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http://dx.doi.org/10.3746/jkfn.2004.33.10.1618

Effect of Small Black Soybean Powder on Blood Glucose and Insulin Sensitivity in Streptozotocin-Induced Diabetic Rats  

Lee, Dae-Hoon (원광대학교 생명과학부)
Kwak, Dong-Hoon (원광대학교 생명과학부)
Kim, Sung-Min (원광대학교 생명과학부)
Ju, Eun-Jin (원광대학교 생명과학부)
Choi, Han-Gil (원광대학교 생명과학부)
Kim, Ok-Hee (영산식품)
Hwang, Jin-Bong (한국식품연구원 분석평가팀)
Bae, Nahm-Gung (한국식품연구원 분석평가팀)
Jung, Kyu-Yong (원광대학교 의과대학 약리학교실)
Han, Jin-Chul (대구대학교 생명공학전공)
Park, Hum-Dai (대구대학교 생명공학전공)
Choo, Young-Kug (원광대학교 생명과학부)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.33, no.10, 2004 , pp. 1618-1625 More about this Journal
Abstract
Beans are acknowledged to be food resources, which have more abundant proteins and fats. The constituent parts of beans (i.e. aspartic aid, glycine, arginine) are effective against diabetes, and dietary fiber contained in the beans has an important property to maintain insulin sensitivity. Based on these, using streptozotocin (STZ)-induced diabetic rats, this study examined how the rat-eye soybean, which is principal products of the Imsil province, is effective to attenuate and/or prevent the development of diabetes mellitus. We divided rats into the non-diabetic and diabetic group, and diabetic group was further subdivided into six experimental groups [DC, diabetic control; DI, diabetes with insulin treatment (4∼6 IU/rat); DB, diabetes with black bean; DY, diabetes with yellow soybean; DS, diabetes with rat-eye soybean; DSS, diabetes with vinegar-fermented rat-eye soybean. All bean treatment (1.5 mg/l g body weight).]. Food efficiency ratio (FER), body weight and insulin sensitivity in diabetic rats were significantly reduced compared to those in normal control animals. These reductions were obviously attenuated by administration of a variety of beans used in this study (20∼30%), and the recovery effects were comparable to the results obtained by insulin treatment. Taken together, this study suggests that all beans used may have an essential property to improve and/or attenuate the development of diabetes mellitus in rats.
Keywords
small black soybean; blood glucose; insulin sensitivity;
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