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http://dx.doi.org/10.3746/jkfn.2005.34.1.008

Inhibitory Effects on Cell Survival and Quinone Reductase Induced Activity of Aster yomena Fractions on Human Cancer Cells  

Jung, Bok-Mi (여수대학교 식품영양학과)
Lim, Sing-Sn (여수대학교 식품영양학과)
Park, Yun-Ja (신라대학교 식품영양학과)
Bae, Song-Ja (신라대학교 식품영양학과)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.34, no.1, 2005 , pp. 8-12 More about this Journal
Abstract
This study was performed to determine the inhibitory effects on cell survival and Quinone reductase induced activity of Aster yomena (AY) on human cancer cells which, using methanol, was extracted and fractionated into five different solvent types: hexane (AYMH), ethylether (AYMEE), ethylacetate (AYMEA), butanol (AYMB) and aqueous (AYMA) partition layers. The experiment was conducted to determine cytotoxicity of various Aster yomena partition layers on HepG2, HeLa and MCF-7 cells by MTT assay. Among various partition layers of Aster yomena, A YMEE and A YMEA showed the strong cytotoxic effects on all cancer cell lines we used. The Quinone reductase (QR) induced activity on HepG2 cells, A YMH at a does of 100 $\mu$g/mL was 2.46 times more effective compared to the control value of 1.0.
Keywords
Aster yomena; cytotoxicity; quinone reductase; human cancer cell lines;
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Times Cited By KSCI : 1  (Citation Analysis)
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