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http://dx.doi.org/10.7845/kjm.2014.4002

Antioxidant Activities and Monacolin K Production of Fermented Chinese Yam by Monascus sp. MK805  

Jeon, Chun-Pyo (Department of Medicine Quality Analysis, Andong Science College)
Publication Information
Korean Journal of Microbiology / v.50, no.1, 2014 , pp. 46-52 More about this Journal
Abstract
This study was carried out to investigate the characteristics of fermented chinese yam and rice (Dioscorea japonica, Dioscorea batatas, Dioscorea opposita, Rice, FCYR) using Monascus sp. MK805. The extracts from FCYR were measured to examine pigments, antioxidant activities were investigated through DPPH radical scavenging activity, total polyphenol and flavonoid contents, reducing power. Also it was investigated monacolin K productivity by FCYR. Pigments productivity (yellow, orange and red) were 26.2, 13.9, 17.3 at Dioscorea japonica, 41.9, 22.6, 53.2 at Dioscorea batatas, 12.5, 7.5, 9.7 at Dioscorea opposita and 10.1, 7.7, 10.2 at rice, respectively. DPPH radical scavenging activity of FCYR was about 69.7, 79.6, 57.8, and 42.3%, total polyphenol contents of FCYR was about 480.6, 658.7, 379.3, and 212.9 mg/kg, total flavonoid contents of FCYR was about 342.5, 448.4, 235.2, and 168.7 mg/kg, reducing power of FCYR was about 1.57, 2.14, 1.14, and 0.35 (OD at 700 nm), respectively. And then monacolin K productivity of FCYR was about 453.8, 509.5, 332.2, and 263.2 mg/kg, respectively.
Keywords
biological activities; fermented chinese yam; monacolin K;
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1 Jia, Z., Tang, M., and Wu, J. 1999. The determination of flavonoid contents in mulberry and they scavenging effects on superoxide radicals. Food Chem. 64, 555-559.   DOI   ScienceOn
2 Judie, D.D. 1987. Applications and colorants. Food Technol. 23, 78-88.
3 Hertog, M.G.L., Hollman, P.C.H., and Katan, M.B. 1992. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands. J. Agric. Food Chem. 40, 2379-2383.   DOI
4 Ferreres, F., Gomes, D., Valentao, P., Goncalves, R., Pio, R., Chagas, E.A., Seabra, R.M., and Andrade, P.B. 2009. Improved loquat (Eriobotrya japonica Lindl.) cultivars: Variation of phenolics and antioxidative potential. Food Chem. 114, 1019-1027.   DOI   ScienceOn
5 Gordon, M.H. 1990. The mechanism of antioxidant action in vitro, pp. 1-8. Food antioxidants. In Hudson, B.J.F. (ed.). Elsevier Applied Science, London, UK.
6 Ha, Y.D., Lee, S.P., and Kwak, Y.G. 1998. Removal of heavy metal and ACE inhibition of yam mucilage. Kor. J. Soc. Food Sci. Nutr. 27, 751-755.   과학기술학회마을
7 Hwang, J. and Hseu, T.H. 1980. Specificity of the acid protease from Monascus kaoliang toward the-B-chain of oxidized insulin. Biochem. Biophys. Acta 614, 607-612.
8 Ige, M.T. and Akintunde, F.O. 1981. Studies on the local techniques for yam flour production. J. Food Technol. 16, 303-311.
9 Jeon, C.P., Lee, J.B., Choi, C.S., and Kwon, G.S. 2011. Biological activities of ethanol extracts from monascus-fermented chinese yam. J. Life Sci. 21, 1142-1148.   과학기술학회마을   DOI   ScienceOn
10 Jeon, C.P., Lee, J.G., Lee, J.B., Park, S.C., Choi, C.S., Kim, J.E., and Kwon, G.S. 2012. Biological activities of fermented Dioscorea batatas Dence by two stage fermentation. Kor. J. Microbiol. 48, 29-36.   과학기술학회마을   DOI   ScienceOn
11 Ainsworth, G.C., Sparrowr, F.K., and Sassman, A.S. 1973. The fungi, p. 35. Academic press, New York, USA.
12 Tanaka, O. 1990. Recent studies on glycosides from plant drugs of himalaya and south western china: Chemogeographical correlation of panax species. Pure Appl. Chem. 62, 1281-1284.
13 Su, Y.C. 1975. Properties of Monascus anka and its utilization. J. Ferment. Assoc. 33, 28-34.
14 Swain, T., Hillis, W.E., and Oritega, M. 1959. Phenolic constituents of Prunus domestica. 1. Quantitative analysis of phenolic constituents. J. Sci. Food Agric. 10, 83-88.
15 Sweny, J.G., Estrada-Valdes, M.C., Iacobucci, G.A., Sato, H., and Sakamura, S. 1981. Photoprotection of the red pigments of Monascus anka in aqueous media by 1,4,6-trihydroxynaphthalene. J. Agric. Food Chem. 29, 1189-1193.   DOI
16 Wild, D., Tech, G., and Humpf, H.U. 2002. New Monascus metabolite isolated from red yeast rice (ang-kak, red koji). J. Agric. Food Chem. 50, 3999-4002.   DOI   ScienceOn
17 Chung, H.J. 1999. Antioxidative effect of ethanolic extracts of some tea materials on red pepper seed oil. Korean J. Soc. Food Sci. Nutr. 28, 1316-1320.   과학기술학회마을
18 Babitha, S., Soccol, C.R., and Pandey, A. 2007. Solid-state fermentation for the production of Monascus pigments from jackfruit seed. Bioresour. Technol. 98, 1554-1560.   DOI   ScienceOn
19 Blois, M.S. 1958. Antioxidant determinations by the use of a stable free radical. Nature 181, 1199-1200.   DOI   ScienceOn
20 Cha, J.Y., Ahn, H.Y., Eom, K.E., Park, B.K., Jun, B.S., and Cho, Y.S. 2009. Antioxidative activity of Aralia elata shoot and leaf extracts. J. Life Sci. 19, 652-658.   과학기술학회마을   DOI
21 Endo, A. 1979. Monacolin K, a new hypocholesterolemic agent produced by a Monascus species. J. Antibiot. 32, 852-854.   DOI
22 Kwon, C.S., Shon, H.Y., Kim, S.H., Kim, J.H., Son, G.H., Lee, J.S., Lim, J.K., and Kim, J.S. 2003. Anti-obesity effect of Dioscorea nipponica Makino with lipase-inhibitory activity in rodents. Biosci. Biotechnol. Biochem. 67, 1451-1456.   DOI   ScienceOn
23 Jung, D.H. 2007. Encyclopedia of Health and Functional Foods, pp. 191-192. Shinil Books Publishing Co., Seoul, Korea.
24 Kim, J.I., Jang, H.S., Kim, J.S., and Shon, H.Y. 2009. Evaluation of antimicrobial, antithrombin and antioxidant activity of Dioscorea batatas Dence. Kor. J. Microbiol. Biotechnol. 37, 133-139.   과학기술학회마을
25 Kim, H.K., Lee, B.Y., and Kim, Y.E. 1993. Development of functional new materials from some Korea plants (in Korea). Korea Food Reaearch Institute Report. E1218-0420.
26 Lin, C.F. 1973. Isolation and cultural conditions of Monascus sp. for the production of pigment in a submerged culture. J. Ferment. Technol. 51, 107-114.
27 Kwon, C.S., Son, I.S., Shim, H.Y., Kwon, I.S., and Chung, K.M. 1999. Effects of yam on lowering cholesterol level and its mechanism. Kor. J. Food Nutr. 32, 637-643.   과학기술학회마을
28 Lee, C.L., Wang, J.J., Kuo, S.L., and Pan, T.M. 2006. Monascus fermentation of dioscorea for increasing the production of cholesterol-lowering agent-monacolin K and antiinflammation agent-monascin. Appl. Microbiol. Biotechnol. 72, 1254-1262.   DOI   ScienceOn
29 Lee, Y.L., Yang, J.H., and Mau, J.L. 2008. Antioxidant properties of water extracts from Monascus fermented soybeans. Food Chem. 106, 1128-1137.   DOI   ScienceOn
30 Park, J.C., Cha, J.Y., Lee, C.H., Doh, E.S., Kang, I.H., and Cho, Y.S. 2009. Biological activities and chemical characteristics of Monascusfermented Korean red ginseng. J. Life Sci. 19, 1553-1561.   DOI
31 Purseglove, J.W. 1972. Dioscoreaceae, p. 97. Tropocal crops monocotyledons. In Longman, I. (ed.). London, UK.
32 Bilheimer, D.W., Grundy, S.M., Brown, M.S., and Goldstein, J.L. 1983. Mevinolin and colestipol stimulate receptor mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes. Proc. Natl. Acad. Sci. USA 80, 4124-4128.   DOI   ScienceOn
33 Asper, V. and Coursey, D.G. 1967. Properties of starches of some west african yams. J. Sci. Food Agric. 18, 240.   DOI