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http://dx.doi.org/10.48022/mbl.2206.06010

Effect of Synbiotics-Added Feeds on the Growth, Non-Specific Immune Response, and Disease Resistance of Olive Flounders, Paralichthys olivaceus  

Chae-Yun Moon (Department of Aquatic Life Medicine, Jeju National University)
Hong-Ju Son (Department of Life Science and Environmental Biochemistry, Pusan National University)
Moon-Soo Heo (Department of Aquatic Life Medicine, Jeju National University)
Publication Information
Microbiology and Biotechnology Letters / v.50, no.3, 2022 , pp. 347-353 More about this Journal
Abstract
In this study, the effect of a synbiotic mixture of probiotics and 3% inulin on the growth, non-specific immune response, and mortality due to disease resistance of Paralichthys olivaceus was investigated. The results revealed that an 8-week diet of synbiotic-added feed, had no significant effect on the growth of P. olivaceus, Analysis of the hematological parameters revealed that there was a significant difference in the content of AST, total protein, and cholesterol among the groups, whereas there was no significant difference in the ALT and glucose contents. Further, there was no significant difference in the lysozyme activity of the synbiotic and control group after 8 weeks' feeding. In addition, when the symbiotic mixture was used rather than probiotics alone, the NBT activity of the synbiotic group increased compared to that of the control group. Moreover, when only probiotics were used, the cytokine expression in the spleen of the samples was significantly lower than that in the control group, whereas the expression was significantly higher in the spleen of the synbiotics group. However, there was no significant difference in the cytokine expression in the liver, intestine, and kidney of the three groups. Lastly, after injection for 2 weeks, the mortality rates of the control group towards Edwardsiella tarda, Streptococcus parauberis, and Streptococcus iniae were 95, 85 and 85%, respectively; those of the probiotics group were 85, 80, and 80%, respectively; and those of the synbiotics group were 80, 80, and 85%, respectively.
Keywords
Synbiotics; probiotics; prebiotics; Paralichthys olivaceus; non-specific immune; Bacillus cabrialesii;
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