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The Effects of Chromium Picolinate Supplementation on Glucose and Lipid Level in Rats Fed in High Fat Diet  

오유진 (한양대학교 식품영양학과)
장유경 (한양대학교 식품영양학과)
Publication Information
Journal of Nutrition and Health / v.35, no.8, 2002 , pp. 834-839 More about this Journal
Abstract
This study aimed to investigate the effects of chromium picolinatec (CrP) supplementation on the glucose and lipid metabolism of rats. Five-week-old male Sprague-Dawley rats were fed a high-fat diet fir 110 days and further treated with CrP or placebos for 6 weeks. The effect of CrP supplementation on body weight, blood glucose, insulin and lipid levels was examined. The results suggested that body weight gain was not significantly different between the control and the CrP supplemented group. Plasma glucose, triglyceride and cholesterol levels in the CrP treated group significantly decreased compared to those of the control group (p < 0.05). The total lipid, triglyceride and cholesterol concentrations in the livers of the CrP treated group significantly decreased compared to those of the control group (p < 0.05). These results indicate that supplementation of chromium picolinate ran reduce triglyceride and glucose concentrations in the blood and total lipid and total cholesterol levels in the liver.
Keywords
chromium picolinate; high fat; blood cholesterol; glucose;
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Times Cited By KSCI : 4  (Citation Analysis)
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