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http://dx.doi.org/10.3746/jkfn.2005.34.10.1525

Anti-tumor Activity of Fermented Liquid Opuntia humifusa in Cervical Cancer Cells and Its Chemical Composition  

Choi, Hwa-Jung (Dept. of Interdisciplinary Program in Agricultural Biotechnology, Seoul National University)
Park, Seung-Chun (College of Vererinary Medicine, Kyungpook National University)
Hong, Tae-Hee (Dept. of Food Nutrition & Daejeon Health Sciences College)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.34, no.10, 2005 , pp. 1525-1530 More about this Journal
Abstract
The purpose of this study is to investigate anti-tumor activities, general composition, elemental composition and mineral contents of fermented liquid stem, root and fruit of Opuntia humifusa. In the general composition, the energy, crude protein, crude lipid and crude carbohydrate contents of fermented liquid stem were 86.21 Kcal, 0.92$\%$, 0.12$\%$, and 20.34$\%$, respectively. Fermented liquid fruit showed 65.32 Kcal, 1.04$\%$, 0.08$\%$, and 15.15$\%$. In mineral analysis, fermented liquid stem and fruit showed 1,800 and 388 mg of calcium per 100g. The ferrous concentrations of fermented liquid stem and fruit were 21 and 10 mg per 100 g, respectively. Methanol, ethanol and water extracts of nonfermented liquid stem and fruit did not inhibit the proliferation in human cervical cancer cells (Caski, SiHa and HaCaT), but the fermented liquid fruit showed the inhibition of Proliferation with dose-response manner in Caski and SiHa cells, but not HaCaT. Therefore, it suggests that fermented cactus may be used as one of potential adjuvant for the treatment of cervical carcinomas.
Keywords
Opuntia humifusa; chemical composition; anti-tumor activity; fermented cactus fruit; adjuvant;
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