opin Hematol 11: 251-254
DOI
ScienceOn
|
21 |
Nicolas G, Bennoun M, Devaux I, Beaumont C, Grandchamp B, Kahn A, Vaulont S. 2001. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci U S A 98: 8780-8785
DOI
ScienceOn
|
22 |
Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T. 2004. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 113: 1271-1276
DOI
|
23 |
Nemeth E, Ganz T. 2006. Regulation of iron metabolism by hepcidin. Annu Rev Nutr 26: 323-342
DOI
ScienceOn
|
24 |
Knutson MD, Vafa MR, Haile DJ, Wessling-Resnick M. 2003. Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages. Blood 102: 4191-4197
DOI
ScienceOn
|
25 |
Fleming MD, Romano MA, Su MA, Garrick LM, Garrick MD, Andrews NC. 1998. Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci U S A 95: 1148-1153
DOI
|
26 |
Njajou OT, Vaessen N, Joosse M, Berghuis B, van Dongen JW, Breuning MH, Snijders PJ, Rutten WP, Sandkuijl LA, Oostra BA, van Duijn CM, Heutink P. 2001. A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis. Nat Genet 28: 213-214
DOI
ScienceOn
|
27 |
Devalia V, Carter K, Walker AP, Perkins SJ, Worwood M, May A, Dooley JS. 2002. Autosomal dominant reticuloendothelial iron overload associated with a 3-base pair deletion in the ferroportin 1 gene (SLC11A3). Blood 100: 695-697
DOI
ScienceOn
|
28 |
Roetto A, Totaro A, Piperno A, Piga A, Longo F, Garozzo G, Cali A, De Gobbi M, Gasparini P, Camaschella C. 2001. New mutations inactivating transferrin receptor 2 in hemochromatosis type 3. Blood 97: 2555-2560
DOI
ScienceOn
|