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http://dx.doi.org/10.3746/jkfn.2005.34.6.821

Hypoglycemic Effect of Paecilomyces japonica in NIDDM Patients  

Kim, Hyun-Sook (Institute of Korea Nutritional Science, Kangwon National University)
Choe, Myeon (Dept. of Animal Food Science, Kangwon National University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.34, no.6, 2005 , pp. 821-824 More about this Journal
Abstract
The purpose of this study is to investigate tile effects of the Paecilomyces japonica on blood glucose in non-insulin dependent diabetes mellitus volunteers. During the 3 months of the experimental period, freeze-dried powder of Paecilomyces japonica (2 g/meal) was given to the subjects right before each meal. Paecilomyces japonica caused a significant decrease of $27.5\%\;and\;35.5\%$ in fasting and postprandial blood glucose levels, respectively. There were significant reductions of $28.5\%\;and\;33.5\%$ in fasting and postprandial blood glucose levels of the male subjects, respectively Paecilomyces japonica also significantly decreased in fasting and postprandial blood glucose levels of $26.1\%\;and\;37.3\%$ in female patients after treatment. This study shows that Paecilomyces japonica supplementation significantly lowered the fasting and postprandial glucose levels in NIDDM patients. These effects presumably contribute to the hypoglycemic activity.
Keywords
Paecilomyces japonica; diabetes mellitus; hypoglycemic; blood glucose;
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