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Effects of Defatted Soybean Grits on Lipid Metabolism in Rats Fed with High-fat Diet  

Kim, Hyun-Jeong (The Center for Traditional Microorganism Resources, Keimyung University)
Ji, Young-Ju (Department of Food and Technology, Keimyung University)
Lee, Sung-Gyu (Department of Food and Technology, Keimyung University)
Choi, Jun-Hyeok (Department of Food and Technology, Keimyung University)
Lee, Eun-Ju (Bio Research Institute, NUC Electronics Co. Ltd.)
Jeong, Hyun-Jin (Bio Research Institute, NUC Electronics Co. Ltd.)
Lee, Sam-Pin (The Center for Traditional Microorganism Resources, Keimyung University)
Lee, In-Seon (Department of Food and Technology, Keimyung University)
Publication Information
Korean Journal of Food Science and Technology / v.40, no.5, 2008 , pp. 580-585 More about this Journal
Abstract
The principal objective of this study was to determine the effects of defatted soybean grits (DSG) on body lipidmetabolism with 4 weeks of feeding on a high-fat diet. The rats were divided into the following 4 groups: control group (Con), control group treated with 20% DSG (C20D), high-fat group (HF), and high-fat group treated with 20% DSG (HF20D). The plasma total cholesterol and LDL-cholesterol concentrations were significantly lower in the HF20D group than in the HF group. On the other hand, the DSG supplement resulted in a significant increase in plasma HDL-cholesterol levels. The DSG supplement reduced the hepatic total lipid, total cholesterol, and triglyceride contents as compared to what was observed in the HF diet groups. In addition, the fecal total cholesterol and triglyceride contents increased in the DSG treatment groups. The hepatic HMG-CoA reductase activities were demonstrated to be significantly lower in the HF20D group than in the HF group. These results showed that the DSG powder lowered plasma cholesterol levels, tissue lipid contents, and cholesterol accumulation in the rats.
Keywords
defatted soybean grits; high-fat diet; cholesterol; lipid profiles;
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