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http://dx.doi.org/10.3746/jkfn.2002.31.5.899

Antimicrobial Activities of Combined Extract of Aloe vera with Propolis against Oral Pathogens  

임지영 (서울여자대학교 자연과학부)
문유선 (서울여자대학교 자연과학부)
정승희 (서울여자대학교 자연과학부)
이규임 (서울여자대학교 자연과학부)
유수연 (서울여자대학교 자연과학부)
박원봉 (서울여자대학교 자연과학부)
심창섭 (김정문 알로에 과학연구소)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.31, no.5, 2002 , pp. 899-904 More about this Journal
Abstract
Aloe and propolis are extensively used in folk medicine. Ethanol extracts of Aloe vera (AE), ethanol extract of propolis (PE) and waxfree extract of propolis (PW) were prepared to test antimicrobial activities against five oral microorganisms (Streptococcus mutans, Enterococcus faecalis, Enteococcus hirae, Escherichia coli, Candida albicans). Antimicrobial activities were tested by serial broth dilution method and expressed by minimal inhibitory concentration (MIC). The AE showed relatively weak antimicrobial activities, while both of PE and PW greatly inhibited all microorganisms tested. To investigate the antimicrobial effects of the combined extracts of aloe with propolis, the fractional inhibitory concentration index (FICI) was determined by checkerboard assay for each strain. The combination of AE with PE or PW resulted in Synergistic effect against oral microorganisms tested (FICI=0.375) except Escherichia coli (FICI=1.0 for PE, FICI=0.75 for PW).
Keywords
Aloe vera; propolis; oral pathogens; antimicrobial; synergistic;
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