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http://dx.doi.org/10.3746/jkfn.2004.33.1.182

Genotoxicological Safety of Gamma-Irradiated Kwamegi(semi-dried Colobabis seira)  

육홍선 (충남대학교 식품영양학과)
정영진 (충남대학교 식품영양학과)
송현파 (한국원자력연구소 방사선식품ㆍ생명공학연구팀)
이주운 (한국원자력연구소 방사선식품ㆍ생명공학연구팀)
변명우 (한국원자력연구소 방사선식품ㆍ생명공학연구팀)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.33, no.1, 2004 , pp. 182-192 More about this Journal
Abstract
Gamma irradiation at 5 and 10 kGy was applied to Kwamegi (semi-dried Colobabis seira) for their possible hygiene quality and carried out genotoxicological safety. In vitro genotoxicological safety of each 5 and 10 kGy-irradiated Kwamegi was evaluated by Salmonella typhimurium (TA98, TA100, TA1535 and TA1537) and E. coli WP2 uvrA reversion assay, SOS chromotest (Escherichia coli PQ37) and chromosome aberration test (Chinese hamster lung fibroblast cells) in the absence and presence of an exogenous metabolizing system (S9 mix). Gamma-irradiated samples were not different from nonirradiated-control to respective in vitro tests. And in vivo micronucleus test using ICR mice (male) micronucleus was not observed. Kwamegi exposed to 10 kGy-gamma ray revealed negative results in these three in vitro mutagenetic tests and in vivo micronucleus test up to 10,000 $\mu\textrm{g}$/plate, respectively. The results indicated that 5 and 10 kGy gamma-irradiated Kwamegi (semi-dried Colobabis seira) did not have mutagenicity.
Keywords
Kwamegi (semi-dried Colobabis seira); gamma irradiation; Ames test; SOS chromotest; chromosome aberration test; micronucleus test;
Citations & Related Records
Times Cited By KSCI : 5  (Citation Analysis)
연도 인용수 순위
1 Studies on the genotoxicity of the gamma-irradiated Panax Ginseng Radix in vitro and in vivo /
[ Ha,K.W.;Jung,H.K.;Oh,H.Y.;Heo,O.S.;Sohn,S.J.;Han,E.S.;Jung,S.C.;Choi,B.Y.;Kim,Y.M.;Kim,P.S.;Moon,H.H. ] / J Food Hyg Safety   과학기술학회마을
2 Quality properties of gamma irradiated Kwamegi (semidried Cololabis seira) /
[ Kim,D.J.;Lee,J.W.;Cho,K.H.;Yook,H.S.;Byun,M.W. ] / Korean J Food Sci Technol
3 The present status of nutrition-related diseases and its countermeasures /
[ Huh,K.B. ] / Korean J Nutrition   과학기술학회마을
4 Review of the safety and nutritional adequacy of irradiated food /
[ World Health Organization ] / WHO/HPP/FOS/92.2
5 Effect of Pacific saury (Cololabis saira) on serum cholesterol and component fatty acid in humans /
[ Uhei,N.;Sumiko,K.;Kunitoshi,S. ] / Eiyogaku Zasshi   DOI
6 Genotoxicological and acute toxicological safeties of gamma irradiated beef /
[ Kang,I.J.;Kwak,H.J.;Lee,B.H.;Kim,K.H.;Byun,M.W.;Yook,H.S. ] / J Korean Soc Food Sci Nutr
7 Wholesomeness of irradiated food /
[ WHO ] / Report of a Joint FAO/IAEA?WHO Expert Committee.Tech. Rep.651
8 The bone marrow micronucleus test /
[ Heddle,J.A.;Stuart,E.;Salamone,M.F.;Kilbey,B.J.(ed.);Legator,M.(ed.);Nichols,W.(ed.);Ramel,C.(ed.) ] / Handbook of mutagenicity test procedures(2nd ed.)
9 The SOS Chromotest, a colorimetric bacterial assay for genotoxins: procedures /
[ Quillardet,P.;Hofnung,M. ] / Mutation Res   DOI   ScienceOn
10 의약품안전성시험관리기준 /
[ 식품의약품안전청 ] / 고시 제 1998-17호
11 In vitro genotoxicological safety of fresh vegetable-extract juice by gamma irradiation /
[ Lee,H.J.;Kang,K.W.;Yook,H.S. ] / J Korean Soc Food Sci Nutr   과학기술학회마을
12 화학물질 유해성시험연구기관의 지정 등에 관한 규정 /
[ 국립환경연구원 ] / 고시 제 1998-41호
13 Revised methods for the Salmonella mutagenicity test /
[ Maron,D.M.;Ames,B.N. ] / Mutat Res   DOI
14 Genotoxicological safety on water-soluble fraction of gamma irradiated Korean soybean fermentation foods /
[ Yook,H.S.;Lee,E.M.;Kim,D.H.;Lee,K.H.;Lee,H.J.;Lee,Y.N.;Byun,M.W. ] / J Food Hyg Safety   과학기술학회마을
15 /
[ World Health Organization ] / Global health situation and projections estimates
16 Genotoxicological safety of the gamma-irradiated Korean red ginseng In vitro /
[ Jo,S.K.;Yook,H.S.;Byun,M.W. ] / J Korean Soc Food Sci Nutr
17 /
[ ICGFI ] / Summary report, Eleventh Meeting of the International Consultative Group on Food Irradiation
18 Application of irradiation techniques to food industry /
[ Byun,M.W. ] / Radioisotope News
19 Statistical analysis on in vivo cytogenetic assays /
[ Lovell,D.P.;Anderson,D.:Albaness,R.;Amphlett,G.E.;Clare,G.;Ferguson,R.;Richold,M.;Papworth,D.G.;Savage,J.R.K.;Kirkland,D.J.(ed.) ] / Statistical evaluation of mutagenicity test data
20 Codex general standard for irradiated foods and recommended international code of practice for the operation of radiation facilities used for the treatment of foods /
[ Codex Alimentarius Commission ] / CAC/VOL.XV
21 Chromosomal aberration tests in vitro as a primary screening tool for environmental mutagens and/or carcinogens /
[ Ishidate,M.Jr.;Sofuni,T.;Yoshikawa,K. ] / GANN Monograph on Cancer Res
22 /
[ SAS Institute ] / SAS/STAT User's Guide(Version 6)(4th ed.)
23 /
[ JEMS-MMS ] / Atlas of chromosome aberration by chemicals, Japanese environmental mutagen society-mammalian mutagenicity study group
24 의약품 등의 독성시험기준 /
[ 식품의약품안전청 ] / 고시 제 1999-61호
25 Genotoxicological safety of the gamma-irradiated Korean red ginseng in vitro /
[ Jo,S.K.;Yook,H.S.;Byun,M.W. ] / J Korean Soc Food Nutr   과학기술학회마을
26 /
[ SAS Institute ] / SAS/STAT User's Guide(Version 6)(4th ed.)
27 New approaches to regulating food safety /
[ Roberts,T.;Unnevehr,L. ] / Food Rev
28 Improvement of the hygienic quality and shelf-life of Kwamegi from Cololabis seira by gamma irradiation /
[ Cho,K.H.;Lee,J.W.;Kim,J.H.;Ryu,G.H.;Yook,H.S.;Byun,M.W. ] / Korean J Food Sci Technol
29 Assays for the detection of chemically-induced chromosome damage in cultured mamalian cells /
[ Dean,B.J.;Danford,N.;Venitt,S.(ed.);Parry,J.M.(ed.) ] / Mutagenicity testing-a practical approach