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http://dx.doi.org/10.3746/jkfn.2007.36.7.926

Detection of Diarrhetic Shellfish Poisons by LC-MS/MS  

Yun, So-Mi (Division of Marine Life Science and Technology, Institute of Marine Industry, Gyeongsang National University)
Jang, Jun-Ho (Graduate School of Agricultural Science, Tohoku University)
Shin, Il-Shik (Faculty of Marine Bioscience & Technology, Kangnung National University)
Lee, Jong-Ok (Food Contaminants Team, Korea Food and Drug Administration)
Lee, Jong-Soo (Division of Marine Life Science and Technology, Institute of Marine Industry, Gyeongsang National University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.36, no.7, 2007 , pp. 926-931 More about this Journal
Abstract
Diarrhetic shellfish poisons (DSP) such as okadaic acid (OA), dinophysistoxin-1 (DTX1), pectenotoxin-1(PTX1), PTX2, PTX6 and yessotoxin (YTX) were determined simultaneously by LC-MS/MS and mouse bioassay in the shellfishes (oyster, mussel, Washington purple clam, ark shell, scallop and short necked clam) collected at Tongyeong, from March to September, 2006. Oyster and mussel were found to contain DSP (0.05${\sim}$0.1 MU/g) in March by mouse bioassay; however, no DSP components were detected on the LC-MS/MS. Also, a small amount of DTX1 (0.05 ${\mu}g/g$) in mussel (June) and OA (0.01${\sim}$0.02 ${\mu}g/g$) in 5 species of shellfishes(August) were determined by LC-MS/MS.
Keywords
diarrhetic shellfish poison (DSP); LC-MS/MS; mouse bioassay; shellfish; okadaic acid (OA); dinophysistoxin-1 (DTX1);
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