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Improve Effects of Saengshik on Patient with Fatty Liver and Hyperlipidemia in Murine  

송미경 ((주)이롬라이프 생명과학연구원)
홍성길 ((주)이롬라이프 생명과학연구원)
황성주 ((주)이롬라이프 생명과학연구원)
박옥진 (한남대학교 식품영양학과)
박미현 ((주)이롬라이프 생명과학연구원)
Publication Information
Journal of Nutrition and Health / v.36, no.8, 2003 , pp. 834-840 More about this Journal
Abstract
To examine the effect of Saengshik on parameters related to hepatoprotective, anthropometric, blood pressure, serum lipid and blood related indices, nonalcoholic fatty liver subjects were treated with two meal portion of Saengshik in the replacement of meals for a period of three months. Weight, Body Mass Index (BMI) and systolic blood pressure were significantly decreased after the treatment. Chronically elevated serum aspartate aminotransferase (AST), gamma-Glutamyl transferase (r-GTP) and Alkaline Phosphatase (ALP) levels showed reduction to the near normal range. Serum total triglyceride level were reduced following the treatment. Whereas, there were no changes of serum total cholesterol with Saengshik consumption. Also, additional study was conducted to investigate the effect of Saengshik supplementation to high cholesterol and fat diet on lipid metabolism in rats. Male Spraque-Dawley rats were administrated hyperlipidemiainducing diet containing 1% cholesterol and 10% lard to induce hyperlipidemia for 4 weeks and were fed on diet containing Saengshik (30%, w/w) for 7 weeks. The feeding of diet containing 30% Shaengshik significantly decreased total cholesterol (TC) contents and total triglyceride. These results demonstrate Saengshik may be beneficial for fatty liver patients in improving their lipid metabolism.
Keywords
uncooked natural food; fatty liver; hyperlipidemia; cholesterol;
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Times Cited By KSCI : 1  (Citation Analysis)
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