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http://dx.doi.org/10.3746/jkfn.2007.36.9.1134

Effects of Camellia sinensis Extracts on the Antioxidant System and Alcohol Down-Regulation Enzymes in Sub-Acute Ethanol Treated ICR Mice  

Koo, Sung-Ja (Dept. of Food & Nutrition, Kyunghee University)
Choi, Il-Sook (Dept. of Food & Nutrition, Kyunghee University)
Kong, Yeon-Hee (Korea Food Research Institute)
Choi, Sang-Yoon (Korea Food Research Institute)
Jo, Youn-Ock (Dept. of Food & Nutrition, Kyunghee University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.36, no.9, 2007 , pp. 1134-1139 More about this Journal
Abstract
This study was conducted to investigate the effects of four kinds of tea (Camellia sinensis) extracts on the antioxidant defense systems as well as the activities of alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) in ethanol administered ICR mice. According to the results, treatment with puerh tea significantly increased the superoxide dismutase activity and glutathion reductase activity in liver. In addition, the group treated with oolong tea exhibited higher superoxide dismutase activity and glutathion reductase activity in serum than those of puerh tea, green tea and black tea treated groups. The oolong tea and puerh tea also reduced malondealdehyde contents in both liver and serum. These results suggested that puerh tea and oolong tea were the most effective against alcohol-induced oxidative damage among the Camellia sinensis teas. On the other hand, in the measurement of alcohol break-down enzyme activities, the group treated with green tea exhibited the highest hepatic ADH and ALDH activities, suggesting that the group treated with green tea might be useful for alcohol down-regulation.
Keywords
Camellia sinensis; antioxidant; ADH; ALDH;
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