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http://dx.doi.org/10.4163/jnh.2022.55.2.201

2020 Dietary Reference Intakes for Koreans: vitamin A  

Kim, Yuri (Department of Nutritional Science and Food Management, Ewha Womans University)
Publication Information
Journal of Nutrition and Health / v.55, no.2, 2022 , pp. 201-210 More about this Journal
Abstract
Vitamin A (Vit A) is a lipid-soluble vitamin required for diverse normal body functions, including good vision, reproduction, growth, development, and cellular differentiation. The therapeutic effects of Vit A have been demonstrated for the treatments of inflammation, low immunity, and cancer. The present review discusses the scientific evidence for establishing the 2020 Dietary Reference Intakes for Koreans (KDRI) for Vit A, issues caused by unit change of Vit A, and suggestions for the 2025 KDRI revision. Due to the changes in the standard bodyweight observed in several age groups, the 2020 KDRI had minor revisions as compared to the 2015 KDRI. In the 2015 KDRI, the Vit A unit has changed from retinol equivalent (RE) to retinol activity equivalent (RAE) and the activity of carotenoids became half with RAE compared to RE due to this unit change. Since the Vit A intake of Koreans relies heavily on plant-based carotenoids, the dietary intake of Vit A in Koreans as determined by considering the RAE was much lower than values obtained with RE. The analysis for Vit A intake by the Korean National Health and Nutrition Survey only reflects intakes of retinol and beta-carotene. Thus, it would be necessary to include the consumption of other provitamin A, such as alpha-carotene and beta-cryptoxanthin. Moreover, assessing the amounts of Vit A in foods should be customized to Korean diets since there are seasonal variations in the carotenoid concentration of plants. Moreover, other factors such as age- and sex-specific intake data and considerations of baseline micronutrient status, body mass index, and dietary patterns should be considered for developing more precise KDRI. In particular, the Vit A requirement needs to be met by consuming diverse foods, including animal foods.
Keywords
vitamin A; retinol; carotenoids; intake;
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1 American Board of Internal Medicine. ABIM laboratory test reference ranges - January 2022 [Internet]. Philadelphia (PA): American Board of Internal Medicine; 2022 [cited 2022 Jan 21]. Available from: https://www.abim.org/Media/bfijryql/laboratory-reference-ranges.pdf.
2 Shim JE, Paik HY, Lee SY, Moon HK, Kim YO, Kwon HH, et al. Assessment of vitamin A and E status in Korean rural adult population by dietary intake and serum levels. Korean J Nutr 2001; 34(2): 213-221.
3 Ministry of Health and Welfare (KR); The Korean Nutrition Society. Dietary Reference Intakes for Koreans 2020. Sejong: Ministry of Health and Welfare; 2020.
4 U.S. Department of Agriculture, Agricultural Research Service. FoodData Central [Internet]. Washington, D.C.: U.S. Department of Agriculture, Agricultural Research Service; 2019 [cited 2022 Jan 21]. Available from: https://fdc.nal.usda.gov/index.html.
5 Ross AC, Moran NE. Our current dietary reference intakes for vitamin A-Now 20 years old. Curr Dev Nutr 2020; 4(10): nzaa096.   DOI
6 Merck Sharp & Dohme Corp. MSD manual professional version [Internet]. Kenilworth (NJ): Merck Sharp & Dohme Corp.; [cited 2022 Jan 21]. Available from: https://www.msdmanuals.com/professiona.
7 Smith JC Jr. The vitamin A-zinc connection: a review. Ann N Y Acad Sci 1980; 355: 62-75.   DOI
8 Yee MM, Chin KY, Ima-Nirwana S, Wong SK. Vitamin A and bone health: a review on current evidence. Molecules 2021; 26(6): 1757.   DOI
9 Palace VP, Khaper N, Qin Q, Singal PK. Antioxidant potentials of vitamin A and carotenoids and their relevance to heart disease. Free Radic Biol Med 1999; 26(5-6): 746-761.   DOI
10 Harris L, Abbasy M. The dark-adaptation test: its reliability as a test for vitamin A deficiency. Lancet 1939; 234(6069): 1299-1359.   DOI
11 Tanumihardjo SA, Russell RM, Stephensen CB, Gannon BM, Craft NE, Haskell MJ, et al. Biomarkers of Nutrition for Development (BOND)-Vitamin A review. J Nutr 2016; 146(9): 1816S-1848S.   DOI
12 Kim Y. Recommended intake and dietary intake of vitamin A for Koreans by unit of retinol activity equivalent. Korean J Community Nutr 2016; 21(4): 344-353.   DOI
13 Niranjana R, Gayathri R, Nimish Mol S, Sugawara T, Hirata T, Miyashita K, et al. Carotenoids modulate the hallmarks of cancer cells. J Funct Foods 2015; 18: 968-985.   DOI
14 Wei J, Ji JS. Association of serum vitamins with eczema in US adults (NHANES 2005-2006). Dermatology 2020; 236(2): 179-182.   DOI
15 Tanumihardjo SA, Vitamin A. Vitamin A: biomarkers of nutrition for development. Am J Clin Nutr 2011; 94(2): 658S-665S.
16 Solomons NW, Morrow FD, Vasquez A, Bulux J, Guerrero AM, Russell RM. Test-retest reproducibility of the relative dose response for vitamin A status in Guatemalan adults: issues of diagnostic sensitivity. J Nutr 1990; 120(7): 738-744.   DOI
17 Stephensen CB. Vitamin A, infection, and immune function. Annu Rev Nutr 2001; 21(1): 167-192.   DOI
18 Edem DO. Vitamin A: a review. Asian J Clin Nutr 2009; 1(1): 65-82.   DOI
19 Sauberlich HE, Hodges RE, Wallace DL, Kolder H, Canham JE, Hood J, et al. Vitamin A metabolism and requirements in the human studied with the use of labeled retinol. Vitam Horm 1974; 32: 251-275.
20 Rucker RB, Zempleni J, Suttie JW, McCormick DB. Vitamin A: nutritional aspects of retinoids and carotenoids. In: Handbook of Vitamins. Boca Raton (FL): CRC Press; 2007. p. 2-3.
21 Khasru MR, Yasmin R, Salek AK, Khan KH, Nath SD, Selim S. Acute hypervitaminosis A in a young lady. Mymensingh Med J 2010; 19(2): 294-298.
22 Melse-Boonstra A, Vossenaar M, van Loo-Bouwman CA, Kraemer K, de Pee S, West KP Jr, et al. Dietary vitamin A intake recommendations revisited: global confusion requires alignment of the units of conversion and expression. Public Health Nutr 2017; 20(11): 1903-1906.   DOI
23 Du W, Wang H, Wang Z, Zhang J, Su C, Jia X, et al. Dietary vitamin a intake among Chinese adults: findings from CNTCS2015. Nutr J 2018; 17(1): 60.   DOI
24 Matsuda-Inoguchi N, Date C, Sakurai K, Kuwazoe M, Watanabe T, Toji C, et al. Reduction in estimated vitamin A intake induced by new food composition tables in Japan, where vitamin A is taken mostly from plant foods. Int J Food Sci Nutr 2006; 57(5-6): 279-291.   DOI
25 West KP Jr. Vitamin A deficiency disorders in children and women. Food Nutr Bull 2003; 24(4 Suppl): S78-S90.   DOI
26 Tafti M, Ghyselinck NB. Functional implication of the vitamin A signaling pathway in the brain. Arch Neurol 2007; 64(12): 1706-1711.   DOI
27 Doldo E, Costanza G, Agostinelli S, Tarquini C, Ferlosio A, Arcuri G, et al. Vitamin A, cancer treatment and prevention: the new role of cellular retinol binding proteins. BioMed Res Int 2015; 2015: 624627.   DOI
28 Palmer AC, West KP Jr, Dalmiya N, Schultink W. The use and interpretation of serum retinol distributions in evaluating the public health impact of vitamin A programmes. Public Health Nutr 2012; 15(7): 1201-1215.   DOI
29 Weber D, Grune T. The contribution of β-carotene to vitamin A supply of humans. Mol Nutr Food Res 2012; 56(2): 251-258.   DOI
30 Kim SA, Jun S, Joung H. Estimated dietary intake of vitamin A in Korean adults: based on the Korea National Health and Nutrition Examination Survey 2007~2012. J Nutr Health 2016; 49(4): 258-268.   DOI
31 Noh HH, Kim YN, Cho YO. Intakes and major food sources of vitamins A and E of Korean adults living in Seoul and Gyeonggi province. Korean J Nutr 2010; 43(6): 628-637.   DOI
32 Hyun WJ, Lee JW. Seasonal and regional variations in nutrient intakes of Korean adolescents as assessed as 3-day dietary records. Korean J Community Nutr 2001; 6(4): 592-603.
33 Kim K, Choi J, Pak SB. Association between vitamin A, E and type 2 diabetes mellitus in Korea: Korean National Health and Nutrition Examination Survey 2016-2018. Korean J Fam Pract 2021; 11(2): 135-141.   DOI
34 Hong KH, Lee Y. Negative correlation between vitamin A and positive correlation between vitamin E and inflammation among healthy adults in Korea: based on the Korea National Health and Nutrition Examination Survey (KNHANES) 2016-2018 7th Edition. J Inflamm Res 2020; 13: 799-811.   DOI
35 Rural Development Administration (KR). Korean Food Composition Table. 9th Revision. Wanju: Rural Development Administration; 2016.
36 Gilbert C. The eye signs of vitamin A deficiency. Community Eye Health 2013; 26(84): 66-67.
37 Institute of Medicine (US). Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press; 2001.