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http://dx.doi.org/10.9799/ksfan.2012.25.2.233

The Effect of Portulaca oleracea on the Pathogens of Gastroenteritis in Infants  

Bae, Ji-Hyun (Dept. of Food Science and Nutrition, Keimyung University)
Publication Information
The Korean Journal of Food And Nutrition / v.25, no.2, 2012 , pp. 233-238 More about this Journal
Abstract
Diarrheal diseases constitute one of the major causes of morbidity and mortality in infants and young children globally. One of the main microorganisms causing diarrheal diseases is Campylobacter jejuni. For treatment of these diseases, Portulaca oleracea has been widely used as a folk remedy for a long time. This study was performed to investigate the antimicrobial activity of P. oleracea against gastroenteritis pathogens including C. jejuni. P. oleracea was extracted with petroleum ether, chloroform, ethylacetate, methanol, and hot water. The antimicrobial activity of the P. oleracea extracts was determined using the paper disc method, minimum inhibitory concentration, and the liquid culture method. The 10 $mg/m{\ell}$ ethylacetate extract showed the strongest antimicrobial activity against Salmonella typhimurium, Salmonella enteriditis, and Shigella spp.. The hot water extract from P. oleracea showed the highest anti-microbial activity against C. jejuni at 10~20 $mg/m{\ell}$. The hot water extract of P. oleracea retarded the growth of C. jejuni for 36 hr at $42^{\circ}C$.
Keywords
Portulaca oleracea; Campylobacter jejuni; antimicrobial activity;
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1 Sudjana AN, D'Orazio C, Ryan V, Rasool N, Ng J, Islam N, Riley TV, Hammer KA. 2009. Antimicrobial activity of commercial Olea europaea(olive) leaf extract. Int J Antimicro Agents 33:461-463   DOI   ScienceOn
2 Tan PV, Boda M, Etoa FX. 2010. In vitro and in vivo anti- Helicobacter/Campylobacter activity of the aqueous extract of Enantia chlorantha. Pharmaceutical Biol 48:349-356   DOI   ScienceOn
3 Wardwell LH, Huttenhower C, Garrett WS. 2011. Current concepts of the intestinal microbiota and the pathogenesis of infection. Curr Infect Dis Rep 13:28-34   DOI   ScienceOn
4 Xiang L, Xing D, Wang W, Wang R, Ding Y, Du L. 2005. Alkaloids from Portulaca oleracea L. Phytochem 66:2595-2601   DOI   ScienceOn
5 Ballal SA, Gallini CA, Segata N, Huttenhower C, Garrett WS 2011. Host and gut microbiota symbiotic factors: lessons from inflammatory bowel disease and successful symbionts. Cellular Microbiol 13:508-517   DOI   ScienceOn
6 Bhatnagar S, Singh KD, Sazawal S, Saxena S, Bhan MK. 1998. Efficacy of milk versus yoghurt offered as part of a mixed diet in acute noncholera diarrhea among malnourished children. J Pediatrics 132:999-1003   DOI   ScienceOn
7 Demol P. 1994. Human Campylobacteriosis: Clinical and epidermiological aspects. Dairy, Food Environ Sanit 14:314-316
8 Franco DA. 1988. Campylobacter species: Considerations for controlling a foodborne pathogen. J Food Prot 51:145-153   DOI
9 Friedman M. 2007. Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas. Mol Nutr Food Res 51:116-134   DOI   ScienceOn
10 Gonzalez-Sarrias A, Larrosa M, Tomas-Barberan F, Dolara P, Espin JC. 2010. NF-kappa B-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts. Br J Nutr 104:503-512   DOI   ScienceOn
11 Huang P, Farkas T, Marionneau S, Zhong W, Ruvoen-Clouet, N, Morrow AL, Altaye M, Pickering LK, Newburg DS, LePendu J, Jiang X. 2003. Noroviruses bind to human ABO and secretor histo-blood group antigens: Identification of 4 distinct strain-specific patterns. J Infectious Diseases 188: 19-31   DOI   ScienceOn
12 Hughey VL, Johnson EA 1987. Antimicrobial activity of lysozyme against bacteria involved in food spoilage and food-bone disease. Appl Environ Microbiol 53:2165-2170
13 Larrosa M, Gonzalez-Sarrias A, Yanez-Gascon MJ, Selma MV, Azorin-Orturil M, Toti S, Tomas-Barberan F, Dolara P, Espin JC. 2010. Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism. J Nutr Biochem 21:717-725   DOI   ScienceOn
14 Newburg DS, Ruiz-Palacios GM, Altaye M, Chaturvedi P, Meinzen-Derr J, Morrow AL. 2004. Innate protection conferred by fucosylated oligosaccharides of human milk against diarrhea in breastfed infants. Glycobiol 14:253-263   DOI
15 Newburg DS. 1992. Human milk mucin inhibits rotavirus replication and prevents experimental gastroenteritis. J Clin Invest 90:1984-1991   DOI
16 Newburg DS. 2000. Oligosaccharides in human milk and bacterial colonization. J Pediatr Gastroenterol Nutr 30:S8-S17   DOI
17 Bae JH. 2004. Antimicrobial effect of Portulaca oleracea extracts on food-brone pathogens. J Food Sci Nutr 9:306-311   과학기술학회마을   DOI   ScienceOn
18 Park SH, Kim DK, Bae JH. 2011. The antioxidant effect of Portulaca oleracea extracts and its antimicrobial activity on Helicobacter pylori. Korean J Food Nutr 24:306-311   과학기술학회마을   DOI   ScienceOn
19 Ruiz-Palacios GM, Cervantes LE, Ramos P, Chavex-Munguia B, Newburg DS. 2003. Campylobacter jejuni binds intestinal H(O) antigen ($fuc{\alpha}1$,2 $gal{\beta}1$,4glcNAc), and fucosyloligosaccharides of human milk inhibit its binding and infection. J Biol Chem 278:14112-14120   DOI   ScienceOn
20 Shen Z, Warren CD, Newburg DS. 2003. High-performance capillary electrophoresis of sialylated oligosaccharides of human milk. Anal Biochem 279:37-45
21 Balck RE, Levine MM, Clements ML, Hughes TP, Blaser M. 1988. Experimental Campylobacter jejuni infection in humans. J Infectious Disease 157:472-479   DOI   ScienceOn