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http://dx.doi.org/10.4014/mbl.1510.10002

Anti-Melanogenesis and Anti-Wrinkle Effects of Sargassum micracanthum Extracts  

Pak, Won-Min (Department of Food Science & Technology / Institute of Food Science, Pukyong National University)
Kim, Koth-Bong-Woo-Ri (Institute of Fishries Sciences, Pukyong National University)
Kim, Min-Ji (Department of Food Science & Technology / Institute of Food Science, Pukyong National University)
Park, Ji-Hye (Department of Food Science & Technology / Institute of Food Science, Pukyong National University)
Bae, Nan-Young (Department of Food Science & Technology / Institute of Food Science, Pukyong National University)
Park, Sun-Hee (Department of Food Science & Technology / Institute of Food Science, Pukyong National University)
Ahn, Dong-Hyun (Department of Food Science & Technology / Institute of Food Science, Pukyong National University)
Publication Information
Microbiology and Biotechnology Letters / v.44, no.1, 2016 , pp. 19-25 More about this Journal
Abstract
Sargassum micracanthum (SM) is a member of the family Sargassaceae and commonly occurs along the coast of Korea. Extracts from SM were evaluated for their antioxidant and collagenase and tyrosinase inhibitory activities based on their total phenolic concentration (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging effect, and metal-chelating effect. The TPC of SM ethanol and water extracts used in the study was 11.20 and 11.70 mg/g of dry sample, respectively. Both SM ethanol and water extracts had high DPPH radical-scavenging effect. The metal-chelating effect of SM ethanol extract (40.47% at 0.5 mg/ml) was higher than that of water extract (23.28% at 0.5 mg/ml). With regard to the anti-wrinkling effect, SM ethanol extract showed collagenase inhibitory activity with an $IC_{50}$ value of $488.20{\mu}g/ml$. Lastly, regarding the anti-melanogenesis effect, SM ethanol extract showed higher tyrosinase inhibitory activity (45.08% at 5 mg/ml) than that shown by the water extract (21.29% at 5 mg/ml). These results suggest that SM has the potential to be a resource with natural anti-melanogenesis, anti-wrinkle, and anti-oxidant effects.
Keywords
Sargassum micracanthum; antioxidant activity; tyrosinase inhibitory activity; collagenase inhibitory activity;
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