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http://dx.doi.org/10.4163/jnh.2013.46.6.493

Effect of fermented soybean curd residue (FSCR; SCR-meju) by aspergillus oryzae on the anti-obesity and lipids improvement  

Lee, Sang-Il (Department of Food, Nutrition and Culinary Arts, Keimyung College)
Lee, Ye-Kyung (Center for Nutraceutical and Pharmaceutical Materials, Myongji University)
Kim, Soon-Dong (Center for Nutraceutical and Pharmaceutical Materials, Myongji University)
Lee, Ji-Ean (Center for Nutraceutical and Pharmaceutical Materials, Myongji University)
Choi, Jongkeu (Department of Cosmetic Science, Chungwoon University)
Bak, Jong-Phil (Center for Nutraceutical and Pharmaceutical Materials, Myongji University)
Lim, Jong-Hwan (Center for Nutraceutical and Pharmaceutical Materials, Myongji University)
Suh, Joo-Won (Center for Nutraceutical and Pharmaceutical Materials, Myongji University)
Lee, In-Ae (Center for Nutraceutical and Pharmaceutical Materials, Myongji University)
Publication Information
Journal of Nutrition and Health / v.46, no.6, 2013 , pp. 493-502 More about this Journal
Abstract
In this study, we designed to confirm the dietary effect of anti-obesity of fermented soybean curd residue (FSCR; SCR-Meju; Biji-meju) by A. oryzae, which is well known as a Korean traditional meju microbe. We observed that body weight gain, serum and hepatic lipid profile, as well as the activity of ROS generating enzyme and ROS scavenging enzyme in high-fat diet induced obese mice fed experimental diet (SCR and SCR-meju). Body weight gain and epididymal fat weight of HC (high-fat diet control) was markedly higher than that of NC (Normal control). Conversely, body weight gain and epididymal fat weight of the SCR (Biji) and SCR-meju (Biji-meju) group was significantly lower than that of HC; these of the SCR-meju group was lower than that of the SCR group. Furthermore, serum TG and total-cholesterol and LDL-cholesterol contents of SCR and SCR-meju groups were lower than that of HC, and HDL-cholesterol level of the SCR-meju group was significantly higher than that of HC. In conclusion, although precise mechanisms of the antiobese effects of SCR-meju in this study are unknown, the present study provides an experimental evidence that SCR-meju may prevent obesity and obesity related metabolic syndromes, such as hyperlipidemia, hypertension and diabetes, and liver disease by high-fat diet. Nevertheless, further study in this filed will be needed.
Keywords
soybean curd residue (SCR, biji); aspergillus oryzae; SCR-meju (biji-meju); anit-obesity; antioxidant enzymes;
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