Browse > Article

Bioaccumulation of Herbicide Butachlor in Killifish  

Kim, Yong-Hwa (Toxicology Reseach Team. Korea Research Institute Chemical Technology)
Kim, Kyun (Toxicology Reseach Team. Korea Research Institute Chemical Technology)
Publication Information
Applied Biological Chemistry / v.45, no.1, 2002 , pp. 30-36 More about this Journal
Abstract
A bioconcentration experiment was performed for killifish using nonradioactive and radioactive butachlor. At 0.036 ppm concentration, the highest bioconcentration ratio $(C_f/C_w)$ and BCF at steady state recorded as 296 and 87 respectively. And at 0.0036 ppm concentration, the highest $C_f/C_w$ ratio was 169 and the BCF was 51 at steady state. Considering the experimental variation of the BCF's, the BCF of butachlor was tentatively determined to be $69{\pm}28$. And the $^{14}C-butachlor$ and its metabolites depurated about 50% within 12 hours and 90% within 30 hours after depuration experiment started. And in vivo metabolites, designated as M-I, M-II, and M-III, were found in killifish and the excretes as butachlor was metabolised.
Keywords
bioconcentration; butachlor; killifish; BCF; $^{14}C-butachlor$; metabolites; depuration; $R_f$;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Hitch, R. K. (1982) Pesticide Assessment Guidelines, Subdivision N Chemistry: Environmental Fate, U.S. EPA Washington D.C. pp. 103-106
2 農藥工業會(日本)(1982)農藥登錄申誇請の責務書, 農藥エ業倉會, 東京p.99-151
3 Chun Chul Shin, Sung Kyu Lee, Young Bae Kim, Yong-Hwa Kim and Jung Koo Roh (1987) Changes in susceptibility of killifish (Orys.as latipes) to three pesticides with growth, Korean J. Environ. Asric. 6, 50-60
4 Lee, J. (1978) A Study on Degradation of Butachlor by a Soil Fungus, Chaetomium globosum, J. Korean Agric. Chem. 21, 1
5 European Communides (1984) OfBcial Joumal of the European Communities 27(L251)
6 Macek, K. J., Petrocelli, S. R. and Sleight, B. H. (1979) In Aquatic Toxicology: Considerations in Assessing the Potentialfor, and Sienificance of, Biomasnification of Chemicat Residues in Aquatic Food Chains, Marking, L. L., and Kimerle, R. A. (eds.), Proceeding of the 2nd Aim. Symp. on Aquadc Toxicology, ASTM, Philadelphia p.251-268
7 OECD (1981) OECD guidelines for Testing of Chemicals. Section 2: Effects on Biotic Systems, OECD Pans
8 European Communities (1979) OfBcial Joumal of the European Communities, 22(L251) p. 9-28
9 通商産業省 基礎産業局 化學品安全課(1985) 化審法開係
10 US EPA (1996) Ecological Effects Test Guidelines, OPPTS 850.1730, Fish BCF, EPA 712-C-96-129
11 Lyman, W. J., Reehl, W. F. and Rosenblatt, D. H. (1982) Handbook of chemical property estimation methods, Environmental Behavior of Organic Compounds, '5. Bioconcentration factor in aquatic organisms' McGraw-Hill, Inc
12 Takimoto, Y., Ohshtma, M., Yamada, H. and Miyamoto, J. (1984) Fate of Fenitrothion in Several Developmental Stages of the Killifish (Oryzias latipes), Arch. Erwiron. Contam. Toxicol.13, 579-587   DOI
13 Freitag, D., Geyer, H., Kraus, A., Viswanathan, R., Kotzias, D., Attar, A., Klein, W. and Korte, F. (1982) Ecotoxicological Profile Analysis: VII. Screening Chemicals for their Environmental Behavior by Comparative Evaluation, Ecotoxicology and Environmental Safety 6, 60-81   DOI   ScienceOn
14 OECD (1996) OECD guidelines for Testing of Chemica1s.,Section 3: Degradation and Accumulation,Bioconcentration: How-through Fish Test, 305(Adopted: 14.06.96), OECD Paris
15 Kenaga, E. E, and Goring, C. A. I. (1980) In AquaticToxicotogy: Relatwnship between Water Solubitity, Soil Sorption, Octanol-Water Partitioning, and Concentration of Chemicals in Biota, Eaton, J. G., Parrish, P. R. and Hendncks,H.C. (eds.), Proceedings of the 3rd Ann. Symp. on Aquatic Toxicology, ASTM, Philadelphia p. 78-115
16 Macek, K. J. and Petrocelli, S. R. (1979) In Test Pmtocols for Environmental Fate & Movement of Toxicants: Measuring thepotentil for and evaluating the significance of contamination of aquatic organisms by chemicat residues, Proceedings of a Symposium, AOAC 94th Annual Meeting AOAC. pp. 168-176
17 Agncultural Chemicals Industrial Associadon (1998) Agrochemical Year Book Seoul