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http://dx.doi.org/10.3746/jkfn.2003.32.7.1164

Detection of Aristolochic Acid from Medicinal Herbs Marketed  

강숙경 (충남대학교 식품공학과)
송경빈 (충남대학교 식품공학과)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.32, no.7, 2003 , pp. 1164-1167 More about this Journal
Abstract
Aristolochic acid has been known to be a carcinogenic compound and to cause Chinese herbs nephrophathy(CHN). To determine the content of aristolochic acid in various medicinal herbs marketed domestically, samples of Aristolochia fangchi, Aristolochia fructus, Aristolochia radix, Asiasari radix, Saussureae radix, and Akebia caulis were analyzed using TLC and HPLC. The optimal conditions for TLC and HPLC using $C_{18}$ column were established for the quantitative analysis of aristolochic acid. This study showed that Aristolochia fangchi and Aristolochia fructus examined in this study contain aristolochic acid of 3.9 and 2.3 mg/g sample, respectively. In contrast, aristolochic acid was not detected in the other samples.
Keywords
aristolochic acid; Aristolochia fangchi; detection; HPLC;
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