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The Effects of Chromium Picolinate Supplementation on Glucose and Lipid Level in Rats Fed in High Fat Diet  

오유진 (한양대학교 식품영양학과)
장유경 (한양대학교 식품영양학과)
Publication Information
Journal of Nutrition and Health / v.35, no.8, 2002 , pp. 834-839 More about this Journal
Abstract
This study aimed to investigate the effects of chromium picolinatec (CrP) supplementation on the glucose and lipid metabolism of rats. Five-week-old male Sprague-Dawley rats were fed a high-fat diet fir 110 days and further treated with CrP or placebos for 6 weeks. The effect of CrP supplementation on body weight, blood glucose, insulin and lipid levels was examined. The results suggested that body weight gain was not significantly different between the control and the CrP supplemented group. Plasma glucose, triglyceride and cholesterol levels in the CrP treated group significantly decreased compared to those of the control group (p < 0.05). The total lipid, triglyceride and cholesterol concentrations in the livers of the CrP treated group significantly decreased compared to those of the control group (p < 0.05). These results indicate that supplementation of chromium picolinate ran reduce triglyceride and glucose concentrations in the blood and total lipid and total cholesterol levels in the liver.
Keywords
chromium picolinate; high fat; blood cholesterol; glucose;
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Times Cited By KSCI : 4  (Citation Analysis)
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1 A study of dietary patterns and nutrient intake in women with hypercholesterolemia /
[ Lee SL;Kim SY;Chang YK ] / Korean J Community Nutrition   과학기술학회마을
2 /
[] / Nutrition 21 Reports that Harvard Study Suggests Link between Low Chromium Levels and Increased Risk of Coronary Heart Disease
3 /
[ Han IK ] / Animal Nutrition for Animal
4 A simple methods for the isolation and purification of togal lipids from animal tissues /
[ Folch J;Lee M;Stanley GHS ] / J Biol Chem
5 Efficacy of chromium picolinate on performance and tissue accretion in pigs with different lean gain potential /
[ Mooney KW;Cromwell GL ] / J Anim Sci   DOI
6 /
[ National statistical office Republic of Korea ] / Annual report on the cause of death statistics
7 Serum cholesterol and glucose levels in rats fed refined and less refined sugars and chromium /
[ Schreoder HA ] / J Nutr   DOI
8 Dietary chromium tripicolinate supplementation reduces glucose concentrations and improves glucose tolerance in normal-weight cats /
[ Appleton DJ;Rand JS;Sunvold GD;Priest J ] / J Feline Medicine and Surgery   DOI   ScienceOn
9 Pathogenesis of Type 2 Diabetes in Korea Pathogenesis of Type 2 Diabetes in Korea /
[ Yoon KH ] / The Korean Diabetes As-sociation
10 Chromium as supplement /
[ Lukaski HC ] / Annu Rev Nutr
11 Performance, serum characteristics, carcase traits and lipid metabolism of broilers as affected by supplement of chromium picolinate /
[ Lien TF;Horng YM;Yang KH ] / Br Poult Sci   DOI   ScienceOn
12 /
[ Ekhard E;Zieger LJ;Filer Jr ] / Chromium in Present Knowledge in Nutrtion 7th
13 Quest for the molecular mechanism of chromium action and it's relationship to diabetes /
[ John BV ] / Nutrition Reviews   DOI   ScienceOn
14 Effects of streptozotocin-induced diabetes on insulin binding, glucose transport and intracellular glucose metabolism in isolated rat adipocytes /
[ Kobayashi M;Olefsky JM ] / Diabetes
15 /
[] / The 42nd Annual Conference on Cardiovascular Disease and Epidemiology Prevention
16 Chromium deficiency in rats: A syndrome simulating diabetes mellitus with retarded growth /
[ Schroeder HA ] / J Nutr   DOI
17 The effects of chromium picolinate supplementation on rats fed in high suvrose and high fat diets /
[ Oh YJ;Jin YC;Chang YK ] / J of Korean living Science Research
18 Chromium (Ⅲ) and the glucose tolerance factor /
[ Schwarz K;Mertz W ] / Arch Biochem Biophys   DOI   ScienceOn
19 /
[ Ministry of health and welfare ] / National nutrition survey report
20 Effects of chromium picolinate (CrP) on growth performance, carcass characteristics, and serum traits in growing-finishing pigs /
[ Min JK;Kim WY;Chae BJ ] / Asian Aust J Anim Sci   DOI
21 Reassessing the effects of simple carbohydrates on the serum triglyceride responses to fat meal /
[ Cohen JC;Schall R ] / Am J Clin Nutr   DOI
22 The effect of Cordyceps Militaris on lipids metabolism, protein levels and enzyme activities in rats fed a high fat diet /
[ Koh JB ] / Korean J Nutr   과학기술학회마을
23 /
[ Harper HA;Rodwell VW;Mayers PA ] / Review of Physiological Chemistry(17th)
24 /
[ WHO. Thec. Rep. Ser.;Hamilton, E.L.;Miniski M.J.;Cleary J ] / J. Sci Toxic Env
25 Effects of chromium picolinate supplementation on insulin sensitivity, serum lipids, and body weight in Dexamethasone-treated rats /
[ Kim DS;Kim TW;Park IK;Kang JS;Om AS ] / Metabolism   DOI   ScienceOn
26 Effect of Age on Lipid Metabolism in Rats Fed Diets with Different Fat Level and in Meal Fed Rats /
[ Jung HY;Lee KJ;Lee JS;Kim WY;Kim SH ] / Korean J Nutr   과학기술학회마을
27 Effect of chromium picolinate and chromium propionate on glucose and insulin kinetics of growing barrows and on growth and carcass traits of growing-finishing barrows /
[ Matthews JO;Southern LL;Ferandez JM;Pontif JE;Bidner TD;Odgaard RL ] / J Anim Sci   DOI
28 Influence of chromium picolinate on glucose usage and metabolic criteria in growing Holstein calves /
[ Bunting LD;Fernandez JM;Thompson DL Jr;Southern LL ] / J Anim Sci   DOI
29 Chromium intake, absorption and excretion of subjects consuming self-selected diets /
[ Anderson RA;Kozlovsky AS ] / Am J Clin Nutr   DOI
30 The case for supplemental chromium and a survey of clinical studies with chromium picolinate /
[ McCarty MF ] / J Appl Nutr
31 Does Chromium have a future in feed /
[ Jacques K;Stewart S ] / Feed Manag
32 Effect of chromium administration on glucose tolerance in stroke-prone spontaneously hypertensive rats with streptozotocin-induced diabetes /
[ Yoshimoto S;Sakamoto K;Wakabayashi I;Masui H ] / Metabolism   DOI   ScienceOn
33 Influence of supplemental chromium on concentrations of liver triglyceride, blood metabolites and rumen VFA profile in steers fed a moderately high fat diet /
[ Besong S;Jackson JA;Trammell DS;Akay V ] / J Dairy Sci   DOI   ScienceOn
34 /
[ FDA ] / Toxicity of the Essential Minerals
35 Normal Values of Serum Lipids in Healthy Adults by Sex and Age-With Particular Referece to Frquency of Dyslipidemia /
[ Gweon S;Koo SM;Cho BK;Jeong GH;Lee CK;Cheong ER;Ryu JK;Lee BR;Chae SC;Jun JE;Park WH;Bae KS ] / Korean J Medicine
36 Chromium occurrence and function in biological system /
[ Mertz W ] / Physiol Rev
37 A Comparison of the Methodologies in Food Consumption Surveys and Daily Dietary Fat Intake between America and Korea /
[ Park SM ] / Korean J Nutr   과학기술학회마을
38 Effect of obesity and insulin on immunity in non-insulin-dependent diabetes mellitus /
[ Mito N;Hiyoshi T;Hosoda T;Kitada C;Sato K ] / Eur J Clin Nutr   DOI   ScienceOn