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http://dx.doi.org/10.3746/jkfn.2004.33.5.810

Evaluation of Safety for the Supplement of Herbicide-resistant Rice in Old Male Rats  

이성현 (농업과학기술원 농촌자원개발연구소 농산물가공이용과)
박홍주 (농업과학기술원 농촌자원개발연구소 농산물가공이용)
조소영 (농업과학기술원 농촌자원개발연구소 농산물이용)
전혜경 (농업과학기술원 농촌자원개발연구소 농산물가공이용)
박용환 (농업생명공학연구원 유전자제어공학과)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.33, no.5, 2004 , pp. 810-814 More about this Journal
Abstract
This research was conducted to evaluate the safety of the herbicide-resistant rice, a genetically modified organism (GMO) developed by the Rural Development Administration by exposing it to 12 months old Sprague-Dawley rats for 8 weeks. The composition of herbicide-resistant brown rice with/without heating treatment was compared with those of conventional Ilpum brown rice with/without heating treatment to assess composition equivalence. Compositional analysis was performed to measure proximates, fiber, and minerals. The nutritional components of herbicide-resistant rice were similar to those of the nontransgenic control or were within the normal range of nontransgenic rice. Four groups of experimental male rats were fed one of the following diets for eight weeks: Ilpum brown rice (I) and its heated rice (IH) as non-GMO, and herbicide-resistant brown rice (G) and its heated rice (GH) as GMO- We checked clinical symptoms (anorexia, salivation, diarrhea, polyuria, anuria, fecal change), food intake, and water consumption every day, change of body weight once a week, and serum biochemistry and organ weights after 8 weeks of experimental feeding We did not find any significant differences in the above-mentioned items. These results suggested that genetically modified herbicide-resistant rice was compositionally equivalent to conventional Ilpum rice, and nutritional characteristics and safety of herbicide-resistant rice in old male rats treated for 8 weeks were not different from those of Ilpum rice, non-GMO.
Keywords
herbicide-resistance rice; GMO; nutrients; safety; old male rats;
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