Immunostimulatory effects of enzymatic porcine placental hydrolyzate against cyclophosphamide-induced immunosuppressed model |
Kim, Keun Nam
(Unimed Pharm Inc.)
Kim, Min Ju (Unimed Pharm Inc.) Yoon, Sun Myung (Unimed Pharm Inc.) Kwon, Min Joo (Invivo Co. Ltd.) Shin, Dong Yeop (Invivo Co. Ltd.) Lee, Hak Yong (Invivo Co. Ltd.) Park, Young Mi (Invivo Co. Ltd.) |
1 | Banerjee KK, Bishayee A, Chatterjee M. Anti-inflammatory effect of human placental extract: a biochemical mechanistic approach. Riv. Eur. Sci. Med. Farmacol. 14: 361-366 (1992) |
2 | Cesta MF. Normal structure, function, and histology of the spleen. Toxicol. Pathol. 34: 455-465 (2006) DOI |
3 | Choi JH, Lee EB, Park YG, Lee HK, Jang HH, Choe JS, Hwang KA, Park SY, Hwang IG, Hong HC, Lee HJ, Jeong HC, Lim HJ, Lee SH. Aged doraji (Platycodon grandiflorum) ameliorates cyclophosphamide-Induced immunosuppression in mice. Kor. J. Pharmacogn. 50: 219-225 (2019) |
4 | Davis L, Kuttan G. Effect of Withania somnifera on cytokine production in normal and cyclophosphamide treated mice. Immunopharmacol. Immunotoxicol. 21: 695-703 (1999) DOI |
5 | Han NR, Kim KY, Kim MJ, Kim MH, Kim HM, Jeong HJ. Porcine placenta mitigates protein-energy malnutrition-induced fatigue. Nutrition. 29: 1381-1387 (2013) DOI |
6 | Hong SH, Kwon MJ, Lee HY, Park YM, Shin DY, Choi JS, Kim MJ, Yang HJ, Shin NR. Immunomodulatory effect of fermented vinegar on cyclophosphamide-induced immunosuppression model. J. Food Nutr. Res. 9: 469-476 (2021) DOI |
7 | Hussain A, Shadma W, Maksood A, Ansari SH. Protective effects of Picrorhiza kurroa on cyclophosphamide-induced immunosuppression in mice. Pharmacognosy Res. 5: 30-35 (2013) DOI |
8 | Kiladjian JJ, Bourgeois E, Lobe I, Braun T, Visentin G, Bourhis JH, Fenaux P, Chouaib S, Caignard A. Cytolytic function and survival of natural killer cells are severely altered in myelodysplastic syndromes. Leukemia. 20: 463-470 (2006) DOI |
9 | Kim JH, Lee JW, Kim YI, Lee MH. The effect of placental extract on the expression of tyrosinase, TRP-1 and TRP-2 in SK30 melanoma cells. J. Kor. Derma. Assoc. 41: 1612-1618 (2003b) |
10 | Chen F, Huang G. Preparation and immunological activity of polysaccharides and their derivatives. Int. J. Biol. Macromo. 7: 211-216 (2018) DOI |
11 | Taguchi T. Induction chemotherapy for solid tumors. Gan To Kagaku Ryoho. 40: 679-683 (2013) |
12 | Ozkok A, Kaymaz S, Elcioglu OC, Bakan A, Odabas AR. Cyclophosphamide induced early-onset interstitial lung disease. CEN Case Rep. 1: 128-129 (2012) DOI |
13 | Rasmussen L, Arvin A. Chemotherapy-induced immunosuppression. Environ. Health Perspect. 43: 21-25 (1982) DOI |
14 | Shalit I, Kletter Y, Halperin D, Waldman D, Vasserman E, Nagler A, Fabian I. Immunomodulatory effects of moxifloxacin in comparison to ciprofloxacin and G-CSF in a murine model of cyclophosphamide- induced leukopenia. Eur. J. Haematol. 66: 287-296 (2001) DOI |
15 | Wang K, Conlon M, Ren W, Chen BB, Baczek T. Natural products as targeted modulators of the immune system. J. Immunol. Res. 7862782 (2018) DOI |
16 | Zhang M, Liu X, Li J, He L, Tripathy D. Chinese medicinal herbs to treat the side-effects of chemotherapy in breast cancer patients. Cochrane Data. Syst. Rev. 18: CD004921 (2007) |
17 | Bourke CD, Berkley JA Prendergast AJ. Immune dysfunction as a cause and consequence of malnutrition. Trends Immunol. 37: 386-398 (2016) DOI |
18 | Chen XG, Huang H, Tian Y, Guo CC, Liang CY, Gong YL, Zou BY, Cai RQ, Lin TY. Cyclosporine, prednisone, and high-dose immunoglobulin treatment of angioimmunoblastic T cell lymphoma refractory to prior CHOP or CHOP-like regimen. Chin. J. Cancer. 30: 731-738 (2011) DOI |
19 | Haddad PS, Azar GA, Groom S, Boivin M. Natural health products, modulation of immune function and prevention of chronic diseases. Evid. Based Complement. Alternat. Med. 2: 513-520 (2005) DOI |
20 | Hoffman WP, Ness DK, Van Lier RB. Analysis of rodent growth data in toxicology studies. Toxicol. Sci. 66: 313-319 (2002) DOI |
21 | Mitsui Y, Bagchi M, Marone PA, Moriyama H, Bagchi D. Safety and toxicological evaluation of a novel, fermented, peptideenriched, hydrolyzed swine placenta extract powder. Toxicol. Mech. Methods. 25: 13-20 (2015) DOI |
22 | Yu Q, Nie SP, Wang JQ, Liu XZ, Yin PF, Huang DF, Li WJ, Gong DM, Xie MY. Chemoprotective effects of Ganoderma atrum polysaccharide in cyclophosphamide-induced mice. Int. J. Biol. Macromol. 64: 395-401 (2014) DOI |
23 | Zhou Y, Chen X, Yi R, Li G, Sun P, Qian Y, Zhao X. Immunomodulatory effect of Tremella polysaccharides against cyclophosphamide-induced immunosuppression in Mice. Molecules 23: 239 (2018) DOI |
24 | Jeong DY, Yang HJ, Jeong SJ, Shin DY, Lee HY, Park YM. Immunoregulatory activities of blueberry yeast fermented powder in immunosuppressed model. J. Korean Soc. Food Sci. Nutr. 49: 433-443 (2020) DOI |
25 | Kotas, M.E. Medzhitov R. Homeostasis, inflammation, and disease susceptibility. Cell. 160: 816-827 (2015) DOI |
26 | Lin ZB, Zhang HN. Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms. Acta. Pharmacol. Sin. 25: 1387-1395 (2004) |
27 | Miyauchi A. Hiramine C, Tanaka S. Hojo, K. Differential effects of a single dose of cyclophosphamide on T cell subsets of the thymus and spleen in mice: flow cytofluorometry analysis. Tohoku J. Exp. Med. 162: 147-167 (1990) DOI |
28 | Kumar S, Kanti B, Liaquat A, Biswapati M. Anti-inflammatory and antiplatelet aggregation activity of human placental extract. Act. Pharmacol. Sini. 24: 187-192 (2003) |
29 | Kumar S, Sharma G, Sidiq T, Khajuria A, Jain M, Bhagwat D, Dhar KL. Immunomodulatory potential of a bioactive fraction from the leaves of Phyllostachys bambusoides (bamboo) in BALB/c mice. EXCLI J. 13: 137-150 (2014) |
30 | McKallip RJ, Lombard C, Martin BR, Nagarkatti M, Nagarkatti PS. Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo. J. Pharmacol. Exp. Ther. 302: 451-465 (2002) DOI |
31 | Xun CQ. Thornpson JS, Jennings CD, Brown SA, Widrner MB. Effects of total body irradiation, busulfan-cyclophosphamide, or cyclophosphamide conditioning on inflammatory cytokine release and development of acute and chronic graft versus-host disease in H-2-incompatible transplanted SCID mice. Blood 83: 2360-2367 (1994) DOI |
32 | Han NR, Park CL, Kim NR, Kim HY, Yoou MS, Nam SY, Moon PD, Jeong HJ, Kim HM. Protective effect of porcine placenta in a menopausal ovariectomized mouse. Reproduction. 150: 173-181 (2015) DOI |
33 | Kim DW, Chung KT. Ulmus macrocarpa hance reduces cyclophosphamide- induced toxicity in mouse liver. J. Life Sci. 31: 223-228 (2021) DOI |
34 | Kim HJ, Lee JW, Kim YL, Lee MH. The effect of placental extract on the expression of tyrosinase, TRP-1 and TRP-2 in SK30 melanoma cells. Korean J. Dermatol. 41: 1612-1618 (2003a) |
35 | Rehman MU, Tahir M, Ali F, Qamar W, Lateef A, Khan R, Quaiyoom A, Hamiza OO, Sultana S. Cyclophosphamide-induced nephrotoxicity, genotoxicity, and damage in kidney genomic DNA of Swiss albino mice: the protective effect of Ellagic acid. Mol. Cell Biochem. 365: 119-127 (2012) DOI |
36 | Noh EM, Kim JM, Lee HY, Song HK, Joung SO, Yang HJ, Kim MJ, Lim KS, Lee YR. Immuno-enhancement effects of Platycodon grandiflorum extracts in splenocytes and a cyclophosphamide induced immunosuppressed rat model. BMC Complement. Altern. Med. 19: 322 (2019) DOI |
37 | Ooi VE, Liu F. Immunomodulation and anti-cancer activity of polysaccharide- protein complexes. Curr. Med. Chem. 7: 715-729 (2000) DOI |
38 | Koo SW, Lim MK, Lee KW. Immunomodulatory effects of Zingiber officinale in cyclophosphamide-induced immunosuppress mice. J. Vet. Clin. 32: 56-61 (2015) DOI |
39 | Park YM, Lee HY, Shin DY, Lee YH, Yang YJ, Lee HS, Lee JO, Choi KS, Kang JH, Cho YH, Kim MG, Yun CY, Kim MJ, Jang DJ, Yang HJ, Lee YR. Immunostimulatory activity of black rice bran in cyclophosphamide-induced immunosuppressed rats. Nat. Prod. Commun. 15: 1-11 (2020) |
40 | Pizzolo G, Trentin L, Vinante F, Agostini C, Zambello R, Masciarelli M, Feruglio C, Dazzi F, Todeschini G, Chilosi M, Veneri D, Zanotti R, Benedetti F, Perona G, Semenzato G. Natural killer cell function and lymphoid subpopulations in acute non-lymphoblastic leukaemia in complete remission. Br. J. Cancer. 58: 368-372 (1988) DOI |
41 | Rosenthal M. The application of an extract of human placenta in the treatment of rheumatic affections. Int. J. Tiss. Reac. 4: 147-151 (1982) |
42 | Son CG, Han SH, Cho JH, Shin JW, Cho CH, Lee YW. Induction of hemopoiesis by saenghyuldan, a mixture of Ginseng radix, Paeoniae radix alba, and Hominis placenta extracts. Acta. Pharmacol. Sin. 24: 120-126 (2003) |
43 | Tiwary S, Shukla D, Tripathi A, Agrawal S, Singh M, Shukla V. Effect of placental-extract gel and cream on non-healing wounds. J. Wound Care. 15: 325-328 (2006) DOI |
44 | Togashi, S., Takahashi, N., Iwama, M., Watanabe, S., Tamagawa, K., and Tetsuya, F. Antioxidative collagen-derived peptides in humanplacenta extract. Placenta 23: 497-502 (2002) DOI |
45 | Shokrzadeh M, Chabra A, Ahmadi A, Naghshvar F, Habibi E, Salehi F, Assadpour S. Hepatoprotective effects of Zataria multiflora ethanolic extract on liver toxicity induced by cyclophosphamide in mice. Drug Res. 65: 169-175 (2015) DOI |