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http://dx.doi.org/10.9799/ksfan.2016.29.5.595

Relation between Serum Uric Acid Levels and Metabolic Syndrome Markers among Koreans by Gender  

Park, Hyunjin (ICAN Nutrition Education and Research)
Ryu, Hyesook (Dept. of Food and Nutrition, Sangji University)
Jho, Kwanghyun (Dept. of Business Administration, Sahmyook University)
Ko, Jaeyoung (National Health Insurance Corporation Ilsan Haspital)
Yun, Mieun (Dept. of Food and Nutrition, Sahmyook University)
Publication Information
The Korean Journal of Food And Nutrition / v.29, no.5, 2016 , pp. 595-604 More about this Journal
Abstract
It has been reported that the increased uric acid level is associated with metabolic syndrome risk factors in both male and female. However, there has not been enough studies to investigate gender differences of this association in Korea. To evaluate relation between serum uric acids and metabolic syndrome markers, anthropometric and biochemical analyses data was obtained from National Health Examination 2005 and 5,523 (M=3,097; F=2,426) data was analyzed. Results by quartile of serum uric acid levels in females showed that increased serum uric acid level was associated with elevated levels of total-. LDL-cholesterol, and triglycerides, whereas association between serum uric acid and total cholesterol levels was not observed in male subjects. In both female and male, higher quartile of serum uric acid level were linked with lower levels of HDL-cholesterol. In regression analysis, association of serum uric acid levels with fasting glucose levels was significant in female subjects only. In conclusion, higher serum uric acid levels were associated with metabolic syndrome indices, however gender differences were existed for total cholesterol.
Keywords
serum uric acid; hyperuricemia; metabolic syndrome; gender differences;
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