Browse > Article
http://dx.doi.org/10.9721/KJFST.2011.43.5.655

Characteristic Changes of Galgeuntang Fermented with Lactic Acid Bacteria  

Rhee, Young-Kyoung (Research Division for Food Industry Advancement, Korea Food Research Institute)
Kim, Mi-Hyun (Research Division for Food Industry Advancement, Korea Food Research Institute)
Lee, Young-Chul (Research Division for Food Industry Advancement, Korea Food Research Institute)
Rho, Jeong-Hae (Research Division for Food Industry Advancement, Korea Food Research Institute)
Ma, Jin-Yeul (TKM Integrated Research Division, Korea Institute of Oriental Medicines)
Cho, Chang-Won (Research Division for Food Industry Advancement, Korea Food Research Institute)
Publication Information
Korean Journal of Food Science and Technology / v.43, no.5, 2011 , pp. 655-658 More about this Journal
Abstract
The possible application of Lactobacillus spp. as a functional starter culture to ferment galgeuntang (GT) and to produce bioactive isoflavone (daidzein) was investigated. Lactobacillus casei KFRI 127, L. plantarum KFRI 144, L. bulgaricus KFRI 344 were used for GT fermentation. Acid development and quantification of isoflavones using high-performance liquid chromatography were performed after fermentation at 37$^{\circ}C$ for 48 h. All the tested Lactobacillus spp. lowered pH to about 3.8 in 48 h and L. plantarum KFRI 144 exhibited 89.9% hydrolysis rate of daidzin (79.1-8.0 ${\mu}g$/mL) during fermentation. The content of daidzein in GT fermented with L. plantarum KFRI 144 was increased by 6.6-fold (3.6-23.9 ${\mu}g/mL$). These results demonstrate that L. plantarum KFRI 144 has potential as functional starter culture for manufacturing fermented GT with higher isoflavone bioavailability.
Keywords
Lactobacillus; galgeuntang; isoflavone; fermentation;
Citations & Related Records
Times Cited By KSCI : 8  (Citation Analysis)
Times Cited By SCOPUS : 1
연도 인용수 순위
1 Pyo YH, Lee TC, Lee YC. Enrichment of bioactive isoflavones in soymilk fermented with $\beta$-glucosidase-producing lactic acid bacteria. Food Res. Int. 38: 551-559 (2005)   DOI   ScienceOn
2 Kim DH. Herbal Medicinal Microbiology. HYOIL Books, Seoul, Korea. pp. 147-150 (2000)
3 Park EK, Shin J, Bae EA, Lee YC, Kim DH. Intestinal bacteria activates estrogenic effect of main constituents puerarin and daidzin of Pueraria thunbergiana. Biol. Pharm. Bull. 29: 2432-2435 (2006)   DOI   ScienceOn
4 Eum HA, Lee JH, Yang MC, Shim KS, Lee JH, Ma JY. Protective effect of ssanghwa-tang fermented by Lactobacillus fermentum against carbon tetrachloride-induced acute hepatotoxicity in rats. Afr. J. Tradit. Complement. Altern. Med. 8: 312-321 (2011)
5 Bae EA, Han MJ, Kim EJ, Kim DH. Transformation of ginseng saponins to ginsenoside Rh2 by acids and human intestinal bacteria and biological activities of their transformants. Arch. Pharm. Res. 27: 61-67 (2004)   DOI
6 Weon JB, Ma JY, Yang HJ, Ma CJ. Neuroprotective activity of fermented Oyaksungisan. Korean J. Pharmacogn. 42: 22-26 (2011)
7 Masood MI, Qadir MI, Shrazi JH, Khan IU. Beneficial effects of lactic acid bacteria on human beings. Crit. Rev. Microbiol. 37: 91-98 (2011)   DOI   ScienceOn
8 Lee JY, Park YS, Kim YS, Shin DH. Antimicrobial characteristics of metabolites of lactic acid bacteria isolated from feces of newborn baby and from Dongchimi. Korean J. Food Sci. Technol. 34: 472-479 (2002)
9 Walsh KR, Failla ML. Transport and metabolism of equol by Caco-2 human intestinal cells. J. Agr. Food Chem. 57:8297-8302 (2009)   DOI   ScienceOn
10 Chien HL, Huang HY, Chou CC. Transformation of isoflavone phytoestrogens during the fermentation of soymilk with lactic acid bacteria and bifidobacteria. Food Microbiol. 23: 772-778 (2006)   DOI   ScienceOn
11 Cho YH, Imm JY, Kim HY, Hong SG, Hwang SJ, Park DJ, Oh S. Isolation and partial characterization of isoflavone transforming Lactobacillus plantarum YS712 for potential probiotic use. Korean J. Food Sci. An. Resour. 29: 640-646 (2009)   DOI
12 Wang G, Kuan SS, Francis OJ, Ware GM, Carman AS. A simplified HPLC method for the determination of phytoestrogens in soybean and its processed products. J. Agr. Food Chem. 38: 185- 190 (1990)   DOI
13 Um YR, Lee JH, Lee JH, Moon HJ, Park HY, Cho CW, Ma JY. Acute toxicity study on fermented ojeoksan (wujisan) extract in mice. J. Oriental Obstet. Gynecol. 22: 19-27 (2009)
14 Jung YJ, Han DO, Choi BH, Park C, Lee H, Kim SH, Hahm DH. Effect of fermented herbal extracts, HP-1 on enzyme activities and gene expressions related to alcohol metabolism in ethanol- loaded rats. Korean J. Oriental Physiol. Pathol. 21: 387-391 (2007)
15 Lee JH, Lee JH, Ma CJ, Ma JY. Single dose toxicity study on galgeuntang in mice. Korean J. Oriental Med. 15: 79-83(2009)
16 Pyo YH, Lee TC, Lee YC. Effect of lactic acid fermentation on enrichment of antioxidant properties and bioactive isoflavones in soybean. J. Food Sci. 70: S215-S220 (2005)
17 Jeon KS, Ji GE, Hwang IK. Assay of $\beta$-glucosidase activity of bifidobacteria and hydrolysis of isoflavone glycosides by Bifidobacterium sp. Int-57 in soymilk fermentation. J. Microbiol. Biotechn. 12: 8-13 (2002)
18 Wang CY, Huang HY, Kuo KL, Hsieh YZ. Analysis of Puerariae radix and its medicinal preparations by capillary electrophoresis. J. Chromatogr. A 802: 225-231 (1998)   DOI
19 Fuller R. Probiotics in man and animals. J. Appl. Bacteriol. 66: 365-378 (1989)   DOI
20 Choi YB, Woo JG, Noh WS. Hydrolysis of $\beta$-glucosidase bonds of isoflavone conjugates in the lactic acid fermentation of soymilk. Korean J. Food Sci. Technol. 31: 189-195 (1999)
21 Murota K, Shimizu S, Miyamoto S, Izumi T, Obata A, Kikuchi M, Terao J. Unique uptake and transport of isoflavone aglycones by human intestinal caco-2 cells: Comparison of isoflavonoids and flavonoids. J. Nutr. 132: 1956-1961 (2002)
22 Park SY, Baek JM, Baek SH. Cytoprotective effect of galgeuntang extract on cadmium-induced cytotoxicity. Yakhak Hoeji 54: 151-156 (2010)
23 Shin JM, Kim YO, Baek SH. Free radical scavenging activity and kinetic behavior of the galgeuntang water extract. Oriental Pharm. Exp. Med. 8: 32-38 (2008)   DOI
24 Ji X, Tan BK, Zhu YC, Linz W, Zhu YZ. Comparison of cardioprotective effects using ramipril and danshen for the treatment of acute myocardial infarction in rats. Life Sci. 73: 1413-1426 (2003)   DOI   ScienceOn