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http://dx.doi.org/10.5657/KFAS.2022.0310

Antioxidant and Physiological Activities of Different Solvent Extracts of Cnidium japonicum  

Kim, Ji-Youn (Department of Food Science and Biotechnology, Kunsan National University)
Lee, Yeon-Ji (Department of Food Science and Biotechnology, Kunsan National University)
Kim, Won-Suk (Department of Pharmaceutical Engineering, Silla University)
Moon, Soo-Kyung (Department of Food and Nutrition/Institute of Agriculture and Life Science, Gyeongsang National University)
Kim, Yong-Tae (Department of Food Science and Biotechnology, Kunsan National University)
Publication Information
Korean Journal of Fisheries and Aquatic Sciences / v.55, no.3, 2022 , pp. 310-318 More about this Journal
Abstract
Cnidium japonicum a biennial plant belonging to the family Umbelliferae, is a halophyte that grows in high-salinity areas of coastal sand dunes and sandy shores. This study was conducted to investigate the constituents, antioxidant activities, and physiological activities of C. japonicum. Mineral analyses revealed that potassium, sodium, calcium, and magnesium were the most prevalent minerals in C. japonicum. We used 80% ethanol, 80% methanol, and distilled water as solvents to prepare extracts from C. japonicum tissues, and the obtained extraction yields ranged between approximately 26% and 32%. Among the three extracts, the ethanol and methanol extracts had higher total polyphenol and flavonoid levels than the water extracts did. The antioxidant activities of methanol extracts were the highest among the various solvent extracts of C. japonicum as was the elastase/collagenase inhibitory activity. In contrast, the ethanol extract exhibited the highest tyrosinase inhibitory activity. Furthermore, the methanol extract possessed over 80% BACE1 (β-secretase) inhibitory activity at a final concentration of 20 ㎍/mL. Therefore, these results indicate that methanol and ethanol extracts of C. japonicum may be useful as antioxidant and functional substances in food and pharmaceutical material.
Keywords
Antioxidative activity; Cnidium japonicum; General component; Halophyte; Physiological activity;
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