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http://dx.doi.org/10.3746/jkfn.2003.32.8.1364

Effect of Seatangle Oligosaccharide Drink on Serum and Hepatic Lipids in Rats Fed a Hyperlipidemic Diet  

주동식 (동해대학교 외식산업학과)
이진경 (강릉대학교 동해안해양생물자원연구센터)
최용석 (강릉대학교 동해안해양생물자원연구센터)
조순영 (강릉대학교 동해안해양생물자원연구센터)
제외권 (동명대학 식품가공과)
최종원 (경성대학교 약학대학)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.32, no.8, 2003 , pp. 1364-1369 More about this Journal
Abstract
In this study, we investigated the effect of seatangle drink and seatangle extract product on weight gain and serum and hepatic lipid composition in rats fed a hyperlipidemic diet. In the dietary hyperlipidemia induced rats, it was observed that serum triglyceride, phospholipid, total lipid, LDL-cholesterol level and atherosclerotic index were higher, while the HDL-cholesterol level was lower when compared to the normal group. Total hepatic lipid and cholesterol content of the dietary hyperlipidemia induced rats was conspicuously decreased by seatangle drink and seatangle extract product treatment. Especially, triglyceride content was decreased to 30% by seatangle drink treatment, and 45% by seatangle extract product treatment.
Keywords
seatangle drink; seatangle extract product; dietary hyperlipidemic rat; triglyceride; total lipid;
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Times Cited By KSCI : 4  (Citation Analysis)
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1 Goldstein JL, Brown MS. 1975. Familial hypercholesterolemia. A genetic regulatory defect in cholesterol metabolism. Am J Med 58: 147-152.   DOI   ScienceOn
2 Beaumont JL, Carlson LA, Cooper GR, Frejfar Z, Fredrickson DS, Strasser T. 1970. Classification of hyperlipidemia and hyperlipoproteinemias. Bull WHO 43: 891-897.
3 Folch J, Lees M, Stanley GH. 1957. A simple method for the isolation and purification of total lipds from animal tissues. J Biol Chem 226: 497-502.
4 Joo DS, Choi YS, Cho SY. 2003. Preparation of the depolymerized alginate by physical treatment processing with organic acids. J Korean Fish Soc 36: 1-5.   과학기술학회마을
5 Nam SM, Ham SS, Oh DH, Kang IJ, Lee SY, Chung CK. 1998. Effects of Artemisia kitamura ethanol extracts on lowering serum and liver lipids in rats. J Korean Soc Food Sci Nutr 27: 338-343.   과학기술학회마을
6 Grodstein F. 1997. Postmenopausal hormone therapy and mortality. N Engl J Med 336: 1769-1774.   DOI   ScienceOn
7 McGowan MW, Artiss JD, Strandbergh DR. 1983. A peroxidase- coupled method for the colorimetricdetermination of serum triglycerides. Clin Chem 29: 538-543.
8 Choi JH, Kim DW. 1997. Effect of alginic acid-added seaweed drink (Haezomiin) in brown algae (Undaria pinnatifida) on obesity and biological activity of SD rats. Korean J Life Sci 7: 361-370.   과학기술학회마을
9 Jang MA, Lee KS, Seo JS, Choi YS. 2002. Effects of dietary supplementation of sea tangle extracts on the excretion of neutral steroids and bile acid in diabetic rats. J Korean Soc Food Sci Nutr 31: 819-925   과학기술학회마을   DOI   ScienceOn
10 Kannel WB, Wilson PWF. 1995. An update on coronary risk factors. Med Clin North Am 79: 951-956.
11 Son HS, Kim HS, Ju JS. 1992. Effect of seaweed intake on the absorption of sodium, calcium, potassium and hypolipidemic mechanism in healthy male subjects. J Korean Soc Food Nutr 21: 471-477.   과학기술학회마을
12 Lee KS, Seo JS, Choi YS. 1998. Effect of sea tangle and hypoglycemic agent on lipid metabolism in diabetic rats. J Korean Soc Food Sci Nutr 27: 960-967.   과학기술학회마을
13 보건복지부. 1997. 1997년도 국민 영양 조사 결과서. 문영사, 서울. p 37.
14 Ichida T. 1963. The effect of cholesterol-feeding on the tissue lipids. Hokkaido J Med Sci 38: 57-63.
15 Ross R. 1986. The pathogenesis of atherosclerosis, An update. New Engl J Med 314: 488-494.   DOI   ScienceOn
16 Wang C, Yang G. 1997. Comparison of effects of two kinds of soluble algae polysaccharide on blood lipid, liver lipid, platelet aggregation and growth in rats. NCBI 31: 342-345.
17 Richmond W. 1976. Use of cholesterol oxidase for assay of total and free cholesterol in serum by continuous flow analysis. Clin Chem 22: 1579-1584.
18 Lee JG, Lim YS, Joo DS, Joung IH. 2002. Effects of diet with seatangle (Kjellmaniella crassifolia) on calcium absortion, serum composition and feces in rats. J Korean Fish Soc 35: 601-607   과학기술학회마을
19 Chen PS, Toribara TY, Warnerm H. 1956. Microdetermination of phosphorus. Anal Chem 28: 1756-1760.   DOI
20 Noma A, Nakayama KN, Kota M, Okabe H. 1978. Simul taneous determination of serum cholesterol in high and low density lipoprotein with use of heparin, $Ca^{2+}$ and an anion exchange resin. Clin Chem 24: 1504-1511.
21 Frings CS, Dunn RJ. 1970. A colorimetric method for determination of total serum lipids based on the sulfophosphovanillin reaction. Am J Clin Path 53: 89-92.