Browse > Article
http://dx.doi.org/10.4163/kjn.2012.45.5.452

Increased whole grain, fruits and vegetable intake reduced oxidative stress in high school students  

Kim, So Hyeon (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University)
Cho, Sang Woon (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University)
Hwang, Seong Su (Deagu Medical Center)
Ahn, Mijung (Department of Nutrition, Deagu Medical Center)
Lee, Dukhee (Department of Preventive Medicine and Health Promotion Research Center, School of Medicine, Kyungpook National University)
Kang, Seung Wan (Institute of Complementary and Integrative Medicine, Seoul National University Medical Research Center)
Park, Yoo Kyoung (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University)
Publication Information
Journal of Nutrition and Health / v.45, no.5, 2012 , pp. 452-461 More about this Journal
Abstract
There is increasing evidence that dietary factors in plant-based diets are important for the prevention of chronic disease. Especially, phytonutrients in fruits and vegetables have been recognized as major contributors for the decreased level of oxidative stress. In this study, the effect of switching the dietary habit to high consumption of fruits and vegetables were evaluated on the parameters of serum antioxidant status in healthy high school students. Forty one students participated in a randomized controlled trial and were assigned to the control group (n = 18) or the intervention group (n = 23). The intervention group was provided for 8 weeks with the main food source being whole grain and vegetables. Anthropometric measurements, blood parameters and dietary intakes were measured, and compared before and after study. After 8 weeks, weight and BMI were significantly decreased in the intervention group (p = 0.000). The serum diacron reactive oxygen metabolites (d-ROMs) test resulted in a significantly decreased level only in the intervention group (p < 0.05) after 8 weeks, but serum biological antioxidant potential (BAP) was increased significantly in both groups (p < 0.001). Intake of energy, total fat, cholesterol and sodium in the intervention group were significantly decreased after 8 weeks (p < 0.05). Also, the intervention group had significantly increased vitamin and phytonutrient intakes of all-trans-${\beta}$-carotene, ${\alpha}$-carotene, ${\alpha}$-tocopherol, ascorbic acid, and total phenols (p < 0.05). Overall, the results of this study suggest that whole grain, fruits, and vegetables supplementation showed improvement of the adolescent health.
Keywords
phytochemical-rich diet; antioxidant status; intervention; adolescent health;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
연도 인용수 순위
1 Palmieri B, Sblendorio V. Oxidative stress tests: overview on reliability and use. Part II. Eur Rev Med Pharmacol Sci 2007; 11(6): 383-399
2 Trotti R, Carratelli M, Barbieri M, Micieli G, Bosone D, Rondanelli M, Bo P. Oxidative stress and a thrombophilic condition in alcoholics without severe liver disease. Haematologica 2001; 86 (1): 85-91
3 Yim KS, Lee TY, Park HS. The development and validation of a food frequency questionnaire to assess diets of Korean adolescents. Korean J Community Nutr 2003; 8(2): 149-159
4 Cho YS. Evaluation of phytonutrients and antioxidant activities of Korean vegetables, fruits and legumes [dissertation]. Seoul: Yonsei University; 2006
5 Ministry of Health and Welfare, The Korea Institute for Health and Social Affairs. The third national health promotion plan (2011-2020) in Korea. Seoul: The Korea Institute for Health and Social Affairs; 2011
6 Paek KW. Dietary pattern analysis and factors affecting abdominal obesity in children and adolescents. J Korean Soc Sch Health 2009; 22(2): 137-146
7 Kim GR, Kim MJ. A survey on the dietary behavior of high school students - about regularity of meal and number of meal per day. J Korean Soc Food Sci Nutr 2011; 40(2): 183-195   DOI
8 Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. The third Korea National Health and Nutrition Examination Survey (KNH-ANES IV). Cheongwon: Korea Centers for Disease Control and Prevention; 2008
9 Cho HS, Kim MH, Choi MK. A study on vegetable intakes and dietary habits of middle school students in Chungnam. Korean J Community Nutr 2010; 15(4): 525-535
10 Choi MK. A study on the relationship between fast food consumption patterns and nutrition knowledge, dietary attitude of middle and high school students in Busan. Korean J Culinary Res 2007; 13(2): 188-200
11 Johnson F, Wardle J, Griffith J. The adolescent food habits checklist: reliability and validity of a measure of healthy eating behaviour in adolescents. Eur J Clin Nutr 2002; 56(7): 644-649   DOI   ScienceOn
12 American Dietetic Association; Dietitians of Canada. Position of the American Dietetic Association and Dietitians of Canada: vegetarian diets. Can J Diet Pract Res 2003; 64(2): 62-81   DOI   ScienceOn
13 Buchner FL, Bueno-de-Mesquita HB, Ros MM, Overvad K, Dahm CC, Hansen L, Tjonneland A, Clavel-Chapelon F, Boutron-Ruault MC, Touillaud M, Kaaks R, Rohrmann S, Boeing H, Nothlings U, Trichopoulou A, Zylis D, Dilis V, Palli D, Sieri S, Vineis P, Tumino R, Panico S, Peeters PH, van Gils CH, Lund E, Gram IT, Braaten T, Sanchez MJ, Agudo A, Larranaga N, Ardanaz E, Navarro C, Arguelles MV, Manjer J, Wirfalt E, Hallmans G, Rasmuson T, Key TJ, Khaw KT, Wareham N, Slimani N, Vergnaud AC, Xun WW, Kiemeney LA, Riboli E. Variety in fruit and vegetable consumption and the risk of lung cancer in the European prospective investigation into cancer and nutrition. Cancer Epidemiol Biomarkers Prev 2010; 19(9): 2278-2286   DOI
14 Park HJ, Lim SJ. Frequency of irritable bowel syndrome, perceived stress, and mental health among women. J Korean Acad Adult Nurs 2008; 20(5): 685-696
15 Research Institute of Food and Nutritional Sciences, Yonsei University. Phytonutrient contents in vegetable/fruits/legumes. Seoul: Shinkwang; 2009
16 Cho JH, Kim MK, Kim SH, Cho SW, Park YK. Association between hair mineral content and nutritional status in vegetarians and non-vegetarians. Korean J Nutr 2011; 44(3): 203-211   DOI
17 Barnard ND, Scialli AR, Turner-McGrievy G, Lanou AJ, Glass J. The effects of a low-fat, plant-based dietary intervention on body weight, metabolism, and insulin sensitivity. Am J Med 2005; 118 (9): 991-997   DOI   ScienceOn
18 Hebbelinck M, Clarys P, De Malsche A. Growth, development, and physical fitness of Flemish vegetarian children, adolescents, and young adults. Am J Clin Nutr 1999; 70(3 Suppl): 579S-585S
19 Larsson CL, Johansson GK. Young Swedish vegans have different sources of nutrients than young omnivores. J Am Diet Assoc 2005; 105(9): 1438-1441   DOI   ScienceOn
20 Hunt JR. Bioavailability of iron, zinc, and other trace minerals from vegetarian diets. Am J Clin Nutr 2003; 78(3 Suppl): 633S-639S
21 Davey GK, Spencer EA, Appleby PN, Allen NE, Knox KH, Key TJ. EPIC-Oxford: lifestyle characteristics and nutrient intakes in a cohort of 33 883 meat-eaters and 31 546 non meat-eaters in the UK. Public Health Nutr 2003; 6(3): 259-269
22 Tylavsky FA, Spence LA, Harkness L. The importance of calcium, potassium, and acid-base homeostasis in bone health and osteoporosis prevention. J Nutr 2008; 138(1): 164S-165S
23 Cornelli U, Terranova R, Luca S, Cornelli M, Alberti A. Bioavailability and antioxidant activity of some food supplements in men and women using the D-Roms test as a marker of oxidative stress. J Nutr 2001; 131(12): 3208-3211
24 Lubrano V, Vassalle C, L'Abbate A, Zucchelli GC. A new method to evaluate oxidative stress in humans. IBS 2002; 17(3): 172-175
25 Kakita H, Hussein MH, Daoud GA, Kato T, Murai H, Sugiura T, Mizuno K, Yamada Y, Ito T, Fukuda S, Kato I, Suzuki S, Togari H. Total hydroperoxide and biological antioxidant potentials in a neonatal sepsis model. Pediatr Res 2006; 60(6): 675-679   DOI   ScienceOn
26 Byun S, Kim JY, Cho SH, Kim JW, Hwang WW. The relationship between stress response and oxidative stress among healthy volunteers. Korean J Orient Prev Med 2009; 13(2): 27-38
27 Vassalle C, Novembrino C, Maffei S, Sciarrino R, De Giuseppe R, Vigna L, de Liso F, Mercuri A, Bamonti F. Determinants of oxidative stress related to gender: relevance of age and smoking habit. Clin Chem Lab Med 2011; 49(9): 1509-1513
28 Ishii T, Ohtake T, Okamoto K, Mochida Y, Ishioka K, Oka M, Maesato K, Ikee R, Moriya H, Hidaka S, Doi K, Noiri E, Fujita T, Kobayashi S. Serum biological antioxidant potential predicts the prognosis of hemodialysis patients. Nephron Clin Pract 2011; 117(3): c230-c236   DOI   ScienceOn
29 Ferdowsian HR, Barnard ND. Effects of plant-based diets on plasma lipids. Am J Cardiol 2009; 104(7): 947-956   DOI   ScienceOn
30 Holt EM, Steffen LM, Moran A, Basu S, Steinberger J, Ross JA, Hong CP, Sinaiko AR. Fruit and vegetable consumption and its relation to markers of inflammation and oxidative stress in adolescents. J Am Diet Assoc 2009; 109(3): 414-421   DOI   ScienceOn
31 Kim JS, Kim HY, Park YK, Kim TS, Kang MH. The effects of green vegetable juice (Angelica keiskei) supplementation on plasma lipids and antioxidant status in smokers. Korean J Nutr 2003; 36(9): 933-941
32 Kang JY, Kim SY, Lee MS, Ahn HS. Effect of vegetable juice supplementation on serum lipid profile and antioxidant activity in college women. Korean J Community Nutr 2005; 10(2): 183-188
33 Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A, Keogh JP, Meyskens FL, Valanis B, Williams JH, Barnhart S, Hammar S. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med 1996; 334(18): 1150-1155   DOI   ScienceOn
34 Liu S, Lee IM, Ajani U, Cole SR, Buring JE, Manson JE; Physicians' Health Study. Intake of vegetables rich in carotenoids and risk of coronary heart disease in men: The Physicians' Health Study. Int J Epidemiol 2001; 30(1): 130-135   DOI   ScienceOn
35 Buijsse B, Feskens EJ, Moschandreas J, Jansen EH, Jacobs DR Jr, Kafatos A, Kok FJ, Kromhout D. Oxidative stress, and iron and antioxidant status in elderly men: differences between the Mediterranean south (Crete) and northern Europe (Zutphen). Eur J Cardiovasc Prev Rehabil 2007; 14(4): 495-500   DOI   ScienceOn
36 Albanes D, Heinonen OP, Taylor PR, Virtamo J, Edwards BK, Rautalahti M, Hartman AM, Palmgren J, Freedman LS, Haapakoski J, Barrett MJ, Pietinen P, Malila N, Tala E, Liippo K, Salomaa ER, Tangrea JA, Teppo L, Askin FB, Taskinen E, Erozan Y, Greenwald P, Huttunen JK. Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta- carotene cancer prevention study: effects of base-line characteristics and study compliance. J Natl Cancer Inst 1996; 88(21): 1560-1570   DOI   ScienceOn
37 Duthie SJ, Jenkinson AM, Crozier A, Mullen W, Pirie L, Kyle J, Yap LS, Christen P, Duthie GG. The effects of cranberry juice consumption on antioxidant status and biomarkers relating to heart disease and cancer in healthy human volunteers. Eur J Nutr 2006; 45(2): 113-122   DOI   ScienceOn
38 Basu A, Imrhan V. Tomatoes versus lycopene in oxidative stress and carcinogenesis: conclusions from clinical trials. Eur J Clin Nutr 2007; 61(3): 295-303   DOI   ScienceOn