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http://dx.doi.org/10.3746/jkfn.2006.35.10.1356

Effect of Enzymatic Hydrolysate of Hamcho (Salicomia herbacea) on Antioxidative Defense System in Rats Fed High Cholesterol Diet  

Kim, Kyung-Ran (Dept. of Food Science and Nutrition, Catholic University of Daegu)
Choi, Jeong-Hwa (School of Food Science, Jinju International University)
Lee, Sung-Kwon (Dept. of Food Science and Nutrition, Catholic University of Daegu)
Woo, Mi-Hee (College of Pharmacy, Catholic University of Daegu)
Choi, Sang-Won (Dept. of Food Science and Nutrition, Catholic University of Daegu)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.35, no.10, 2006 , pp. 1356-1362 More about this Journal
Abstract
The purpose of the present study was to investigate the effect of enzymatic hydrolysate (extract) of Salicomia herbacea L. (Korean name: Hamcho) on antioxidative defense system in rats fed high cholesterol diet. Rats were divided into six experimental groups which are composed of normal diet group, normal diet group supplemented with 2% Hamcho extract, high cholesterol diet group, high cholesterol diet groups supplemented with 1%, 2% and 4% Hamcho extracts. The activity of serum glutamate oxaloacetae transaminase in rats was not different among all experimental groups, while the activity of glutamate pyruvate transaminase in groups supplemented with Hamcho extract was significantly lower than that of high cholesterol control group. Supplementation of Hamcho extract (SHE) to the high cholesterol fed rats resulted in increased activities of hepatic superoxide dismutase and glutathione peioxidase. However, there was no significant difference in the activity of hepatic catalase among all experimental groups. SHE also resulted in decreased levels of hepatic thiobarbituric acid reactive substances and mitochondrial carbonyl values. Those effects were higher to some extent in 2% and 4% Hamcho extract groups than those of high cholesterol control group. These results suggest that enzymatic hydrolysate of Hamcho may reduce oxidative damage by activation of antioxidative defense system in rats fed high cholesterol diets.
Keywords
Hamcho (Salicornia herbacea L.); enzymatic hydrolysates; high cholesterol diet; antioxidative defense system;
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