Antioxidantive, Phospholipase Inhibiting, and Anticancer Effect of Polyphenol Rich Fractions from Panax ginseng C. A. Meyer |
Choi, Hee-Jin
(Department of Food Science & Technology College of Natural resources Yeungnam University)
Han, Ho-Suk (Department of Food Science & Technology College of Natural resources Yeungnam University) Park, Jung-Hye (Department of Food Science & Technology College of Natural resources Yeungnam University) Son, Jun-Ho (Korea Advanced Food Research Institute) Bae, Jong-Ho (Department of Confectionery Decoration, Daegue Mirae College) Seung, Tae-Su (Department of Food & Nutrition, Changwon Junior College) Choi, Cheong (Department of Food Science & Technology College of Natural resources Yeungnam University) |
1 | Korea ginseng. (1993) In AnnuaI Report of Korean ginseng & tobacco research institute, pp. 1-6 |
2 | Park, C. W. (1984) The studies of pharmacology of ginseng. Biochemistry News 4, 37-56 |
3 | Lee, H. O. and Park, O. J. (1998) Antioxidant effects of phenolic acid and ginseng extract in aqueous system. Korean J. Food Sci. Technol. 30, 34-438 |
4 | Han, B. H. and Park, M. H. (1978) Studies on the antioxidant components of Korean ginseng (II). Biochem. J. 9, 169-171 |
5 | Kawashima, S. (1969) The possible role of lipoperoxide in aging. Nagoya J. Med. Sci. 32, 303-326 |
6 | Tien, M. and Aust, S. D. (1981) Superoxide dependent lipid peroxidation. Fed. Proc. 40, 179-182 |
7 | Fridovich, I. (1986) Biological effect of the superoxide radical irwin fridovich. Arch. Biochem. Biophy. 247, 1-11 DOI PUBMED ScienceOn |
8 | Tanaka, K., Aiita, H. and Inoue, K. (1993) Phospholipase inhibitiors. Prot. Nucl. Acid Enzym. 38, 1988-1999 |
9 | Hwang, W. I. and Soo, K. O. (1984) A study on the anticancer actives of lipid soluble ginseng extract and ginseng saponin derivatives against some cancer cells. Korean J. Ginseng Sci. 8, 153-166 |
10 | Kim, S. I. (1988) Studies on the cytotoxic components of the Korean ginseng root, Ph. D. Thesis, Chungnam National University, Daejeon, Korea |
11 | Buege, J. A. and Aust, S. D. (1978) Microsomal lipid peroxidation. Methods Enzymol. 105, 302-305 |
12 | Blois, M. S. (1958) Antioxidant determination by the use of a stable free radical. Nature 26, 1198-1199 |
13 | Dole, V. P. and Meinertz, H. (1960) Microdetermination of long-chain fatty acids in plasma and tissues. J. Biol. Chem. 235, 2595-2599 |
14 | Dariusz, S., Sarah, J. S. Richard, H. C. and Michael, B. (1960) An improved MTT assay. J. Immuno. Methods 157, 203-207 |
15 | Hwang, W. I. and Cha, S. M. (1978) A cytotoxic activity of extract of panax ginseng root aginst some cancer cell. In proc. 2nd Int. Ginseng Symp. pp. 47-52 |
16 | Hwang, W. I. and Oh, S. K. (1984) A study on the anticancer actives of lipid soluble ginseng extract and ginseng saponin derivatives against some cancer cells. Korean J. Ginseng Sci. 8, 153-166 |
17 | Hagiwara, N., Tateishi, M., Kim, M., Yamane, T. and Takashi, T. (1994) In Proceeding of the international symposium on tea science: Inhibition of axoxymethane-mduced colon carcinogensis in rat by tea polyphenols. Seoul, Korea. pp. 190-194 |
18 | Brekhman, I. I. (1957) Gosudarst Isdat et Med. Lit. Leningrad. 1-18 |
19 | Han, B. H., Park, M. H., Woo, L. K., Woo, W. S. and Han, Y. N. (1979) Studies on the antioxidant components of Korean ginseng (I). Korean Biochem. J. 12, 33-40 |
20 | Hwang, W. I. and Soo, K. O. (1986) Effects of petroleum extract of ginseng root on some enzyme activity in human colon cancer cells. Korean J. Ginseng Sci. 10, 27-35 |
21 | Lee, S. H. and Hwang, W. I. (1986) Inhibitory effect of petroleum ether extract of panax ginseng root against growth of human cancer cells. Korean J. Ginseng Sci. 10, 141-150 |
22 | Jin, H. K., Kim, S. H. and Lee, J. K. (1982) Studies of the physiologcal activity of Korean ginseng. Kor. J. Appl. Microbiol. Bioeng. 10, 101-108 |
23 | Choi, H. J., Zhang, Y. B., An, B. J. and Choi, C. (2002) Identification of biologically active compounds from panax gingeng C. A. Meyer. Korean J. Food Sci. Technol. 34, 493-497 |
24 | Park, T. H., Hong, J. T. and Hong, S. Y. (1982) Studies oh the antioxygenic substances in panxa gingeng roots. Korean Food Sci. Technol. 14, 130-135 |
25 | Fricovich, I. (1989) Superoxide dimutases. J. BioI. Chem. 264, 7761-7764 |
26 | Wee, J. J. (1989) Isolation and identification ofconsdtuents from antioxidant and hematopoietic fracdons of panax ginseng C. A. Meyer. Ph. D. Thesis, Seoul National University, Seoul, Korea |
27 | Babizhayev, M. A., Seguin, M. C., Gueyne, J., Evstigneeva, R. P., Ageyeva, E. A. and Zheltukhina, G. A. (1994) L-camosine (-alanyl-L-histidine) and carcinine (-alanylhistamine) act as natural antioxidants with hydroxyl radical-scavenging and lipid-peroxidase activities. Biochem. J. 304, 509-913 DOI |
28 | Kim, S. M., Cho, Y. S. and Sung, S. K. (1999) Effect of ethonol extracts in pinus densiflora, lithospermum erythrohizon on the lipid oxidation of oil emulsion. J. Korean Soc. Food Sci. Nutr. 28, 984-989 |
29 | Han, B. H. and Park, M. H. (1978) Studies on the antioxidant components of Korean ginseng (II). 9, 169-171 |
30 | Hwang, W. I. and Oh, S. K. (1984) A study on the anticancer acitvites of lipid soluble ginseng extract and ginseng saponin derivatives against some cancer cells. Korean J. Ginseng Sci. 8, 153-166 |
31 | Masataka, Y. and Keiko, M. (1998) Interaction of iron with polyphenolic compounds, application to antioxidant characterization. Anal. Biochem. 257, 40-44 DOI ScienceOn |
32 | Addis, P. B. (1986) Occurrence of lipid oxidation products in foods. Food Chem. Toxicol. 24, 1021-1030 DOI |
33 | Chan, W. K. M., Decker, E. A., Lee, J. B. and Butterfield, D. A. (1994) EPR spintrapping studies of the hydroxyl radical scavening activity of carnosine and related dipeptides. J. Agric. Food Chem. 42, 1407-1410 DOI ScienceOn |
34 | Dennis, E. A. and Boyer, P. D. (1983) The enzymes. Academic press, New York. 16, pp. 307-353 |
35 | Park, J. D., Kim, M. W. and Wee, J. J. (1987) Isolation and identification of free phenolic acids in Korean ginseng. Korean J. Food Sci. Technol. 19, 392-396 |
36 | Harman, D. Aging. (1956) A theory based on free radical and radiation chemistry. J. GervntoI 11, 298-300 |
37 | Kim, J. W., Song, K. S., Chang, H. W., Yu, S. H. and Yoo, I. D. (1995) A phospho-lipase , inhibitior isolated from umgilicaria esculenta. Kor. J. Appl. Microbiol. Biotechnol. 23, 526-530 |
38 | Lee, J. W., Do, J. H. and Shim, K. H. (1999) Antioxidant activity of the water soluble brewing reaction prducts isolated from Korean red scavenging. J. Ginseng Res. 23, 176-181 |
39 | Lee, S. H. and Min, D. B. (1990) Effects, quenching mechanisms and kinetics of carofenoids in chlorophlly sensitized photooxidation of soybean oil. J. Agric Food Chem. 38, 1630-1634 DOI |
40 | Thomas, C., Glenn, F. V. and Christione, C. W. (1993) The hydrolysis product of icre-187 promotes iron-catalysed hydroxylradical production via the fenton reaction. Biochem. Pharmacol. 15, 1967-1972 |
41 | Kim, J. W., Song, K. S., Yoo, I. D., Chang, H. W., Yu, S. H., Bae, K. G. and Min, T. J. (1996) Two phenolic compounds isolated from umgilicaria esculenta as phospholipase inhibitors. Korean J. Mycotogy 24, 237-242 |
42 | Kim, J. W., Song, K. S. and Chang, H. W. (1995) A phospholipase inhibitor isolated form umbilicaria esclenta. Kor. J. Appl. Microbiol. Biotechnol. 23, 526-530 |
43 | Han, B. H., Park, M. H. and Han, Han, Y. N. (1985) Studies on the antioxidant components of Korean ginseng. Korean Biochem. J. 18, 337-340 |
44 | Garriques, S. S. (1854) On panaquilon, a new vegetable substance. Ann. Chem. Pharm. 40, 231-233 |
45 | Park, M. H. (1998) EfFect of polyphenol compounds from persimmon leaves (Diospyros kaki folium) on immunofunctional and biological activity, Ph. D. Thesis, Yeungnam University, Kyungsan, Korea |
46 | Han, B. H., Park, M. H. and Han, Y. N. (1985) Studies on antioxidant components of Korean ginseng (V): The mechanism of antioxidant activity of maltol and phenolic acid. Korean Biochem. J. 18, 337-340 |
47 | Lee, H. O. and Park, O. J. (1998) Antioxidant effects of phenolic acid and ginseng extract in aqueous system. Korean J. Food Sci. Technol. 30, 434-438 |
48 | Kim, M. W., Choi, Y. J., Cho, Y. H. and Hong, S. K. (1980) Study on the components of the anti-oxidant activity of panax ginseng. J. Korean Agri. Chem. Soci. 23, 173-177 과학기술학회마을 |
49 | Han, B. H. (1972) Current status of Korean ginseng research. Kor. J. Pharmacog. 3, 151-160 |
50 | Minotti, G. and Ausst, S. D. (1987) The requirement for iron (III) in the initation of lopod peroxidadon by iron (II) and hydrogen peroxide. J. Biol. Chem. 262, 1098-1104 |
51 | Han, B. H., Park, M. H and Han, Y. N. (1985) Studies on antioxidant components of Korean ginseng (V). The mechanism of antioxidant activity of maltol and phenolic acid. Korean Biochem. J. 18, 337-340 |
52 | Hwang, W. I. and Oh, S. K. (1996) Effects of petroleum extract of ginseng root on some enzyme activity in human colon cancer cell. Korean J. Ginseng Sci. 10, 27-35 |
53 | Dicker, E. A., Cmm, A. D. and Calvert, J. T. (1992) Differences in the antioxidant mechanism of carmosine in the prescence of copper and iron. J. Agric. Food Chem. 40, 756-759 DOI |
54 | Han, B. H., Park, M. H., Woo, L. K., Woo, W. S. and Han, Y. N. (1979) Studies on the antioxidant components of Korean ginseng (I). Korean Biochem. J. 12, 33-40 |
55 | Kang, Y. H., Park, Y. K. and Lee, G. D. (1996) The nitric scavenging and electron donating ability of phenolic compounds. Korean J. Food Sci. Technol. 28, 232-239 |
56 | Ko, S. R. (1993) Comparative study onchemical components and biological activities of panax species, Ph. D. Thesis, Chonbuk National Unuversity, Chonju, Korea |