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http://dx.doi.org/10.3746/jkfn.2005.34.5.638

Effect of Dietary Iron and Exercise on Heme Biosynthesis and Lipid Metabolism of Rats  

Choi, Jee-Young (Dept. of Food and Nutrition, Yongin University)
Kim, Hye-Young P. (Dept. of Food and Nutrition, Yongin University)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.34, no.5, 2005 , pp. 638-643 More about this Journal
Abstract
This study was peformed to investigate the effect of dietary iron and exercise on heme biosynthesis and lipid metabolism of rats. Rats were divided into 4 groups according to dietary iron supplement (Fe-,5 ppm vs. Fe+, 50 ppm) and exercise status (control us exercise). The experiment continued for 8 weeks. Regular treadmill exercise ($6^{\circ}$, 28 m/min, 30 min duration, 5 days/week) was given to exercise groups. The aminolevulinate dehydrase activity of red blood cell, the marker of heme biosynthesis, was significantly increased in the exercise group. Regular aerobic exercise reduced body weight and epidydimal fat pad gain. Regular exercise also significantly decreased the plasma triglyceride, cholesterol and HDL-cholesterol of the rats. Meanwhile, the iron deficiency decreased the hematocrit and hemoglobin concentration and increased the accumulation of liver cholesterol.
Keywords
iron; exercise; heme biosynthesis; triglyceride; cholesterol; rats;
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